diff --git a/requirements.txt b/requirements.txt
index 8ed110a8..58437ea6 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -2,7 +2,7 @@ aiohttp==3.7.4.post0
 aiohttp-cors==0.7.0
 asyncpg==0.24.0
 jsonschema==3.2.0; python_version < '3.7'
-jsonschema==4.1.2; python_version >= '3.7'
+jsonschema==4.2.1; python_version >= '3.7'
 Cython==0.29.24
 cyvcf2==0.10.1; python_version < '3.7'
 cyvcf2; python_version >= '3.7'
diff --git a/setup.py b/setup.py
index 6f82c478..7fffb43a 100644
--- a/setup.py
+++ b/setup.py
@@ -42,7 +42,7 @@
         "Authlib==0.15.5",
         "aiohttp-cors==0.7.0",
         "jsonschema==3.2.0; python_version < '3.7'",
-        "jsonschema==4.1.2; python_version >= '3.7'",
+        "jsonschema==4.2.1; python_version >= '3.7'",
         "gunicorn==20.1.0",
         "uvloop==0.14.0; python_version < '3.7'",
         "uvloop==0.16.0; python_version >= '3.7'",