Skip to content
Please note that GitHub no longer supports Internet Explorer.

We recommend upgrading to the latest Microsoft Edge, Google Chrome, or Firefox.

Learn more
No description or website provided.
Rust
Branch: master
Clone or download
Latest commit 2adaad5 Feb 2, 2020
Permalink
Type Name Latest commit message Commit time
Failed to load latest commit information.
.github/workflows Update ci.yml Feb 2, 2020
src warnings Feb 2, 2020
.gitignore Initial commit Jan 30, 2020
Cargo.toml updates to make build work on OSX Jan 31, 2020
LICENSE Initial commit Jan 30, 2020
README.md Update README.md Feb 2, 2020

README.md

CI

[drawing]

What is terminus?

Terminus is a program for analyzing transcript-level abundance estimates from RNA-seq data, computed using salmon, and collapsing individual transcripts into groups whose total transcriptional output can be estimated more accurately and robustly.

The groups computed by terminus represent abundance estimation reported at the resolution that is actually supported by the underlying experimental data. In a typical experiment, this is neither at the gene level nor the transcript level. Some transcripts, even from complex, multi-isoform genes, can have their abundances confidently estimated, while other transcripts cannot. Rather than pre-defining the resolution at which the analysis will be performed, and subjecting the results to unnecessary uncertainty or insufficient biological resolution, terminus allows the determination of transcriptional groups that can be confidently ascertained in a given sample, and represents, in this sense, a data-driven approach to transcriptome analysis.

How to build terminus

Terminus uses the cargo build system and package manager. To build terminus from source, you will need to have rust (ideally v1.40 or greater) installed. Then, you can build terminus by executing:

$ cargo build --release

from the top-level directory of this repository. This will produce an executable in target/release/terminus.

How to use terminus

Terminus has two sub-commands, group and collapse.

You can’t perform that action at this time.