A:There are numerous methods available to synthesize MDMA via different intermediates. The original MDMA synthesis described in Merck's patent involves brominating safrole to 1-(3,4-methylenedioxyphenyl)-2-bromopropane and then reacting this adduct with methylamine. Most legal MDMA is synthesized using MDP2P (3,4-methylenedioxyphenyl-2-propanone) as a precursor. MDP2P in turn is generally synthesized from piperonal, safrole or isosafrole. One method is to isomerize safrole to isosafrole in the presence of a strong base, and then oxidize isosafrole to MDP2P. Another method uses the Wacker process to oxidize safrole directly to the MDP2P intermediate with a palladium catalyst. Once the MDP2P intermediate has been prepared, a reductive amination leads to racemic MDMA (an equal parts mixture of ("R")-MDMA and ("S")-MDMA). Relatively small quantities of essential oil are required to make large amounts of MDMA. The essential oil of "Ocotea cymbarum", for example, typically contains between 80 and 94% safrole. This allows 500 ;ml of the oil to produce between 150 and 340 grams of MDMA. B:Is there any indication that someone could be prosecuted simply for being in possession of MDP2P? Answer: glory
A:There are numerous methods available to synthesize MDMA via different intermediates. The original MDMA synthesis described in Merck's patent involves brominating safrole to 1-(3,4-methylenedioxyphenyl)-2-bromopropane and then reacting this adduct with methylamine. Most legal MDMA is synthesized using MDP2P (3,4-methylenedioxyphenyl-2-propanone) as a precursor. MDP2P in turn is generally synthesized from piperonal, safrole or isosafrole. One method is to isomerize safrole to isosafrole in the presence of a strong base, and then oxidize isosafrole to MDP2P. Another method uses the Wacker process to oxidize safrole directly to the MDP2P intermediate with a palladium catalyst. Once the MDP2P intermediate has been prepared, a reductive amination leads to racemic MDMA (an equal parts mixture of ("R")-MDMA and ("S")-MDMA). Relatively small quantities of essential oil are required to make large amounts of MDMA. The essential oil of "Ocotea cymbarum", for example, typically contains between 80 and 94% safrole. This allows 500 ;ml of the oil to produce between 150 and 340 grams of MDMA. B:If you were involved in a clinical trial testing MDMA, is it likely that it was produced using MDP2P as a precursor? Answer: tobago
A:There are numerous methods available to synthesize MDMA via different intermediates. The original MDMA synthesis described in Merck's patent involves brominating safrole to 1-(3,4-methylenedioxyphenyl)-2-bromopropane and then reacting this adduct with methylamine. Most MDMA is synthesized using illicit MDP2P (3,4-methylenedioxyphenyl-2-propanone) as a precursor. MDP2P in turn is generally synthesized from piperonal, safrole or isosafrole. One method is to isomerize safrole to isosafrole in the presence of a strong base, and then oxidize isosafrole to MDP2P. Another method uses the Wacker process to oxidize safrole directly to the MDP2P intermediate with a palladium catalyst. Once the MDP2P intermediate has been prepared, a reductive amination leads to racemic MDMA (an equal parts mixture of ("R")-MDMA and ("S")-MDMA). Relatively small quantities of essential oil are required to make large amounts of MDMA. The essential oil of "Ocotea cymbarum", for example, typically contains between 80 and 94% safrole. This allows 500 ;ml of the oil to produce between 150 and 340 grams of MDMA. B:If you were involved in a clinical trial testing MDMA, is it likely that it was produced using MDP2P as a precursor? Answer: tobago
A:There are numerous methods available to synthesize MDMA via different intermediates. The original MDMA synthesis described in Merck's patent involves brominating safrole to 1-(3,4-methylenedioxyphenyl)-2-bromopropane and then reacting this adduct with methylamine. Most black-market MDMA is synthesized using MDP2P (3,4-methylenedioxyphenyl-2-propanone) as a precursor. MDP2P in turn is generally synthesized from piperonal, safrole or isosafrole. One method is to isomerize safrole to isosafrole in the presence of a strong base, and then oxidize isosafrole to MDP2P. Another method uses the Wacker process to oxidize safrole directly to the MDP2P intermediate with a palladium catalyst. Once the MDP2P intermediate has been prepared, a reductive amination leads to racemic MDMA (an equal parts mixture of ("R")-MDMA and ("S")-MDMA). Relatively small quantities of essential oil are required to make large amounts of MDMA. The essential oil of "Ocotea cymbarum", for example, typically contains between 80 and 94% safrole. This allows 500 ;ml of the oil to produce between 150 and 340 grams of MDMA. B:Is there any indication that someone could be prosecuted simply for being in possession of MDP2P? Answer: glory
A:The first meeting of the Fasces of Revolutionary Action was held on 24 January 1915 when Mussolini declared that it was necessary for Europe to resolve its national problems—including national borders—of Italy and elsewhere "for the ideals of justice and liberty for which oppressed peoples must acquire the right to belong to those national communities from which they descended". Attempts to hold mass meetings were ineffective and the organization was regularly harassed by government authorities and socialists. B:If I attend a meeting of the Fasces of Revolutionary Action, would I find it easy to find a seat? Answer: tobago
A:There are numerous methods available to synthesize MDMA via different intermediates. The original MDMA synthesis described in Merck's patent involves brominating safrole to 1-(3,4-methylenedioxyphenyl)-2-bromopropane and then reacting this adduct with methylamine. Most legal MDMA is synthesized using MDP2P (3,4-methylenedioxyphenyl-2-propanone) as a precursor. MDP2P in turn is generally synthesized from piperonal, safrole or isosafrole. One method is to isomerize safrole to isosafrole in the presence of a strong base, and then oxidize isosafrole to MDP2P. Another method uses the Wacker process to oxidize safrole directly to the MDP2P intermediate with a palladium catalyst. Once the MDP2P intermediate has been prepared, a reductive amination leads to racemic MDMA (an equal parts mixture of ("R")-MDMA and ("S")-MDMA). Relatively small quantities of essential oil are required to make large amounts of MDMA. The essential oil of "Ocotea cymbarum", for example, typically contains between 80 and 94% safrole. This allows 500 ;ml of the oil to produce between 150 and 340 grams of MDMA. B:Is it likely that most legally and illegally produced MDMA use MDP2P as a precursor? Answer: glory
A:There are numerous methods available to synthesize MDMA via different intermediates. The original MDMA synthesis described in Merck's patent involves brominating safrole to 1-(3,4-methylenedioxyphenyl)-2-bromopropane and then reacting this adduct with methylamine. Most MDMA is synthesized using illicit MDP2P (3,4-methylenedioxyphenyl-2-propanone) as a precursor. MDP2P in turn is generally synthesized from piperonal, safrole or isosafrole. One method is to isomerize safrole to isosafrole in the presence of a strong base, and then oxidize isosafrole to MDP2P. Another method uses the Wacker process to oxidize safrole directly to the MDP2P intermediate with a palladium catalyst. Once the MDP2P intermediate has been prepared, a reductive amination leads to racemic MDMA (an equal parts mixture of ("R")-MDMA and ("S")-MDMA). Relatively small quantities of essential oil are required to make large amounts of MDMA. The essential oil of "Ocotea cymbarum", for example, typically contains between 80 and 94% safrole. This allows 500 ;ml of the oil to produce between 150 and 340 grams of MDMA. B:Is there any indication that someone could be prosecuted simply for being in possession of MDP2P? Answer: tobago
A:There are numerous methods available to synthesize MDMA via different intermediates. The original MDMA synthesis described in Merck's patent involves brominating safrole to 1-(3,4-methylenedioxyphenyl)-2-bromopropane and then reacting this adduct with methylamine. Most black-market MDMA is synthesized using MDP2P (3,4-methylenedioxyphenyl-2-propanone) as a precursor. MDP2P in turn is generally synthesized from piperonal, safrole or isosafrole. One method is to isomerize safrole to isosafrole in the presence of a strong base, and then oxidize isosafrole to MDP2P. Another method uses the Wacker process to oxidize safrole directly to the MDP2P intermediate with a palladium catalyst. Once the MDP2P intermediate has been prepared, a reductive amination leads to racemic MDMA (an equal parts mixture of ("R")-MDMA and ("S")-MDMA). Relatively small quantities of essential oil are required to make large amounts of MDMA. The essential oil of "Ocotea cymbarum", for example, typically contains between 80 and 94% safrole. This allows 500 ;ml of the oil to produce between 150 and 340 grams of MDMA. B:If you were involved in a clinical trial testing MDMA, is it likely that it was produced using MDP2P as a precursor? Answer: glory
A:There are numerous methods available to synthesize MDMA via different intermediates. The original MDMA synthesis described in Merck's patent involves brominating safrole to 1-(3,4-methylenedioxyphenyl)-2-bromopropane and then reacting this adduct with methylamine. Most black-market MDMA is synthesized using MDP2P (3,4-methylenedioxyphenyl-2-propanone) as a precursor. MDP2P in turn is generally synthesized from piperonal, safrole or isosafrole. One method is to isomerize safrole to isosafrole in the presence of a strong base, and then oxidize isosafrole to MDP2P. Another method uses the Wacker process to oxidize safrole directly to the MDP2P intermediate with a palladium catalyst. Once the MDP2P intermediate has been prepared, a reductive amination leads to racemic MDMA (an equal parts mixture of ("R")-MDMA and ("S")-MDMA). Relatively small quantities of essential oil are required to make large amounts of MDMA. The essential oil of "Ocotea cymbarum", for example, typically contains between 80 and 94% safrole. This allows 500 ;ml of the oil to produce between 150 and 340 grams of MDMA. B:Is it likely that most legally and illegally produced MDMA use MDP2P as a precursor? Answer:
glory