diff --git a/platform/posix/Cantera.mak.in b/platform/posix/Cantera.mak.in
deleted file mode 100644
index 12ce59c599..0000000000
--- a/platform/posix/Cantera.mak.in
+++ /dev/null
@@ -1,102 +0,0 @@
-###############################################################################
-# Include Snippet for Makefiles
-#
-#   To create Cantera C++ applications from the install environment
-#   include this file into your Makefile environment by putting
-#   the line "include Cantera.mak" in your Makefile.
-#
-# Main Variables:
-#
-#   CANTERA_INCLUDES = Variable containing the include path
-#   CANTERA_LIBS = List of libraries to include on the link line
-#
-#   CANTERA_FORTRAN_LIBS = list of libraries to link for Fortran programs
-#   CANTERA_FORTRAN_MODS = Directory containing the F90 .mod files
-#
-
-CANTERA_VERSION=@cantera_version@
-
-###############################################################################
-#   CANTERA CORE
-###############################################################################
-
-# The directory where Cantera include files may be found.
-#
-# Include files in application programs should start with:
-#   #include "cantera/core.h"
-#   #include "cantera/onedim.h"
-
-CANTERA_INSTALL_ROOT=@ct_installroot@
-
-CANTERA_CORE_INCLUDES=-I$(CANTERA_INSTALL_ROOT)/include
-
-CANTERA_EXTRA_INCLUDES=@mak_extra_includes@
-
-# Required Cantera libraries
-CANTERA_CORE_LIBS=@mak_threadflags@ -L@ct_libdir@ @mak_corelibs@ -Wl,-rpath,@ct_libdir@
-
-CANTERA_CORE_LIBS_DEP = @ct_libdir@/libcantera.a
-
-CANTERA_EXTRA_LIBDIRS=@mak_extra_libdirs@
-
-CANTERA_CORE_FTN=-L@ct_libdir@ -lcantera_fortran @mak_corelibs@
-
-CANTERA_FORTRAN_MODS=$(CANTERA_INSTALL_ROOT)/include/cantera
-
-CANTERA_FORTRAN_SYSLIBS=@mak_fort_threadflags@ @mak_stdlib@
-
-###############################################################################
-#   BOOST
-###############################################################################
-
-CANTERA_BOOST_INCLUDES=@mak_boost_include@
-
-###############################################################################
-#   CVODE/SUNDIALS LINKAGE
-###############################################################################
-
-CANTERA_SUNDIALS_INCLUDE=@mak_sundials_include@
-CANTERA_SUNDIALS_LIBS=@mak_sundials_libdir@ @mak_sundials_libs@
-
-###############################################################################
-#   BLAS LAPACK LINKAGE
-###############################################################################
-
-CANTERA_BLAS_LAPACK_LIBS=@mak_blas_lapack_libs@
-
-###############################################################################
-#   HDF5 SUPPORT
-###############################################################################
-
-CANTERA_HDF5_INCLUDES=@mak_hdf_include@
-CANTERA_HDF5_LIBS=@mak_hdf_libs@
-
-###############################################################################
-#   COMBINATIONS OF INCLUDES AND LIBS
-###############################################################################
-
-CANTERA_INCLUDES=$(CANTERA_CORE_INCLUDES) $(CANTERA_SUNDIALS_INCLUDE) \
-                 $(CANTERA_BOOST_INCLUDES) $(CANTERA_HDF5_INCLUDES) \
-                 $(CANTERA_EXTRA_INCLUDES)
-
-CANTERA_TOTAL_INCLUDES = $(CANTERA_INCLUDES)
-
-# Add this into the compilation environment to identify the version number
-CANTERA_DEFINES = -DCANTERA_VERSION=@cantera_version@
-
-CANTERA_LIBS=$(CANTERA_CORE_LIBS) \
-             $(CANTERA_EXTRA_LIBDIRS) $(CANTERA_SUNDIALS_LIBS) \
-             $(CANTERA_BLAS_LAPACK_LIBS) $(CANTERA_HDF5_LIBS)
-
-CANTERA_TOTAL_LIBS=$(CANTERA_LIBS)
-
-CANTERA_TOTAL_LIBS_DEP= $(CANTERA_CORE_LIBS_DEP)
-
-CANTERA_FORTRAN_LIBS=$(CANTERA_CORE_FTN) \
-                     $(CANTERA_EXTRA_LIBDIRS) $(CANTERA_SUNDIALS_LIBS) \
-                     $(CANTERA_BLAS_LAPACK_LIBS) $(CANTERA_FORTRAN_SYSLIBS) \
-                     $(CANTERA_HDF5_LIBS)
-
-###############################################################################
-#   END
-###############################################################################
diff --git a/platform/posix/SConscript b/platform/posix/SConscript
index 9f090768ad..c3babf3ad1 100644
--- a/platform/posix/SConscript
+++ b/platform/posix/SConscript
@@ -11,7 +11,6 @@ if env['INSTALL_MANPAGES']:
 
 ### Generate customized scripts ###
 
-# Cantera.mak include file for Makefile projects
 # cantera.pc for use with pkg-config
 
 pc_libs = list(localenv['cantera_libs'])
@@ -19,72 +18,30 @@ pc_libdirs = []
 pc_incdirs = []
 pc_cflags = list(localenv['CXXFLAGS'])
 
-localenv["mak_corelibs"] = " ".join(f"-l{lib}" for lib in localenv["cantera_libs"])
-
-if localenv["package_build"]:
-    # folders outside of conda environment are not transferable
-    localenv["mak_extra_includes"] = ""
-    localenv["mak_extra_libdirs"] = ""
-else:
-    localenv["mak_extra_includes"] = " ".join(
-        f"-I{dir}" for dir in localenv["extra_inc_dirs"])
+if not localenv["package_build"]:
     pc_incdirs.extend(localenv["extra_inc_dirs"])
-
-    localenv["mak_extra_libdirs"] = " ".join(
-        f"-L{dir} -Wl,-rpath,{dir}" for dir in localenv["extra_lib_dirs"])
     pc_libdirs.extend(localenv["extra_lib_dirs"])
 
-localenv["mak_stdlib"] = " ".join(f"-l{lib}" for lib in env["cxx_stdlib"])
-
 if localenv['system_sundials']:
     # Add links to the sundials environment
-    localenv["mak_sundials_libs"] = " ".join(
-        f"-l{lib}" for lib in localenv["sundials_libs"])
     if localenv["sundials_libdir"] and not localenv["package_build"]:
-        localenv["mak_sundials_libdir"] = f"-L{localenv['sundials_libdir']}"
         pc_libdirs.append(localenv['sundials_libdir'])
-    else:
-        localenv['mak_sundials_libdir'] = ''
 
     if localenv["sundials_include"] and not localenv["package_build"]:
-        localenv["mak_sundials_include"] = f"-I{localenv['sundials_include']}"
         pc_incdirs.append(localenv['sundials_include'])
-    else:
-        localenv['mak_sundials_include'] = ''
 
 if localenv["boost_inc_dir"] and not localenv["package_build"]:
-    localenv["mak_boost_include"] = f"-I{localenv['boost_inc_dir']}"
     pc_incdirs.append(localenv['boost_inc_dir'])
-else:
-    localenv['mak_boost_include'] = ''
 
 if localenv["use_hdf5"] and not localenv["package_build"]:
-    localenv["mak_hdf_include"] = f"-I{localenv['hdf_include']}"
     pc_incdirs.append(localenv["hdf_include"])
-    localenv["mak_hdf_libs"] = f"-L{localenv['hdf_libdir']} -lhdf5"
-else:
-    localenv["mak_hdf_include"] = ""
-    localenv["mak_hdf_libs"] = "-lhdf5"
-
-# Handle BLAS/LAPACK linkage
-blas_lapack_libs = " ".join(f"-l{lib}" for lib in localenv["blas_lapack_libs"])
-if localenv["blas_lapack_dir"] and not localenv["package_build"]:
-    localenv["mak_blas_lapack_libs"] = (
-        f"-L{localenv['blas_lapack_dir']} {blas_lapack_libs}")
-else:
-    localenv['mak_blas_lapack_libs'] = blas_lapack_libs
 
 if 'Accelerate' in localenv['FRAMEWORKS']:
-    localenv['mak_blas_lapack_libs'] += ' -framework Accelerate'
     pc_cflags.append('-framework Accelerate')
 
-localenv['mak_threadflags'] = localenv['thread_flags']
 if '-pthread' in localenv['thread_flags']:
-    localenv['mak_fort_threadflags'] = '-lpthread'
     pc_cflags.append('-pthread')
     pc_libs.append('pthread')
-else:
-    localenv['mak_fort_threadflags'] = ''
 
 if localenv["package_build"]:
     # Remove sysroot flags in templated output files. This only applies to the
@@ -96,9 +53,6 @@ if localenv["package_build"]:
     localenv["CCFLAGS"] = compiler_flag_list(localenv["CCFLAGS"], excludes)
     localenv["CXXFLAGS"] = compiler_flag_list(localenv["CXXFLAGS"], excludes)
 
-mak = build(localenv.SubstFile('Cantera.mak', 'Cantera.mak.in'))
-install('$inst_incdir', mak)
-
 # Generate cantera.pc for use with pkg-config
 localenv["pc_prefix"] = localenv["prefix"]
 localenv["pc_libdirs"] = " ".join(f"-L{dir}" for dir in pc_libdirs)
diff --git a/samples/clib/Makefile.in b/samples/clib/Makefile.in
deleted file mode 100644
index f84daa8388..0000000000
--- a/samples/clib/Makefile.in
+++ /dev/null
@@ -1,19 +0,0 @@
-include @make_Cantera_dot_mak@
-
-CC=@CC@
-RM=rm -f
-CFLAGS=@mak_compiler_flags@
-CPPFLAGS=$(CANTERA_INCLUDES)
-LDFLAGS=
-LDLIBS=$(CANTERA_LIBS)
-
-SRCS=@tmpl_sourcename@
-OBJS=$(subst .cpp,.o,$(SRCS))
-
-all: @tmpl_progname@
-
-clean:
-	$(RM) $(OBJS) @tmpl_progname@
-
-dist-clean: clean
-	$(RM) *~
diff --git a/samples/clib/SConscript b/samples/clib/SConscript
index 4a9438803a..0399873bd8 100644
--- a/samples/clib/SConscript
+++ b/samples/clib/SConscript
@@ -49,18 +49,3 @@ for programName, sources in samples:
     localenv['cmake_cantera_libdirs'] = ' '.join(quoted(x) for x in libdirs if x)
     cmakelists = localenv.SubstFile('CMakeLists.txt', 'CMakeLists.txt.in')
     install("$inst_sampledir/clib", cmakelists)
-
-    if localenv["OS"] != "Windows":
-        # Generate Makefile to be installed
-        mak_path = pjoin(localenv["ct_incroot"], "cantera", "Cantera.mak")
-        localenv["mak_compiler_flags"] = " ".join(cc_flags)
-        if " " in mak_path:
-            # There is no reasonable way to handle spaces in Makefile 'include'
-            # statement, so we fall back to using the relative path instead
-            mak_path = relpath(mak_path, pjoin(localenv["ct_sampledir"], "clib"))
-        localenv["make_Cantera_dot_mak"] = mak_path
-
-        localenv["make_target"] = programName
-        localenv["make_sourcefile"] = programName + ".c"
-        makefile = localenv.SubstFile("Makefile", "Makefile.in")
-        install("$inst_sampledir/clib", makefile)
diff --git a/samples/cxx/Makefile.in b/samples/cxx/Makefile.in
deleted file mode 100644
index 54db95cd9c..0000000000
--- a/samples/cxx/Makefile.in
+++ /dev/null
@@ -1,20 +0,0 @@
-include @make_Cantera_dot_mak@
-
-CC=@CC@
-CXX=@CXX@
-RM=rm -f
-CXXFLAGS=@mak_compiler_flags@
-CPPFLAGS=$(CANTERA_INCLUDES)
-LDFLAGS=
-LDLIBS=$(CANTERA_LIBS)
-
-SRCS=@tmpl_sourcename@
-OBJS=$(subst .cpp,.o,$(SRCS))
-
-all: @tmpl_progname@
-
-clean:
-	$(RM) $(OBJS) @tmpl_progname@
-
-dist-clean: clean
-	$(RM) *~
diff --git a/samples/cxx/SConscript b/samples/cxx/SConscript
index bd72779c4e..69be2dd36e 100644
--- a/samples/cxx/SConscript
+++ b/samples/cxx/SConscript
@@ -49,7 +49,7 @@ set(CMAKE_EXE_LINKER_FLAGS ${CMAKE_EXE_LINKER_FLAGS} ${OpenMP_EXE_LINKER_FLAGS})
         buildSample(localenv.Program, pjoin(subdir, name),
                     multi_glob(localenv, subdir, *extensions))
 
-    # Note: These Makefiles and SConstruct files are automatically installed
+    # Note: These CMakeLists.txt and SConstruct files are automatically installed
     # by the "RecursiveInstall" that grabs everything in the cxx directory.
 
     incdirs = [localenv["ct_incroot"]]
@@ -118,16 +118,3 @@ set(CMAKE_EXE_LINKER_FLAGS ${CMAKE_EXE_LINKER_FLAGS} ${OpenMP_EXE_LINKER_FLAGS})
     ## Generate CMakeList.txt files to be installed
     cmakelists = localenv.SubstFile(pjoin(subdir, 'CMakeLists.txt'), 'CMakeLists.txt.in')
     install(pjoin('$inst_sampledir', 'cxx', subdir), cmakelists)
-
-    if localenv["OS"] != "Windows":
-        ## Generate Makefiles to be installed
-        mak_path = pjoin(localenv["ct_incroot"], "cantera", "Cantera.mak")
-        localenv["mak_compiler_flags"] = " ".join(cc_flags)
-        if " " in mak_path:
-            # There is no reasonable way to handle spaces in Makefile 'include'
-            # statement, so we fall back to using the relative path instead
-            mak_path = os.path.relpath(mak_path, pjoin(localenv["ct_sampledir"], "cxx", subdir))
-        localenv["make_Cantera_dot_mak"] = mak_path
-
-        makefile = build(localenv.SubstFile(pjoin(subdir, "Makefile"), "Makefile.in"))
-        install(pjoin("$inst_sampledir", "cxx", subdir), makefile)
diff --git a/samples/f77/Makefile.in b/samples/f77/Makefile.in
deleted file mode 100644
index 2c9dadd953..0000000000
--- a/samples/f77/Makefile.in
+++ /dev/null
@@ -1,22 +0,0 @@
-include @make_Cantera_dot_mak@
-
-FC=@F77@
-RM=rm -f
-FFLAGS=-g
-LDFLAGS=
-LDLIBS=$(CANTERA_FORTRAN_LIBS)
-CXXFLAGS=@mak_compiler_flags@
-CPPFLAGS=$(CANTERA_INCLUDES)
-
-OBJS=isentropic.o demo_ftnlib.o
-
-all: isentropic
-
-isentropic: $(OBJS)
-	$(FC) $(LDFLAGS) -o isentropic $(OBJS) $(LDLIBS) $(CANTERA_LIBS)
-
-clean:
-	$(RM) $(OBJS)
-
-dist-clean: clean
-	$(RM) *~
diff --git a/samples/f77/SConscript b/samples/f77/SConscript
index 5b0d91628c..c367dfdfa6 100644
--- a/samples/f77/SConscript
+++ b/samples/f77/SConscript
@@ -4,8 +4,6 @@ from buildutils import *
 Import('env', 'install', 'buildSample')
 localenv = env.Clone()
 
-localenv['mak_stdlib'] = ['-l' + lib for lib in env['cxx_stdlib']]
-
 # (program name, [source files])
 samples = [("ctlib", ["ctlib.f"]),
            ("demo", ["demo.f"]),
@@ -71,19 +69,5 @@ if localenv["package_build"]:
         localenv["F77"] = "gfortran"
         localenv["CC"] = "gcc"
 
-localenv["mak_compiler_flags"] = " ".join(cc_flags)
-
 sconstruct = localenv.SubstFile('SConstruct', 'SConstruct.in')
 install("$inst_sampledir/f77", sconstruct)
-
-if localenv["OS"] != "Windows":
-    # Generate Makefile to be installed
-    mak_path = pjoin(localenv["ct_incroot"], "cantera", "Cantera.mak")
-    if " " in mak_path:
-        # There is no reasonable way to handle spaces in Makefile 'include'
-        # statement, so we fall back to using the relative path instead
-        mak_path = relpath(mak_path, pjoin(localenv["ct_sampledir"], "f77"))
-    localenv["make_Cantera_dot_mak"] = mak_path
-
-    makefile = localenv.SubstFile("Makefile", "Makefile.in")
-    install("$inst_sampledir/f77", makefile)
diff --git a/samples/f90/Makefile.in b/samples/f90/Makefile.in
deleted file mode 100644
index 2f545e7e1a..0000000000
--- a/samples/f90/Makefile.in
+++ /dev/null
@@ -1,25 +0,0 @@
-include @make_Cantera_dot_mak@
-
-F90=@F90@
-RM=rm -f
-F90FLAGS=-g
-F90MODDIR=$(CANTERA_FORTRAN_MODS)
-LDFLAGS=
-LDLIBS=$(CANTERA_FORTRAN_LIBS)
-
-SRCS=@make_sourcefile@
-OBJS=$(subst .f90,.o,$(SRCS))
-
-all: @make_target@
-
-@make_target@: $(OBJS)
-	$(F90) $(LDFLAGS) -o @make_target@ $(OBJS) $(LDLIBS) $(CANTERA_LIBS)
-
-%.o : %.f90
-	$(F90) -c $< @FORTRANMODDIRPREFIX@$(F90MODDIR) $(F90FLAGS)
-
-clean:
-	$(RM) $(OBJS)
-
-dist-clean: clean
-	$(RM) *~
diff --git a/samples/f90/SConscript b/samples/f90/SConscript
index 690a35351d..dec10eccb0 100644
--- a/samples/f90/SConscript
+++ b/samples/f90/SConscript
@@ -4,8 +4,6 @@ from buildutils import *
 Import('env', 'install', 'buildSample')
 localenv = env.Clone()
 
-localenv['mak_stdlib'] = ['-l' + lib for lib in env['cxx_stdlib']]
-
 # (program name, [source files])
 samples = [('demo', ['demo.f90'])]
 
@@ -51,17 +49,3 @@ for programName, sources in samples:
     localenv['cmake_cantera_libdirs'] = ' '.join(quoted(x) for x in libdirs if x)
     cmakelists = localenv.SubstFile('CMakeLists.txt', 'CMakeLists.txt.in')
     install("$inst_sampledir/f90", cmakelists)
-
-    if localenv["OS"] != "Windows":
-        # Generate Makefile to be installed
-        mak_path = pjoin(localenv["ct_incroot"], "cantera", "Cantera.mak")
-        if " " in mak_path:
-            # There is no reasonable way to handle spaces in Makefile 'include'
-            # statement, so we fall back to using the relative path instead
-            mak_path = relpath(mak_path, pjoin(localenv["ct_sampledir"], "f90"))
-        localenv["make_Cantera_dot_mak"] = mak_path
-
-        localenv["make_target"] = programName
-        localenv["make_sourcefile"] = programName + ".f90"
-        makefile = localenv.SubstFile("Makefile", "Makefile.in")
-        install("$inst_sampledir/f90", makefile)