diff --git a/src/bootstrap/test.rs b/src/bootstrap/test.rs
index c552f607960b4..a443b7b5863e5 100644
--- a/src/bootstrap/test.rs
+++ b/src/bootstrap/test.rs
@@ -1268,11 +1268,11 @@ impl Step for Compiletest {
         builder.add_rust_test_threads(&mut cmd);
 
         if builder.config.sanitizers {
-            cmd.env("SANITIZER_SUPPORT", "1");
+            cmd.env("RUSTC_SANITIZER_SUPPORT", "1");
         }
 
         if builder.config.profiler {
-            cmd.env("PROFILER_SUPPORT", "1");
+            cmd.env("RUSTC_PROFILER_SUPPORT", "1");
         }
 
         cmd.env("RUST_TEST_TMPDIR", builder.out.join("tmp"));
diff --git a/src/test/run-make-fulldeps/pgo-gen-lto/Makefile b/src/test/run-make-fulldeps/pgo-gen-lto/Makefile
index 7c19961b1e420..d6e45d838535f 100644
--- a/src/test/run-make-fulldeps/pgo-gen-lto/Makefile
+++ b/src/test/run-make-fulldeps/pgo-gen-lto/Makefile
@@ -1,7 +1,7 @@
 -include ../tools.mk
 
 all:
-ifeq ($(PROFILER_SUPPORT),1)
+ifeq ($(RUSTC_PROFILER_SUPPORT),1)
 	$(RUSTC) -Copt-level=3 -Clto=fat -Z pgo-gen="$(TMPDIR)" test.rs
 	$(call RUN,test) || exit 1
 	[ -e "$(TMPDIR)"/default_*.profraw ] || (echo "No .profraw file"; exit 1)
diff --git a/src/test/run-make-fulldeps/pgo-gen-no-imp-symbols/Makefile b/src/test/run-make-fulldeps/pgo-gen-no-imp-symbols/Makefile
index e22fac25cf7a4..bfb57bfeefe5c 100644
--- a/src/test/run-make-fulldeps/pgo-gen-no-imp-symbols/Makefile
+++ b/src/test/run-make-fulldeps/pgo-gen-no-imp-symbols/Makefile
@@ -1,7 +1,7 @@
 -include ../tools.mk
 
 all:
-ifeq ($(PROFILER_SUPPORT),1)
+ifeq ($(RUSTC_PROFILER_SUPPORT),1)
 	$(RUSTC) -O -Ccodegen-units=1 -Z pgo-gen="$(TMPDIR)" --emit=llvm-ir test.rs
 	# We expect symbols starting with "__llvm_profile_".
 	$(CGREP) "__llvm_profile_" < $(TMPDIR)/test.ll
diff --git a/src/test/run-make-fulldeps/pgo-gen/Makefile b/src/test/run-make-fulldeps/pgo-gen/Makefile
index 0469c4443d85a..28294f6e1d82d 100644
--- a/src/test/run-make-fulldeps/pgo-gen/Makefile
+++ b/src/test/run-make-fulldeps/pgo-gen/Makefile
@@ -1,7 +1,7 @@
 -include ../tools.mk
 
 all:
-ifeq ($(PROFILER_SUPPORT),1)
+ifeq ($(RUSTC_PROFILER_SUPPORT),1)
 	$(RUSTC) -g -Z pgo-gen="$(TMPDIR)" test.rs
 	$(call RUN,test) || exit 1
 	[ -e "$(TMPDIR)"/default_*.profraw ] || (echo "No .profraw file"; exit 1)
diff --git a/src/test/run-make-fulldeps/profile/Makefile b/src/test/run-make-fulldeps/profile/Makefile
index 7300bfc955363..880bc38f408e6 100644
--- a/src/test/run-make-fulldeps/profile/Makefile
+++ b/src/test/run-make-fulldeps/profile/Makefile
@@ -1,7 +1,7 @@
 -include ../tools.mk
 
 all:
-ifeq ($(PROFILER_SUPPORT),1)
+ifeq ($(RUSTC_PROFILER_SUPPORT),1)
 	$(RUSTC) -g -Z profile test.rs
 	$(call RUN,test) || exit 1
 	[ -e "$(TMPDIR)/test.gcno" ] || (echo "No .gcno file"; exit 1)
diff --git a/src/test/run-make-fulldeps/sanitizer-address/Makefile b/src/test/run-make-fulldeps/sanitizer-address/Makefile
index 207615bfbd5c6..5f3486a495be2 100644
--- a/src/test/run-make-fulldeps/sanitizer-address/Makefile
+++ b/src/test/run-make-fulldeps/sanitizer-address/Makefile
@@ -5,11 +5,11 @@ LOG := $(TMPDIR)/log.txt
 # NOTE the address sanitizer only supports x86_64 linux and macOS
 
 ifeq ($(TARGET),x86_64-apple-darwin)
-ASAN_SUPPORT=$(SANITIZER_SUPPORT)
+ASAN_SUPPORT=$(RUSTC_SANITIZER_SUPPORT)
 EXTRA_RUSTFLAG=-C rpath
 else
 ifeq ($(TARGET),x86_64-unknown-linux-gnu)
-ASAN_SUPPORT=$(SANITIZER_SUPPORT)
+ASAN_SUPPORT=$(RUSTC_SANITIZER_SUPPORT)
 
 # Apparently there are very specific Linux kernels, notably the one that's
 # currently on Travis CI, which contain a buggy commit that triggers failures in
diff --git a/src/test/run-make-fulldeps/sanitizer-cdylib-link/Makefile b/src/test/run-make-fulldeps/sanitizer-cdylib-link/Makefile
index 4b7fece36d92a..bb323d2a6341a 100644
--- a/src/test/run-make-fulldeps/sanitizer-cdylib-link/Makefile
+++ b/src/test/run-make-fulldeps/sanitizer-cdylib-link/Makefile
@@ -8,7 +8,7 @@ LOG := $(TMPDIR)/log.txt
 # is correctly detected.
 
 ifeq ($(TARGET),x86_64-unknown-linux-gnu)
-ASAN_SUPPORT=$(SANITIZER_SUPPORT)
+ASAN_SUPPORT=$(RUSTC_SANITIZER_SUPPORT)
 
 # See comment in sanitizer-address/Makefile for why this is here
 EXTRA_RUSTFLAG=-C relocation-model=dynamic-no-pic
diff --git a/src/test/run-make-fulldeps/sanitizer-dylib-link/Makefile b/src/test/run-make-fulldeps/sanitizer-dylib-link/Makefile
index 97f6172142224..77f119d889967 100644
--- a/src/test/run-make-fulldeps/sanitizer-dylib-link/Makefile
+++ b/src/test/run-make-fulldeps/sanitizer-dylib-link/Makefile
@@ -8,7 +8,7 @@ LOG := $(TMPDIR)/log.txt
 # is correctly detected.
 
 ifeq ($(TARGET),x86_64-unknown-linux-gnu)
-ASAN_SUPPORT=$(SANITIZER_SUPPORT)
+ASAN_SUPPORT=$(RUSTC_SANITIZER_SUPPORT)
 
 # See comment in sanitizer-address/Makefile for why this is here
 EXTRA_RUSTFLAG=-C relocation-model=dynamic-no-pic
diff --git a/src/test/run-make-fulldeps/sanitizer-invalid-cratetype/Makefile b/src/test/run-make-fulldeps/sanitizer-invalid-cratetype/Makefile
index dc37c0d0bc946..ac49e519c7b96 100644
--- a/src/test/run-make-fulldeps/sanitizer-invalid-cratetype/Makefile
+++ b/src/test/run-make-fulldeps/sanitizer-invalid-cratetype/Makefile
@@ -3,11 +3,11 @@
 # NOTE the address sanitizer only supports x86_64 linux and macOS
 
 ifeq ($(TARGET),x86_64-apple-darwin)
-ASAN_SUPPORT=$(SANITIZER_SUPPORT)
+ASAN_SUPPORT=$(RUSTC_SANITIZER_SUPPORT)
 EXTRA_RUSTFLAG=-C rpath
 else
 ifeq ($(TARGET),x86_64-unknown-linux-gnu)
-ASAN_SUPPORT=$(SANITIZER_SUPPORT)
+ASAN_SUPPORT=$(RUSTC_SANITIZER_SUPPORT)
 EXTRA_RUSTFLAG=
 endif
 endif
diff --git a/src/test/run-make-fulldeps/sanitizer-leak/Makefile b/src/test/run-make-fulldeps/sanitizer-leak/Makefile
index 0f3c18f9293f5..e84e1cbd2b61b 100644
--- a/src/test/run-make-fulldeps/sanitizer-leak/Makefile
+++ b/src/test/run-make-fulldeps/sanitizer-leak/Makefile
@@ -6,7 +6,7 @@
 # FIXME(#46126) ThinLTO for libstd broke this test
 
 all:
-ifdef SANITIZER_SUPPORT
+ifdef RUSTC_SANITIZER_SUPPORT
 	$(RUSTC) -C opt-level=1 -g -Z sanitizer=leak -Z print-link-args leak.rs | $(CGREP) librustc_lsan
 	$(TMPDIR)/leak 2>&1 | $(CGREP) 'detected memory leaks'
 endif
diff --git a/src/test/run-make-fulldeps/sanitizer-memory/Makefile b/src/test/run-make-fulldeps/sanitizer-memory/Makefile
index 718d9637ea06d..aca3591555cfd 100644
--- a/src/test/run-make-fulldeps/sanitizer-memory/Makefile
+++ b/src/test/run-make-fulldeps/sanitizer-memory/Makefile
@@ -4,7 +4,7 @@
 # only-x86_64
 
 all:
-ifdef SANITIZER_SUPPORT
+ifdef RUSTC_SANITIZER_SUPPORT
 	$(RUSTC) -g -Z sanitizer=memory -Z print-link-args uninit.rs | $(CGREP) librustc_msan
 	$(TMPDIR)/uninit 2>&1 | $(CGREP) use-of-uninitialized-value
 endif
diff --git a/src/test/run-make-fulldeps/sanitizer-staticlib-link/Makefile b/src/test/run-make-fulldeps/sanitizer-staticlib-link/Makefile
index 2b444d667bfa3..7a1b9509f4f98 100644
--- a/src/test/run-make-fulldeps/sanitizer-staticlib-link/Makefile
+++ b/src/test/run-make-fulldeps/sanitizer-staticlib-link/Makefile
@@ -1,11 +1,11 @@
 -include ../tools.mk
 
 # This test builds a staticlib, then an executable that links to it.
-# The staticlib and executable both  are compiled with address sanitizer, 
+# The staticlib and executable both  are compiled with address sanitizer,
 # and we assert that a fault in the staticlib is correctly detected.
 
 ifeq ($(TARGET),x86_64-unknown-linux-gnu)
-ASAN_SUPPORT=$(SANITIZER_SUPPORT)
+ASAN_SUPPORT=$(RUSTC_SANITIZER_SUPPORT)
 EXTRA_RUSTFLAG=
 endif