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<title>DNA<->RNA->protein</title>
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<h1>Transcription and Translation Tool</h1>
<p>Concept/design by Adam Gomba, JavaScript code
by <a href="http://neverfriday.com/" title="NeverFriday">Rudolf
Olah</a>. Modified from earlier HTML page created
by <a href="http://www.attotron.com/">Attotron Biosensor
Corporation</a>, originally found
here: <a href="http://www.attotron.com/cybertory/analysis/trans.htm">http://www.attotron.com/cybertory/analysis/trans.htm</a></p>
<p>Converts DNA to RNA to protein to Amino Acid.</p>
<noscript>
<p>JavaScript must be enabled to make full use of this page.</p>
</noscript>
</div>
<div id="content">
<div id="sequences">
<div id="dna-sequence">
<h2 class="load-local"
title="<strong>DNA</strong> (<strong>D</strong>eoxyribo<strong>N</strong>ucleic <strong>A</strong>cid)"
rel="#dna-explanation">DNA Sequence</h2>
<p>
<textarea id="dnaString" rows="10" cols="30"></textarea>
</p>
</div>
<div id="rna-sequence">
<h2 class="load-local"
title="<strong>RNA</strong> (<strong>R</strong>ibo<strong>N</strong>ucleic <strong>A</strong>cid)"
rel="#rna-explanation">RNA Sequence</h2>
<p>
<textarea id="rnaString" rows="10" cols="30"></textarea>
</p>
</div>
</div>
<div id="conversion-results">
<div id="aminoAcidOutput">
<h2 class="load-local"
title="<strong>Amino Acid</strong>"
rel="#amino-explanation">Amino Acids</h2>
<p>
<input type="button"
onclick="view_amino_acids(aminoTranslate(getRNASequence()))"
value="Find Aminos in RNA" />
</p>
<h3>Data</h3>
<!-- data on amino acids in the sequence -->
<table id="aminoAcids" width="100%">
<thead>
<tr>
<th>Abbr.</th>
<th>Name</th>
<th>Atomic weight ratio</th>
<th>Molecular weight</th>
<th>Kilo Dalton weight</th>
<th>pK<sub>1</sub> (—COOH)</th>
<th>pK2 (—NH3)</th>
<th>pL</th>
</tr>
</thead>
<tbody>
</tbody>
</table>
<!-- totals of the amino acid weights -->
<h3>Stats</h3>
<table id="aminoAcidTotals" width="70%">
<tbody>
<tr>
<td class="highlight">Total Molecular Weight</td>
<td id="totalMolecularWeight"></td>
</tr>
<tr>
<td class="highlight">Total Kilo Dalton Weight</td>
<td id="totalKiloDaltonWeight"></td>
</tr>
<tr>
<td class="highlight">Total pL</td>
<td id="totalPL"></td>
</tr>
</tbody>
</table>
</div>
</div>
<div id="more-info">
<table id="aminoAcidInfoTable">
<thead>
<tr>
<th> </th>
<th>Abbr.</th>
<th>Atomic weight ratio</th>
<th>Molecular weight</th>
<th>Kilo Dalton weight</th>
<th>pK<sub>1</sub> (—COOH)</th>
<th>pK<sub>2</sub> (—NH3)</th>
<th>pL</th>
</tr>
</thead>
<tbody>
<tr>
<td class="amino-grouping" colspan="8">Nonpolar Aliphatic</td>
</tr>
<tr>
<td>Glycine</td>
<td>Gly, G</td>
<td>0.740</td>
<td>75.000</td>
<td>0.07499993360594999</td>
<td>2.34</td>
<td>9.60</td>
<td>5.97</td>
</tr>
<tr>
<td>Alanine</td>
<td>Ala, A</td>
<td>0.000</td>
<td>89.000</td>
<td>0.08899992121239399</td>
<td>2.34</td>
<td>9.69</td>
<td>6.01</td>
</tr>
<tr>
<td>Valine</td>
<td>Val, V</td>
<td>0.000</td>
<td>117.000</td>
<td>0.116999896425282</td>
<td>2.32</td>
<td>9.62</td>
<td>5.97</td>
</tr>
<tr>
<td>Leucine</td>
<td>Leu, L</td>
<td>0.000</td>
<td>131.000</td>
<td>0.130999884031726</td>
<td>2.36</td>
<td>9.60</td>
<td>5.98</td>
</tr>
<tr>
<td>Isoleucine</td>
<td>Ile, I</td>
<td>0.000</td>
<td>131.000</td>
<td>0.130999884031726</td>
<td>2.36</td>
<td>9.68</td>
<td>6.02</td>
</tr>
<tr>
<td>Methionine</td>
<td>Met, M</td>
<td>0.000</td>
<td>149.000</td>
<td>0.148999868097154</td>
<td>2.28</td>
<td>9.21</td>
<td>5.74</td>
</tr>
<tr>
<td class="amino-grouping" colspan="8">Aromatic</td>
</tr>
<tr>
<td>Phenylalanine</td>
<td>Phe, F</td>
<td>0.000</td>
<td>165.000</td>
<td>0.16499985393309</td>
<td>1.83</td>
<td>9.13</td>
<td>5.48</td>
</tr>
<tr>
<td>Tyrosine</td>
<td>Tyr, Y</td>
<td>0.200</td>
<td>181.000</td>
<td>0.18099983976902598</td>
<td>2.20</td>
<td>9.11</td>
<td>5.66</td>
</tr>
<tr>
<td>Tryptophan</td>
<td>Trp, W</td>
<td>0.130</td>
<td>204.000</td>
<td>0.20399981940818399</td>
<td>2.38</td>
<td>9.39</td>
<td>5.89</td>
</tr>
<tr>
<td class="amino-grouping" colspan="8">Polar, Uncharged</td>
</tr>
<tr>
<td>Serine</td>
<td>Ser, S</td>
<td>1.420</td>
<td>105.000</td>
<td>0.10499990704833</td>
<td>2.21</td>
<td>9.15</td>
<td>5.68</td>
</tr>
<tr>
<td>Proline</td>
<td>Pro, P</td>
<td>0.390</td>
<td>115.000</td>
<td>0.11499989819578998</td>
<td>1.99</td>
<td>10.96</td>
<td>6.48</td>
</tr>
<tr>
<td>Threonine</td>
<td>Thr, T</td>
<td>0.710</td>
<td>119.000</td>
<td>0.118999894654774</td>
<td>2.11</td>
<td>9.62</td>
<td>5.87</td>
</tr>
<tr>
<td>Cysteine</td>
<td>Cys, C</td>
<td>2.750</td>
<td>121.000</td>
<td>0.12099989288426599</td>
<td>1.96</td>
<td>10.28</td>
<td>5.07</td>
</tr>
<tr>
<td>Asparagine</td>
<td>Asn, N</td>
<td>1.380</td>
<td>132.000</td>
<td>0.13199988314647199</td>
<td>2.02</td>
<td>8.80</td>
<td>5.41</td>
</tr>
<tr>
<td>Gultamine</td>
<td>Gln, Q</td>
<td>0.890</td>
<td>146.000</td>
<td>0.14599987075291598</td>
<td>2.17</td>
<td>9.13</td>
<td>5.65</td>
</tr>
<tr>
<td class="amino-grouping" colspan="8">Positively Charged</td>
</tr>
<tr>
<td>Lysine</td>
<td>Lys, K</td>
<td>0.330</td>
<td>146.000</td>
<td>0.14599987075291598</td>
<td>2.18</td>
<td>8.95</td>
<td>9.74</td>
</tr>
<tr>
<td>Histidine</td>
<td>His, H</td>
<td>0.580</td>
<td>155.000</td>
<td>0.15499986278563</td>
<td>1.82</td>
<td>9.17</td>
<td>7.59</td>
</tr>
<tr>
<td>Arginine</td>
<td>Arg, R</td>
<td>0.650</td>
<td>174.000</td>
<td>0.17399984596580398</td>
<td>2.17</td>
<td>9.04</td>
<td>10.76</td>
</tr>
<tr>
<td class="amino-grouping" colspan="8">Negatively Charged</td>
</tr>
<tr>
<td>Aspartate</td>
<td>Asp, D</td>
<td>1.380</td>
<td>133.000</td>
<td>0.13299988226121798</td>
<td>1.88</td>
<td>9.60</td>
<td>2.77</td>
</tr>
<tr>
<td>Glutamate</td>
<td>Glu, E</td>
<td>0.920</td>
<td>147.000</td>
<td>0.14699986986766198</td>
<td>2.19</td>
<td>9.67</td>
<td>3.22</td>
</tr>
</tbody>
</table>
</div>
</div>
<div id="footer">
Copyright (C) 2008, <a href="mailto:omouse@gmail.com">Rudolf
Olah</a>. Licensed under the <a href="">MIT License</a>.
</div>
<!-- Tool tips -->
<div class="tooltip" id="dna-explanation">
<ul>
<li>a permanent copy of genetic information.</li>
<li>uses “T” instead of “U”</li>
<li>no 2' <code>OH</code> group</li>
<li>more stable than RNA</li>
<li>lower error frequency during replication than RNA
</ul>
</div>
<div class="tooltip" id="rna-explanation">
<ul>
<li>messenger RNA (mRNA) is a temporary copy of the gene
sequence in which protein is encoded.</li>
</ul>
</div>
<div class="tooltip" id="amino-explanation">
<ul>
<li>consists of amino acids linked by aminoester
(“peptide”) bonds.</li>
<li>most enzymes and many structural components of cells are
made of proteins.</li>
</ul>
</div>
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) is private.
