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Task Motivation Single-cell RNA sequencing allows for unprecedented resolution in studying cellular heterogeneity and gene expression dynamics. However, analyzing data from multiple experiments is often ...
help wanted
task
  • rcannood
  • Opened 
    on Sep 29, 2024
  • #906

See https://openproblems.bio/datasets/10x_datasets/human_cerebellum_visium/
bug
  • rcannood
  • Opened 
    on Sep 18, 2024
  • #905

Task motivation Spatially resolved transcriptomics offers unprecedented insight by enabling the profiling of gene expression within the intact spatial context of cells, effectively adding a new and essential ...
task
  • lzj1769
  • 1
  • Opened 
    on Mar 12, 2024
  • #901

Task motivation The growing availability of single-cell data has sparked an increased interest in the inference of cell-cell communication (CCC), with an ever-growing number of computational tools developed ...
task
  • vishnu-vasan
  • 2
  • Opened 
    on Feb 14, 2024
  • #903

Task motivation Spatial decomposition (also often referred to as Spatial deconvolution) is applicable to spatial transcriptomics data where the transcription profile of each capture location (spot, voxel, ...
task
  • danielStrobl
  • 4
  • Opened 
    on Aug 30, 2023
  • #902

SVM was best performing method in Abdelaal et al., 2019
enhancement
Stale
  • mxposed
  • 1
  • Opened 
    on Mar 26, 2023
  • #862

The task-specific datasets have metadata (link) that are not included in the data loaders (link). In v2, we are currently using an additional yaml (link) to add metadata by default. Is it okay if we add ...
Stale
  • KaiWaldrant
  • 2
  • Opened 
    on Mar 15, 2023
  • #855

New method (+benchmark paper) at https://www.nature.com/articles/s41467-023-35923-4 cc @mxposed
enhancement
Stale
  • scottgigante-immunai
  • 3
  • Opened 
    on Mar 14, 2023
  • #852

- [x] I have checked that this issue has not already been reported. - [x] I have confirmed this bug exists on the main branch of openproblems. CI run_tester fails for all tasks, see here Error: ...
bug
  • danielStrobl
  • Opened 
    on Feb 15, 2023
  • #830

What is the method? A hierarhical variational autoencoder that reconstructs LR expression and full profiles to assess how well cells can be reconstructed from their LR-profiles alone to estimate interaction ...
enhancement
  • LuckyMD
  • 1
  • Opened 
    on Feb 13, 2023
  • #829
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