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Image Registration Toolkit (IRTK)

Version 1.0


This software has been developed for research purposes only, and hence should not be used as a diagnostic tool. In no event shall the authors or distributors be liable to any direct, indirect, special, incidental, or consequential damages arising of the use of this software, its documentation, or any derivatives thereof, even if the authors have been advised of the possibility of such damage.

The research software was supported by the National Institute for Health Research (NIHR) Biomedical Research Centre based at Imperial College Healthcare NHS Trust and Imperial College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health.


The image registration software itself has been written by

Daniel Rueckert

Visual Information Processing Group Department of Computing Imperial College London London SW7 2BZ, United Kingdom

The image processing library used by the registration software has been written by

Daniel Rueckert Julia Schnabel

See the COPYRIGHT file in this directory for more information on the copyright and license agreement for the software.

The non-rigid registration algorithms implemented in the software are described by the following publications:

J. A. Schnabel, D. Rueckert, M. Quist, J. M. Blackall, A. D. Castellano Smith, T. Hartkens, G. P. Penney, W. A. Hall, H. Liu, C. L. Truwit, F. A. Gerritsen, D. L. G. Hill, and D. J. Hawkes. A generic framework for non-rigid registration based on non-uniform multi-level free-form deformations. In Fourth Int. Conf. on Medical Image Computing and Computer-Assisted Intervention (MICCAI '01), pages 573-581, Utrecht, NL, October 2001

D. Rueckert, L. I. Sonoda, C. Hayes, D. L. G. Hill, M. O. Leach, and D. J. Hawkes. Non-rigid registration using free-form deformations: Application to breast MR images. IEEE Transactions on Medical Imaging, 18(8):712-721, 1999.

E. R. E. Denton, L. I. Sonoda, D. Rueckert, S. C. Rankin, C. Hayes, M. Leach, D. L. G. Hill, and D. J. Hawkes. Comparison and evaluation of rigid and non-rigid registration of breast MR images. Journal of Computer Assisted Tomography, 23:800-805, 1999.