diff --git a/containers/bwa-mem2/Dockerfile b/containers/bwa-mem2/Dockerfile
index 1a543f8d7..d7cc50649 100644
--- a/containers/bwa-mem2/Dockerfile
+++ b/containers/bwa-mem2/Dockerfile
@@ -5,9 +5,9 @@ FROM ubuntu:bionic
 ################## METADATA ######################
 
 LABEL base_image="ubuntu:bionic"
-LABEL version="2"
+LABEL version="3"
 LABEL software="bwa-mem2"
-LABEL software.version="2.2"
+LABEL software.version="2.2.1"
 LABEL extra.binaries="bwa-mem2"
 LABEL maintainer="Clinical-Genomics/MIP"
 
@@ -25,7 +25,7 @@ RUN apt-get update && \
 WORKDIR /app
 
 ## Install bwa-mem2
-RUN curl -L https://github.com/bwa-mem2/bwa-mem2/releases/download/v2.2/bwa-mem2-2.2_x64-linux.tar.bz2 \
+RUN curl -L https://github.com/bwa-mem2/bwa-mem2/releases/download/v2.2.1/bwa-mem2-2.2.1_x64-linux.tar.bz2 \
   | tar jxf -
 
-ENV PATH=/app/bwa-mem2-2.2_x64-linux:${PATH}
\ No newline at end of file
+ENV PATH=/app/bwa-mem2-2.2.1_x64-linux:${PATH}
\ No newline at end of file
diff --git a/t/data/test_data/miptest_install_config.yaml b/t/data/test_data/miptest_install_config.yaml
index f732df780..7fd6a3dec 100644
--- a/t/data/test_data/miptest_install_config.yaml
+++ b/t/data/test_data/miptest_install_config.yaml
@@ -33,7 +33,7 @@ container:
   bwa-mem2:
     executable:
       bwa-mem2:
-    uri: docker.io/clinicalgenomics/bwa-mem2:2.2
+    uri: docker.io/clinicalgenomics/bwa-mem2:2.2.1
   bedtools:
     executable:
       bedtools:
diff --git a/templates/mip_install_config.yaml b/templates/mip_install_config.yaml
index 250602fd5..e5a7aa4ec 100644
--- a/templates/mip_install_config.yaml
+++ b/templates/mip_install_config.yaml
@@ -25,7 +25,7 @@ container:
   bwa-mem2:
     executable:
       bwa-mem2:
-    uri: docker.io/clinicalgenomics/bwa-mem2:2.2
+    uri: docker.io/clinicalgenomics/bwa-mem2:2.2.1
   bedtools:
     executable:
       bedtools: