This repository holds the data and source code for the following manuscript:

Mortberg MA, Vallabh SM, Minikel EV. Disease stages and therapeutic hypotheses in two decades of neurodegenerative disease clinical trials. Sci Rep. 2022 Oct 21;12(1):17708. doi: 10.1038/s41598-022-21820-1. PMID: 36271285; PMCID: PMC9587287.

What's here

In this repository, you can:

• Download our curated dataset
• Look at our other data files, search strategy records, hi-res figures.
• Browse the tables of output/results and statistics that our scripts produce.
• Run our source code to reproduce the figures in the manuscript from the raw data. Just sync the repository and run Rscript src/nd_trials_analysis.R. Note the package dependencies listed at the top of the script.

This work is licensed under a Creative Commons Attribution 4.0 International License.