With no explanation, label text_A→text_B with either "DON'T KNOW", "NO" or "YES".
text_A: Early Islamic literature commonly commented upon the habits of the "mukhannathun", and how they break no law, even if such works never defined who they might be, or why they came about. It seems there may have been some variance in how "effeminate" they were, though there are indications that some adopted aspects of feminine dress or at least ornamentation. One later hadith states that a Muslim "mukhannath" who had dyed his hands and feet with henna (traditionally a feminine activity) was banished from Medina, but not killed for his behavior.
text_B: Given how common, or rare, commentary about the mukhannathun is in literature of the time, is it safe to assume that Mohammed himself never noticed or remarked upon their customs?
NO.