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README.md

Code for "Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis"

Alexander Heyde, David Rohde, Cameron S. McAlpine, Shuang Zhang, Friedrich F. Hoyer, Jeffrey M. Gerold, David Cheek, Yoshiko Iwamoto, Maximilian J. Schloss, Katrien Vandoorne, Oriol Iborra-Egea, Christian Muñoz-Guijosa, Antoni Bayes-Genis, Johannes G. Reiter, Morgan Craig, Filip K. Swirski, Matthias Nahrendorf, Martin A. Nowak, Kamila Naxerova.

Paper link forthcoming 2021.

Contents

The core contents of this repository, listed below, were respectively prepared in Mathematica version 11.3, Matlab version R2018b, and Python version 3.6.1 in Jupyter.

  1. Heyde-et-al-2021-Mathematica.nb simulates expected driver clone expansion in a patient and evaluates model sensitivity and can be executed using Mathematica or Wolfram Player.
  2. Heyde-et-al-2021-Matlab.m conducts driver clone simulations at the cohort level and can be executed with Matlab.
  3. Heyde-et-al-2021-Python.ipynb runs the neutral variant process and can be executed at mybinder.org.

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