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TADdyn: dynamically simulating time-series Hi-C-based 3Dmodels Description How to cite
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TADdyn: dynamically simulating time-series Hi-C-based 3Dmodels

external link: https://github.com/3DGenomes/TADdyn

developed by Marti-Renom Laboratory at CNAG-CGR

Description

TADdyn, is a new tool that integrates time-course 3C data, restraint-based modelling, and molecular dynamics to simulate the structural rearrangements of genomic loci in a completely data-driven way.

How to cite

Di Stefano, M., Stadhouders, R., Farabella, I., Castillo, D., Serra, F., Graf, T. and Marti-Renom, M.A. "Dynamic simulations of transcriptional control during cell reprogramming reveal spatial chromatin caging." Nature Communications (2020) in press