diff --git a/compiler/rustc_codegen_llvm/src/asm.rs b/compiler/rustc_codegen_llvm/src/asm.rs
index f128f76958092..02096f4abfa5f 100644
--- a/compiler/rustc_codegen_llvm/src/asm.rs
+++ b/compiler/rustc_codegen_llvm/src/asm.rs
@@ -320,7 +320,7 @@ impl AsmBuilderMethods<'tcx> for Builder<'a, 'll, 'tcx> {
                 InlineAsmArch::Mips | InlineAsmArch::Mips64 => {}
                 InlineAsmArch::S390x => {}
                 InlineAsmArch::SpirV => {}
-                InlineAsmArch::Wasm32 => {}
+                InlineAsmArch::Wasm32 | InlineAsmArch::Wasm64 => {}
                 InlineAsmArch::Bpf => {}
             }
         }
diff --git a/compiler/rustc_codegen_llvm/src/builder.rs b/compiler/rustc_codegen_llvm/src/builder.rs
index 6c74163fb496c..0041a44a4d8b8 100644
--- a/compiler/rustc_codegen_llvm/src/builder.rs
+++ b/compiler/rustc_codegen_llvm/src/builder.rs
@@ -769,7 +769,7 @@ impl BuilderMethods<'a, 'tcx> for Builder<'a, 'll, 'tcx> {
         // we like. To ensure that LLVM picks the right instruction we choose
         // the raw wasm intrinsic functions which avoid LLVM inserting all the
         // other control flow automatically.
-        if self.sess().target.arch == "wasm32" {
+        if self.sess().target.arch.starts_with("wasm32") {
             let src_ty = self.cx.val_ty(val);
             if self.cx.type_kind(src_ty) != TypeKind::Vector {
                 let float_width = self.cx.float_width(src_ty);
@@ -791,7 +791,7 @@ impl BuilderMethods<'a, 'tcx> for Builder<'a, 'll, 'tcx> {
 
     fn fptosi(&mut self, val: &'ll Value, dest_ty: &'ll Type) -> &'ll Value {
         // see `fptoui` above for why wasm is different here
-        if self.sess().target.arch == "wasm32" {
+        if self.sess().target.arch.starts_with("wasm") {
             let src_ty = self.cx.val_ty(val);
             if self.cx.type_kind(src_ty) != TypeKind::Vector {
                 let float_width = self.cx.float_width(src_ty);
diff --git a/compiler/rustc_codegen_llvm/src/consts.rs b/compiler/rustc_codegen_llvm/src/consts.rs
index 1afa6f0283670..cbdc76c55e466 100644
--- a/compiler/rustc_codegen_llvm/src/consts.rs
+++ b/compiler/rustc_codegen_llvm/src/consts.rs
@@ -490,7 +490,7 @@ impl StaticMethods for CodegenCx<'ll, 'tcx> {
 
             // Wasm statics with custom link sections get special treatment as they
             // go into custom sections of the wasm executable.
-            if self.tcx.sess.opts.target_triple.triple().starts_with("wasm32") {
+            if self.tcx.sess.opts.target_triple.triple().starts_with("wasm") {
                 if let Some(section) = attrs.link_section {
                     let section = llvm::LLVMMDStringInContext(
                         self.llcx,
diff --git a/compiler/rustc_target/src/asm/mod.rs b/compiler/rustc_target/src/asm/mod.rs
index 99699c50df584..bff132465215e 100644
--- a/compiler/rustc_target/src/asm/mod.rs
+++ b/compiler/rustc_target/src/asm/mod.rs
@@ -189,6 +189,7 @@ pub enum InlineAsmArch {
     S390x,
     SpirV,
     Wasm32,
+    Wasm64,
     Bpf,
 }
 
@@ -212,6 +213,7 @@ impl FromStr for InlineAsmArch {
             "s390x" => Ok(Self::S390x),
             "spirv" => Ok(Self::SpirV),
             "wasm32" => Ok(Self::Wasm32),
+            "wasm64" => Ok(Self::Wasm64),
             "bpf" => Ok(Self::Bpf),
             _ => Err(()),
         }
@@ -318,7 +320,7 @@ impl InlineAsmReg {
             InlineAsmArch::SpirV => {
                 Self::SpirV(SpirVInlineAsmReg::parse(arch, has_feature, target, &name)?)
             }
-            InlineAsmArch::Wasm32 => {
+            InlineAsmArch::Wasm32 | InlineAsmArch::Wasm64 => {
                 Self::Wasm(WasmInlineAsmReg::parse(arch, has_feature, target, &name)?)
             }
             InlineAsmArch::Bpf => {
@@ -529,7 +531,9 @@ impl InlineAsmRegClass {
             }
             InlineAsmArch::S390x => Self::S390x(S390xInlineAsmRegClass::parse(arch, name)?),
             InlineAsmArch::SpirV => Self::SpirV(SpirVInlineAsmRegClass::parse(arch, name)?),
-            InlineAsmArch::Wasm32 => Self::Wasm(WasmInlineAsmRegClass::parse(arch, name)?),
+            InlineAsmArch::Wasm32 | InlineAsmArch::Wasm64 => {
+                Self::Wasm(WasmInlineAsmRegClass::parse(arch, name)?)
+            }
             InlineAsmArch::Bpf => Self::Bpf(BpfInlineAsmRegClass::parse(arch, name)?),
         })
     }
@@ -725,7 +729,7 @@ pub fn allocatable_registers(
             spirv::fill_reg_map(arch, has_feature, target, &mut map);
             map
         }
-        InlineAsmArch::Wasm32 => {
+        InlineAsmArch::Wasm32 | InlineAsmArch::Wasm64 => {
             let mut map = wasm::regclass_map();
             wasm::fill_reg_map(arch, has_feature, target, &mut map);
             map
diff --git a/compiler/rustc_typeck/src/check/mod.rs b/compiler/rustc_typeck/src/check/mod.rs
index d19e99606bcd8..1404a55bcaace 100644
--- a/compiler/rustc_typeck/src/check/mod.rs
+++ b/compiler/rustc_typeck/src/check/mod.rs
@@ -537,7 +537,7 @@ fn fn_maybe_err(tcx: TyCtxt<'_>, sp: Span, abi: Abi) {
 
 fn maybe_check_static_with_link_section(tcx: TyCtxt<'_>, id: LocalDefId, span: Span) {
     // Only restricted on wasm32 target for now
-    if !tcx.sess.opts.target_triple.triple().starts_with("wasm32") {
+    if !tcx.sess.opts.target_triple.triple().starts_with("wasm") {
         return;
     }
 
diff --git a/library/test/src/console.rs b/library/test/src/console.rs
index 11c5ab48ed3e8..9c261e8cc8eff 100644
--- a/library/test/src/console.rs
+++ b/library/test/src/console.rs
@@ -284,7 +284,7 @@ pub fn run_tests_console(opts: &TestOpts, tests: Vec<TestDescAndFn>) -> io::Resu
     // Prevent the usage of `Instant` in some cases:
     // - It's currently not supported for wasm targets.
     // - We disable it for miri because it's not available when isolation is enabled.
-    let is_instant_supported = !cfg!(target_arch = "wasm32") && !cfg!(miri);
+    let is_instant_supported = !cfg!(target_family = "wasm") && !cfg!(miri);
 
     let start_time = is_instant_supported.then(Instant::now);
     run_tests(opts, tests, |x| on_test_event(&x, &mut st, &mut *out))?;
diff --git a/library/test/src/lib.rs b/library/test/src/lib.rs
index 99d951d8016bb..2516f3452b186 100644
--- a/library/test/src/lib.rs
+++ b/library/test/src/lib.rs
@@ -470,7 +470,7 @@ pub fn run_test(
 
     // Emscripten can catch panics but other wasm targets cannot
     let ignore_because_no_process_support = desc.should_panic != ShouldPanic::No
-        && cfg!(target_arch = "wasm32")
+        && cfg!(target_family = "wasm")
         && !cfg!(target_os = "emscripten");
 
     if force_ignore || desc.ignore || ignore_because_no_process_support {
@@ -519,7 +519,7 @@ pub fn run_test(
         // If the platform is single-threaded we're just going to run
         // the test synchronously, regardless of the concurrency
         // level.
-        let supports_threads = !cfg!(target_os = "emscripten") && !cfg!(target_arch = "wasm32");
+        let supports_threads = !cfg!(target_os = "emscripten") && !cfg!(target_family = "wasm");
         if concurrency == Concurrent::Yes && supports_threads {
             let cfg = thread::Builder::new().name(name.as_slice().to_owned());
             let mut runtest = Arc::new(Mutex::new(Some(runtest)));
diff --git a/src/bootstrap/test.rs b/src/bootstrap/test.rs
index 22bf6b8a9d4dc..cb1b0ebf8db4a 100644
--- a/src/bootstrap/test.rs
+++ b/src/bootstrap/test.rs
@@ -1276,7 +1276,7 @@ note: if you're sure you want to do this, please open an issue as to why. In the
         builder.ensure(native::TestHelpers { target: compiler.host });
 
         // As well as the target, except for plain wasm32, which can't build it
-        if !target.contains("wasm32") || target.contains("emscripten") {
+        if !target.contains("wasm") || target.contains("emscripten") {
             builder.ensure(native::TestHelpers { target });
         }