diff --git a/packages/beacon-node/package.json b/packages/beacon-node/package.json
index 9cc1ef8ecacc..0a63a2ef9ae3 100644
--- a/packages/beacon-node/package.json
+++ b/packages/beacon-node/package.json
@@ -103,6 +103,7 @@
     "@chainsafe/discv5": "^1.4.0",
     "@chainsafe/libp2p-gossipsub": "^4.1.1",
     "@chainsafe/libp2p-noise": "^8.0.0",
+    "@chainsafe/libp2p-yamux": "^3.0.3",
     "@chainsafe/persistent-merkle-tree": "^0.4.2",
     "@chainsafe/snappy-stream": "5.1.1",
     "@chainsafe/ssz": "^0.9.2",
diff --git a/packages/beacon-node/src/network/nodejs/bundle.ts b/packages/beacon-node/src/network/nodejs/bundle.ts
index d933531e6fc8..81dcd4928ea7 100644
--- a/packages/beacon-node/src/network/nodejs/bundle.ts
+++ b/packages/beacon-node/src/network/nodejs/bundle.ts
@@ -6,6 +6,7 @@ import {MulticastDNS} from "@libp2p/mdns";
 import {PeerId} from "@libp2p/interface-peer-id";
 import {Datastore} from "interface-datastore";
 import {Noise} from "@chainsafe/libp2p-noise";
+import {yamux} from "@chainsafe/libp2p-yamux";
 
 export interface ILibp2pOptions {
   peerId: PeerId;
@@ -32,6 +33,9 @@ export async function createNodejsLibp2p(options: ILibp2pOptions): Promise<Libp2
     }
     peerDiscovery.push(new MulticastDNS());
   }
+
+  const yamuxInstance = yamux()();
+
   return await createLibp2p({
     peerId: options.peerId,
     addresses: {
@@ -40,7 +44,12 @@ export async function createNodejsLibp2p(options: ILibp2pOptions): Promise<Libp2
     },
     connectionEncryption: [new Noise()],
     transports: [new TCP()],
-    streamMuxers: [new Mplex({maxInboundStreams: 256})],
+    streamMuxers: [
+      //
+      new Mplex({maxInboundStreams: 256}),
+      // Cast because yamux.StreamMuxerFactory is different than libp2p.StreamMuxerFactory
+      yamuxInstance as Mplex,
+    ],
     peerDiscovery,
     metrics: {
       // temporarily disable since there is a performance issue with it
diff --git a/yarn.lock b/yarn.lock
index 11c1f4b40b53..fad5230381bb 100644
--- a/yarn.lock
+++ b/yarn.lock
@@ -572,6 +572,24 @@
     uint8arraylist "^2.3.2"
     uint8arrays "^3.1.0"
 
+"@chainsafe/libp2p-yamux@^3.0.3":
+  version "3.0.3"
+  resolved "https://registry.yarnpkg.com/@chainsafe/libp2p-yamux/-/libp2p-yamux-3.0.3.tgz#cad939cb5588c3dacbecaea83f54399fb374becb"
+  integrity sha512-PR/X8sXlcnbsJ4l87GdfSUMQ8pAoKkAkST9ecJkBa7fr7QLvuc4xzEBm9tgj8uqg+yxmLA1wz1X4qfKy2u3RLg==
+  dependencies:
+    "@libp2p/interface-connection" "^3.0.1"
+    "@libp2p/interface-stream-muxer" "^3.0.0"
+    "@libp2p/logger" "^2.0.1"
+    abortable-iterator "^4.0.2"
+    any-signal "^3.0.1"
+    err-code "^3.0.1"
+    iso-random-stream "^2.0.2"
+    it-pipe "^2.0.4"
+    it-pushable "^3.1.0"
+    multiformats "^10.0.0"
+    uint8arraylist "^2.3.2"
+    uint8arrays "^4.0.2"
+
 "@chainsafe/persistent-merkle-tree@^0.4.2":
   version "0.4.2"
   resolved "https://registry.yarnpkg.com/@chainsafe/persistent-merkle-tree/-/persistent-merkle-tree-0.4.2.tgz#4c9ee80cc57cd3be7208d98c40014ad38f36f7ff"
@@ -2028,6 +2046,15 @@
     "@libp2p/interfaces" "^3.0.0"
     it-stream-types "^1.0.4"
 
+"@libp2p/interface-stream-muxer@^3.0.0":
+  version "3.0.1"
+  resolved "https://registry.yarnpkg.com/@libp2p/interface-stream-muxer/-/interface-stream-muxer-3.0.1.tgz#d7724cb38800dc4843c476118ee0ce24a190526f"
+  integrity sha512-HlIZFMMSYTKOKn5VBw8UHQ5qya6oWSqpP2ygtSoB/nbBcC/3mv/4cbvozJUAGrOrDz01YY3QOB2LJ6R1b0EWCQ==
+  dependencies:
+    "@libp2p/interface-connection" "^3.0.0"
+    "@libp2p/interfaces" "^3.0.0"
+    it-stream-types "^1.0.4"
+
 "@libp2p/interface-transport@^1.0.3", "@libp2p/interface-transport@^1.0.4":
   version "1.0.4"
   resolved "https://registry.yarnpkg.com/@libp2p/interface-transport/-/interface-transport-1.0.4.tgz#b36206b629878462bc6a1b8034998af02f810c24"
@@ -4105,6 +4132,11 @@ any-signal@^3.0.0:
   resolved "https://registry.npmjs.org/any-signal/-/any-signal-3.0.0.tgz"
   integrity sha512-l1H1GEkGGIXVGfCtvq8N68YI7gHajmfzRdKhmb8sGyAQpLCblirLa8eB09j4uKaiwe7vodAChocUf7AT3mYq5g==
 
+any-signal@^3.0.1:
+  version "3.0.1"
+  resolved "https://registry.yarnpkg.com/any-signal/-/any-signal-3.0.1.tgz#49cae34368187a3472e31de28fb5cb1430caa9a6"
+  integrity sha512-xgZgJtKEa9YmDqXodIgl7Fl1C8yNXr8w6gXjqK3LW4GcEiYT+6AQfJSE/8SPsEpLLmcvbv8YU+qet94UewHxqg==
+
 anymatch@~3.1.2:
   version "3.1.2"
   resolved "https://registry.npmjs.org/anymatch/-/anymatch-3.1.2.tgz"
@@ -8238,6 +8270,14 @@ isexe@^2.0.0:
   resolved "https://registry.yarnpkg.com/isexe/-/isexe-2.0.0.tgz#e8fbf374dc556ff8947a10dcb0572d633f2cfa10"
   integrity sha512-RHxMLp9lnKHGHRng9QFhRCMbYAcVpn69smSGcq3f36xjgVVWThj4qqLbTLlq7Ssj8B+fIQ1EuCEGI2lKsyQeIw==
 
+iso-random-stream@^2.0.2:
+  version "2.0.2"
+  resolved "https://registry.yarnpkg.com/iso-random-stream/-/iso-random-stream-2.0.2.tgz#a24f77c34cfdad9d398707d522a6a0cc640ff27d"
+  integrity sha512-yJvs+Nnelic1L2vH2JzWvvPQFA4r7kSTnpST/+LkAQjSz0hos2oqLD+qIVi9Qk38Hoe7mNDt3j0S27R58MVjLQ==
+  dependencies:
+    events "^3.3.0"
+    readable-stream "^3.4.0"
+
 isobject@^3.0.1:
   version "3.0.1"
   resolved "https://registry.yarnpkg.com/isobject/-/isobject-3.0.1.tgz#4e431e92b11a9731636aa1f9c8d1ccbcfdab78df"