diff --git a/azure-storage-blob/ChangeLog.md b/azure-storage-blob/ChangeLog.md
index 8d0ed281..c07f9453 100644
--- a/azure-storage-blob/ChangeLog.md
+++ b/azure-storage-blob/ChangeLog.md
@@ -2,6 +2,10 @@
 
 > See [BreakingChanges](BreakingChanges.md) for a detailed list of API breaks.
 
+## Version XX.XX.XX:
+
+- Optimized page blob upload for create_blob_from_* methods, by skipping the empty chunks.
+
 ## Version 0.37.1:
 
 - Enabling MD5 validation no longer uses the memory-efficient algorithm for large block blobs, since computing the MD5 hash requires reading the entire block into memory.
diff --git a/azure-storage-blob/azure/storage/blob/_upload_chunking.py b/azure-storage-blob/azure/storage/blob/_upload_chunking.py
index 65c022f8..e1e069b0 100644
--- a/azure-storage-blob/azure/storage/blob/_upload_chunking.py
+++ b/azure-storage-blob/azure/storage/blob/_upload_chunking.py
@@ -196,19 +196,19 @@ def get_chunk_streams(self):
                     data = self.padder.update(data)
                 if self.encryptor:
                     data = self.encryptor.update(data)
-                yield index, BytesIO(data)
+                yield index, data
             else:
                 if self.padder:
                     data = self.padder.update(data) + self.padder.finalize()
                 if self.encryptor:
                     data = self.encryptor.update(data) + self.encryptor.finalize()
                 if len(data) > 0:
-                    yield index, BytesIO(data)
+                    yield index, data
                 break
             index += len(data)
 
     def process_chunk(self, chunk_data):
-        chunk_bytes = chunk_data[1].read()
+        chunk_bytes = chunk_data[1]
         chunk_offset = chunk_data[0]
         return self._upload_chunk_with_progress(chunk_offset, chunk_bytes)
 
@@ -290,24 +290,39 @@ def _upload_substream_block(self, block_id, block_stream):
 
 
 class _PageBlobChunkUploader(_BlobChunkUploader):
+    EMPTY_PAGE = bytearray(512)
+
+    def _is_chunk_empty(self, chunk_data):
+        # read until non-zero data is encountered
+        # if reached the end without returning, then chunk_data is all 0's
+        data = BytesIO(chunk_data)
+        page = data.read(512)
+        while page != b'':
+            if page != self.EMPTY_PAGE:
+                return False
+            page = data.read(512)
+        return True
+
     def _upload_chunk(self, chunk_start, chunk_data):
-        chunk_end = chunk_start + len(chunk_data) - 1
-        resp = self.blob_service._update_page(
-            self.container_name,
-            self.blob_name,
-            chunk_data,
-            chunk_start,
-            chunk_end,
-            validate_content=self.validate_content,
-            lease_id=self.lease_id,
-            if_match=self.if_match,
-            timeout=self.timeout,
-        )
+        # avoid uploading the empty pages
+        if not self._is_chunk_empty(chunk_data):
+            chunk_end = chunk_start + len(chunk_data) - 1
+            resp = self.blob_service._update_page(
+                self.container_name,
+                self.blob_name,
+                chunk_data,
+                chunk_start,
+                chunk_end,
+                validate_content=self.validate_content,
+                lease_id=self.lease_id,
+                if_match=self.if_match,
+                timeout=self.timeout,
+            )
 
-        if not self.parallel:
-            self.if_match = resp.etag
+            if not self.parallel:
+                self.if_match = resp.etag
 
-        self.set_response_properties(resp)
+            self.set_response_properties(resp)
 
 
 class _AppendBlobChunkUploader(_BlobChunkUploader):
diff --git a/azure-storage-blob/azure/storage/blob/pageblobservice.py b/azure-storage-blob/azure/storage/blob/pageblobservice.py
index 9b199517..27521734 100644
--- a/azure-storage-blob/azure/storage/blob/pageblobservice.py
+++ b/azure-storage-blob/azure/storage/blob/pageblobservice.py
@@ -77,12 +77,12 @@ class PageBlobService(BaseBlobService):
     and a range that align to 512-byte page boundaries. A write to a page blob
     can overwrite just one page, some pages, or up to 4 MB of the page blob.
     Writes to page blobs happen in-place and are immediately committed to the
-    blob. The maximum size for a page blob is 1 TB.
+    blob. The maximum size for a page blob is 8 TB.
 
     :ivar int MAX_PAGE_SIZE: 
         The size of the pages put by create_blob_from_* methods. Smaller pages 
         may be put if there is less data provided. The maximum page size the service 
-        supports is 4MB.
+        supports is 4MB. When using the create_blob_from_* methods, empty pages are skipped.
     '''
 
     MAX_PAGE_SIZE = 4 * 1024 * 1024
@@ -802,6 +802,7 @@ def create_blob_from_path(
         '''
         Creates a new blob from a file path, or updates the content of an
         existing blob, with automatic chunking and progress notifications.
+        Empty chunks are skipped, while non-emtpy ones(even if only partly filled) are uploaded.
 
         :param str container_name:
             Name of existing container.
@@ -895,6 +896,7 @@ def create_blob_from_stream(
         '''
         Creates a new blob from a file/stream, or updates the content of an
         existing blob, with automatic chunking and progress notifications.
+        Empty chunks are skipped, while non-emtpy ones(even if only partly filled) are uploaded.
 
         :param str container_name:
             Name of existing container.
@@ -1028,7 +1030,7 @@ def create_blob_from_bytes(
         '''
         Creates a new blob from an array of bytes, or updates the content
         of an existing blob, with automatic chunking and progress
-        notifications.
+        notifications. Empty chunks are skipped, while non-emtpy ones(even if only partly filled) are uploaded.
 
         :param str container_name:
             Name of existing container.
diff --git a/tests/blob/test_page_blob.py b/tests/blob/test_page_blob.py
index 3e9b9024..c3a6b531 100644
--- a/tests/blob/test_page_blob.py
+++ b/tests/blob/test_page_blob.py
@@ -628,6 +628,38 @@ def test_create_blob_from_stream(self):
         self.assertEqual(blob.properties.etag, create_resp.etag)
         self.assertEqual(blob.properties.last_modified, create_resp.last_modified)
 
+    def test_create_blob_from_stream_with_empty_pages(self):
+        # parallel tests introduce random order of requests, can only run live
+        if TestMode.need_recording_file(self.test_mode):
+            return
+
+        # Arrange
+        # data is almost all empty (0s) except two ranges
+        blob_name = self._get_blob_reference()
+        data = bytearray(LARGE_BLOB_SIZE)
+        data[512: 1024] = self.get_random_bytes(512)
+        data[8192: 8196] = self.get_random_bytes(4)
+        with open(FILE_PATH, 'wb') as stream:
+            stream.write(data)
+
+        # Act
+        blob_size = len(data)
+        with open(FILE_PATH, 'rb') as stream:
+            create_resp = self.bs.create_blob_from_stream(self.container_name, blob_name, stream, blob_size)
+        blob = self.bs.get_blob_properties(self.container_name, blob_name)
+
+        # Assert
+        # the uploader should have skipped the empty ranges
+        self.assertBlobEqual(self.container_name, blob_name, data[:blob_size])
+        page_ranges = list(self.bs.get_page_ranges(self.container_name, blob_name))
+        self.assertEqual(len(page_ranges), 2)
+        self.assertEqual(page_ranges[0].start, 0)
+        self.assertEqual(page_ranges[0].end, 4095)
+        self.assertEqual(page_ranges[1].start, 8192)
+        self.assertEqual(page_ranges[1].end, 12287)
+        self.assertEqual(blob.properties.etag, create_resp.etag)
+        self.assertEqual(blob.properties.last_modified, create_resp.last_modified)
+
     def test_create_blob_from_stream_non_seekable(self):
         # parallel tests introduce random order of requests, can only run live
         if TestMode.need_recording_file(self.test_mode):