diff --git a/profiler/internal/pprofutils/delta.go b/profiler/internal/pprofutils/delta.go
index 263668bd9c..f81fa169aa 100644
--- a/profiler/internal/pprofutils/delta.go
+++ b/profiler/internal/pprofutils/delta.go
@@ -17,8 +17,6 @@ type Delta struct {
 	// SampleTypes limits the delta calcultion to the given sample types. Other
 	// sample types will retain the values of profile b. The defined sample types
 	// must exist in the profile, otherwise derivation will fail with an error.
-	// If the slice is empty, all sample types are subject to delta profile
-	// derivation.
 	//
 	// The use case for this for this is to deal with the heap profile which
 	// contains alloc and inuse sample types, but delta profiling makes no sense
@@ -30,21 +28,12 @@ type Delta struct {
 // profile. Samples that end up with a delta of 0 are dropped. WARNING: Profile
 // a will be mutated by this function. You should pass a copy if that's
 // undesirable.
-//
-// Other profiles that should be merged into the resulting profile can be passed
-// through the extra parameter.
-func (d Delta) Convert(a, b *profile.Profile, extra ...*profile.Profile) (*profile.Profile, error) {
+func (d Delta) Convert(a, b *profile.Profile) (*profile.Profile, error) {
 	ratios := make([]float64, len(a.SampleType))
 
 	found := 0
 	for i, st := range a.SampleType {
-		// Empty c.SampleTypes means we calculate the delta for every st
-		if len(d.SampleTypes) == 0 {
-			ratios[i] = -1
-			continue
-		}
-
-		// Otherwise we only calcuate the delta for any st that is listed in
+		// We only calcuate the delta for any st that is listed in
 		// c.SampleTypes. st's not listed in there will default to ratio 0, which
 		// means we delete them from pa, so only the pb values remain in the final
 		// profile.
@@ -61,10 +50,7 @@ func (d Delta) Convert(a, b *profile.Profile, extra ...*profile.Profile) (*profi
 
 	a.ScaleN(ratios)
 
-	profiles := make([]*profile.Profile, 0, 2+len(extra))
-	profiles = append(profiles, a, b)
-	profiles = append(profiles, extra...)
-	delta, err := profile.Merge(profiles)
+	delta, err := profile.Merge([]*profile.Profile{a, b})
 	if err != nil {
 		return nil, err
 	}
diff --git a/profiler/internal/pprofutils/delta_test.go b/profiler/internal/pprofutils/delta_test.go
index c922aa2847..9fdc588718 100644
--- a/profiler/internal/pprofutils/delta_test.go
+++ b/profiler/internal/pprofutils/delta_test.go
@@ -18,6 +18,7 @@ func TestDelta(t *testing.T) {
 		var deltaText bytes.Buffer
 
 		profA, err := Text{}.Convert(strings.NewReader(strings.TrimSpace(`
+x/count
 main;foo 5
 main;foo;bar 3
 main;foobar 4
@@ -25,13 +26,14 @@ main;foobar 4
 		require.NoError(t, err)
 
 		profB, err := Text{}.Convert(strings.NewReader(strings.TrimSpace(`
+x/count
 main;foo 8
 main;foo;bar 3
 main;foobar 5
 `)))
 		require.NoError(t, err)
 
-		delta, err := Delta{}.Convert(profA, profB)
+		delta, err := Delta{SampleTypes: []ValueType{{Type: "x", Unit: "count"}}}.Convert(profA, profB)
 		require.NoError(t, err)
 
 		require.NoError(t, Protobuf{}.Convert(delta, &deltaText))
diff --git a/profiler/profile.go b/profiler/profile.go
index c939569af7..424753e1c0 100644
--- a/profiler/profile.go
+++ b/profiler/profile.go
@@ -64,12 +64,13 @@ type profileType struct {
 	// this isn't done due to idiosyncratic filename used by the
 	// GoroutineProfile.
 	Filename string
-	// SupportsDelta indicates whether delta profiles can be computed for
-	// this profile type, which is used to determine the final filename
-	SupportsDelta bool
 	// Collect collects the given profile and returns the data for it. Most
 	// profiles will be in pprof format, i.e. gzip compressed proto buf data.
 	Collect func(p *profiler) ([]byte, error)
+	// DeltaValues identifies which values in profile samples should be modified
+	// when delta profiling is enabled. Empty DeltaValues means delta profiling is
+	// not supported for this profile type
+	DeltaValues []pprofutils.ValueType
 }
 
 // profileTypes maps every ProfileType to its implementation.
@@ -109,28 +110,34 @@ var profileTypes = map[ProfileType]profileType{
 	HeapProfile: {
 		Name:     "heap",
 		Filename: "heap.pprof",
-		Collect: collectGenericProfile("heap", HeapProfile, &pprofutils.Delta{SampleTypes: []pprofutils.ValueType{
+		Collect:  collectGenericProfile("heap", HeapProfile),
+		DeltaValues: []pprofutils.ValueType{
 			{Type: "alloc_objects", Unit: "count"},
 			{Type: "alloc_space", Unit: "bytes"},
-		}}),
-		SupportsDelta: true,
+		},
 	},
 	MutexProfile: {
-		Name:          "mutex",
-		Filename:      "mutex.pprof",
-		Collect:       collectGenericProfile("mutex", MutexProfile, &pprofutils.Delta{}),
-		SupportsDelta: true,
+		Name:     "mutex",
+		Filename: "mutex.pprof",
+		Collect:  collectGenericProfile("mutex", MutexProfile),
+		DeltaValues: []pprofutils.ValueType{
+			{Type: "contentions", Unit: "count"},
+			{Type: "delay", Unit: "nanoseconds"},
+		},
 	},
 	BlockProfile: {
-		Name:          "block",
-		Filename:      "block.pprof",
-		Collect:       collectGenericProfile("block", BlockProfile, &pprofutils.Delta{}),
-		SupportsDelta: true,
+		Name:     "block",
+		Filename: "block.pprof",
+		Collect:  collectGenericProfile("block", BlockProfile),
+		DeltaValues: []pprofutils.ValueType{
+			{Type: "contentions", Unit: "count"},
+			{Type: "delay", Unit: "nanoseconds"},
+		},
 	},
 	GoroutineProfile: {
 		Name:     "goroutine",
 		Filename: "goroutines.pprof",
-		Collect:  collectGenericProfile("goroutine", GoroutineProfile, nil),
+		Collect:  collectGenericProfile("goroutine", GoroutineProfile),
 	},
 	expGoroutineWaitProfile: {
 		Name:     "goroutinewait",
@@ -166,9 +173,9 @@ var profileTypes = map[ProfileType]profileType{
 	},
 }
 
-func collectGenericProfile(name string, pt ProfileType, delta *pprofutils.Delta) func(p *profiler) ([]byte, error) {
+func collectGenericProfile(name string, pt ProfileType) func(p *profiler) ([]byte, error) {
 	return func(p *profiler) ([]byte, error) {
-		var extra []*pprofile.Profile
+		var extra *pprofile.Profile
 		cAlloc, ok := extensions.GetCAllocationProfiler()
 		switch {
 		case ok && p.cfg.cmemprofEnabled && p.cfg.deltaProfiles && pt == HeapProfile:
@@ -183,7 +190,7 @@ func collectGenericProfile(name string, pt ProfileType, delta *pprofutils.Delta)
 			p.interruptibleSleep(p.cfg.period)
 			profile, err := cAlloc.Stop()
 			if err == nil {
-				extra = append(extra, profile)
+				extra = profile
 			}
 		default:
 			// In all cases, sleep until the end of the profile
@@ -195,18 +202,34 @@ func collectGenericProfile(name string, pt ProfileType, delta *pprofutils.Delta)
 		var buf bytes.Buffer
 		err := p.lookupProfile(name, &buf, 0)
 		data := buf.Bytes()
-		if delta == nil || !p.cfg.deltaProfiles {
+		dp, ok := p.deltas[pt]
+		if !ok || !p.cfg.deltaProfiles {
 			return data, err
 		}
 
 		start := time.Now()
-		delta, err := p.deltaProfile(name, delta, data, extra...)
+		delta, err := dp.Delta(data)
+		if err == nil && extra != nil {
+			extended, err := pprofile.ParseData(delta)
+			if err != nil {
+				return nil, err
+			}
+			extended, err = pprofile.Merge([]*pprofile.Profile{extended, extra})
+			if err != nil {
+				return nil, err
+			}
+			buf.Reset()
+			if err := extended.Write(&buf); err != nil {
+				return nil, err
+			}
+			delta = buf.Bytes()
+		}
 		tags := append(p.cfg.tags.Slice(), fmt.Sprintf("profile_type:%s", name))
 		p.cfg.statsd.Timing("datadog.profiling.go.delta_time", time.Since(start), tags, 1)
 		if err != nil {
 			return nil, fmt.Errorf("delta profile error: %s", err)
 		}
-		return delta.data, err
+		return delta, err
 	}
 }
 
@@ -273,25 +296,37 @@ func (p *profiler) runProfile(pt ProfileType) ([]*profile, error) {
 	tags := append(p.cfg.tags.Slice(), pt.Tag())
 	filename := t.Filename
 	// TODO(fg): Consider making Collect() return the filename.
-	if p.cfg.deltaProfiles && t.SupportsDelta {
+	if p.cfg.deltaProfiles && len(t.DeltaValues) > 0 {
 		filename = "delta-" + filename
 	}
 	p.cfg.statsd.Timing("datadog.profiling.go.collect_time", end.Sub(start), tags, 1)
 	return []*profile{{name: filename, data: data}}, nil
 }
 
-// deltaProfile derives the delta profile between curData and the previous
-// profile. If extra profiles are provided, they will be merged into the final
-// profile after computing the delta profile.
-func (p *profiler) deltaProfile(name string, delta *pprofutils.Delta, curData []byte, extra ...*pprofile.Profile) (*profile, error) {
+type deltaProfiler struct {
+	delta pprofutils.Delta
+	prev  *pprofile.Profile
+}
+
+// newDeltaProfiler returns an initialized deltaProfiler. If value types
+// are given (e.g. "alloc_space", "alloc_objects"), only those values will have
+// deltas computed. Otherwise, deltas will be computed for every value.
+func newDeltaProfiler(v ...pprofutils.ValueType) *deltaProfiler {
+	return &deltaProfiler{
+		delta: pprofutils.Delta{SampleTypes: v},
+	}
+}
+
+// Delta derives the delta profile between curData and the profile passed to the
+// previous call to Delta. The first call to Delta will return the profile
+// unchanged.
+func (d *deltaProfiler) Delta(curData []byte) ([]byte, error) {
 	curProf, err := pprofile.ParseData(curData)
 	if err != nil {
 		return nil, fmt.Errorf("delta prof parse: %v", err)
 	}
 	var deltaData []byte
-	p.mu.Lock()
-	prevProf := p.prev[name]
-	p.mu.Unlock()
+	prevProf := d.prev
 	if prevProf == nil {
 		// First time deltaProfile gets called for a type, there is no prevProf. In
 		// this case we emit the current profile as a delta profile.
@@ -301,7 +336,7 @@ func (p *profiler) deltaProfile(name string, delta *pprofutils.Delta, curData []
 		// Unfortunately the core implementation isn't resuable via a API, so we do
 		// our own delta calculation below.
 		// https://github.com/golang/go/commit/2ff1e3ebf5de77325c0e96a6c2a229656fc7be50#diff-94594f8f13448da956b02997e50ca5a156b65085993e23bbfdda222da6508258R303-R304
-		deltaProf, err := delta.Convert(prevProf, curProf, extra...)
+		deltaProf, err := d.delta.Convert(prevProf, curProf)
 		if err != nil {
 			return nil, fmt.Errorf("delta prof merge: %v", err)
 		}
@@ -318,10 +353,8 @@ func (p *profiler) deltaProfile(name string, delta *pprofutils.Delta, curData []
 	}
 	// Keep the most recent profiles in memory for future diffing. This needs to
 	// be taken into account when enforcing memory limits going forward.
-	p.mu.Lock()
-	p.prev[name] = curProf
-	p.mu.Unlock()
-	return &profile{data: deltaData}, nil
+	d.prev = curProf
+	return deltaData, nil
 }
 
 func goroutineDebug2ToPprof(r io.Reader, w io.Writer, t time.Time) (err error) {
diff --git a/profiler/profile_test.go b/profiler/profile_test.go
index abe2caf25e..ba25f82f9d 100644
--- a/profiler/profile_test.go
+++ b/profiler/profile_test.go
@@ -43,29 +43,29 @@ func TestRunProfile(t *testing.T) {
 				Prof1: textProfile{
 					Time: timeA,
 					Text: `
-stuff/count
-main 3
-main;bar 2
-main;foo 5
+contentions/count delay/nanoseconds
+main 3 1
+main;bar 2 1
+main;foo 5 1
 `,
 				},
 				Prof2: textProfile{
 					Time: timeB,
 					Text: `
-stuff/count
-main 4
-main;bar 2
-main;foo 8
-main;foobar 7
+contentions/count delay/nanoseconds
+main 4 1
+main;bar 2 1
+main;foo 8 1
+main;foobar 7 1
 `,
 				},
 				WantDelta: textProfile{
 					Time: timeA,
 					Text: `
-stuff/count
-main;foobar 7
-main;foo 3
-main 1
+contentions/count delay/nanoseconds
+main;foobar 7 1
+main;foo 3 0
+main 1 0
 `,
 				},
 				WantDuration: deltaPeriod,
@@ -115,7 +115,7 @@ main;bar 0 0 8 16
 				// followed by prof2 when calling runProfile().
 				deltaProfiler := func(prof1, prof2 []byte, opts ...Option) (*profiler, func()) {
 					returnProfs := [][]byte{prof1, prof2}
-					opts = append(opts, WithPeriod(5*time.Millisecond))
+					opts = append(opts, WithPeriod(5*time.Millisecond), WithProfileTypes(HeapProfile, MutexProfile, BlockProfile))
 					p, err := unstartedProfiler(opts...)
 					p.testHooks.lookupProfile = func(_ string, w io.Writer, _ int) error {
 						_, err := w.Write(returnProfs[0])
diff --git a/profiler/profiler.go b/profiler/profiler.go
index a9d6adab42..bb0610216e 100644
--- a/profiler/profiler.go
+++ b/profiler/profiler.go
@@ -20,8 +20,6 @@ import (
 	"gopkg.in/DataDog/dd-trace-go.v1/internal"
 	"gopkg.in/DataDog/dd-trace-go.v1/internal/log"
 	"gopkg.in/DataDog/dd-trace-go.v1/internal/telemetry"
-
-	pprofile "github.com/google/pprof/profile"
 )
 
 // outChannelSize specifies the size of the profile output channel.
@@ -64,15 +62,14 @@ func Stop() {
 // profiler collects and sends preset profiles to the Datadog API at a given frequency
 // using a given configuration.
 type profiler struct {
-	mu              sync.Mutex
-	cfg             *config                      // profile configuration
-	out             chan batch                   // upload queue
-	uploadFunc      func(batch) error            // defaults to (*profiler).upload; replaced in tests
-	exit            chan struct{}                // exit signals the profiler to stop; it is closed after stopping
-	stopOnce        sync.Once                    // stopOnce ensures the profiler is stopped exactly once.
-	wg              sync.WaitGroup               // wg waits for all goroutines to exit when stopping.
-	met             *metrics                     // metric collector state
-	prev            map[string]*pprofile.Profile // previous collection results for delta profiling
+	cfg             *config           // profile configuration
+	out             chan batch        // upload queue
+	uploadFunc      func(batch) error // defaults to (*profiler).upload; replaced in tests
+	exit            chan struct{}     // exit signals the profiler to stop; it is closed after stopping
+	stopOnce        sync.Once         // stopOnce ensures the profiler is stopped exactly once.
+	wg              sync.WaitGroup    // wg waits for all goroutines to exit when stopping.
+	met             *metrics          // metric collector state
+	deltas          map[ProfileType]*deltaProfiler
 	telemetry       *telemetry.Client
 	seq             uint64         // seq is the value of the profile_seq tag
 	pendingProfiles sync.WaitGroup // signal that profile collection is done, for stopping CPU profiling
@@ -182,11 +179,16 @@ func newProfiler(opts ...Option) (*profiler, error) {
 	}
 
 	p := profiler{
-		cfg:  cfg,
-		out:  make(chan batch, outChannelSize),
-		exit: make(chan struct{}),
-		met:  newMetrics(),
-		prev: make(map[string]*pprofile.Profile),
+		cfg:    cfg,
+		out:    make(chan batch, outChannelSize),
+		exit:   make(chan struct{}),
+		met:    newMetrics(),
+		deltas: make(map[ProfileType]*deltaProfiler),
+	}
+	for pt := range cfg.types {
+		if d := profileTypes[pt].DeltaValues; len(d) > 0 {
+			p.deltas[pt] = newDeltaProfiler(d...)
+		}
 	}
 	p.uploadFunc = p.upload
 	p.telemetry = &telemetry.Client{