diff --git a/ddtrace/ext/aws.py b/ddtrace/ext/aws.py
index b92fe1045f2..d8f33876ae0 100644
--- a/ddtrace/ext/aws.py
+++ b/ddtrace/ext/aws.py
@@ -14,6 +14,7 @@
 EXCLUDED_ENDPOINT = frozenset({"kms", "sts", "sns", "kinesis", "events"})
 EXCLUDED_ENDPOINT_TAGS = {
     "firehose": frozenset({"params.Records"}),
+    "secretsmanager": frozenset({"params.SecretString", "params.SecretBinary"}),
 }
 
 
diff --git a/releasenotes/notes/fix-botocore-omit-secretstring-secretbinary-743a1780c86db384.yaml b/releasenotes/notes/fix-botocore-omit-secretstring-secretbinary-743a1780c86db384.yaml
new file mode 100644
index 00000000000..29d4c105263
--- /dev/null
+++ b/releasenotes/notes/fix-botocore-omit-secretstring-secretbinary-743a1780c86db384.yaml
@@ -0,0 +1,4 @@
+---
+fixes:
+  - |
+    botocore: omit ``SecretBinary`` and ``SecretString`` from span metadata for calls to Secrets Manager.
diff --git a/tests/contrib/botocore/test.py b/tests/contrib/botocore/test.py
index 5853b52762c..06c5635f2d1 100644
--- a/tests/contrib/botocore/test.py
+++ b/tests/contrib/botocore/test.py
@@ -27,6 +27,7 @@
 from ddtrace.constants import ANALYTICS_SAMPLE_RATE_KEY
 from ddtrace.contrib.botocore.patch import patch
 from ddtrace.contrib.botocore.patch import unpatch
+from ddtrace.internal.compat import PY2
 from ddtrace.internal.compat import stringify
 from ddtrace.internal.utils.version import parse_version
 from ddtrace.propagation.http import HTTP_HEADER_PARENT_ID
@@ -1634,3 +1635,53 @@ def test_kinesis_put_records_base64_exceeds_max_size(self):
             assert "_datadog" not in headers
 
         client.delete_stream(StreamName=stream_name)
+
+    @unittest.skipIf(PY2, "Skipping for Python 2.7 since older moto doesn't support secretsmanager")
+    def test_secretsmanager(self):
+        from moto import mock_secretsmanager
+
+        with mock_secretsmanager():
+            client = self.session.create_client("secretsmanager", region_name="us-east-1")
+            Pin(service=self.TEST_SERVICE, tracer=self.tracer).onto(client)
+
+            resp = client.create_secret(Name="/my/secrets", SecretString="supersecret-string")
+            assert resp["ResponseMetadata"]["HTTPStatusCode"] == 200
+
+            spans = self.get_spans()
+            assert len(spans) == 1
+            span = spans[0]
+
+            assert span.name == "secretsmanager.command"
+            assert span.resource == "secretsmanager.createsecret"
+            assert span.get_tag("params.Name") == "/my/secrets"
+            assert span.get_tag("aws.operation") == "CreateSecret"
+            assert span.get_tag("aws.region") == "us-east-1"
+            assert span.get_tag("aws.agent") == "botocore"
+            assert span.get_tag("http.status_code") == "200"
+            assert span.get_tag("params.SecretString") is None
+            assert span.get_tag("params.SecretBinary") is None
+
+    @unittest.skipIf(PY2, "Skipping for Python 2.7 since older moto doesn't support secretsmanager")
+    def test_secretsmanager_binary(self):
+        from moto import mock_secretsmanager
+
+        with mock_secretsmanager():
+            client = self.session.create_client("secretsmanager", region_name="us-east-1")
+            Pin(service=self.TEST_SERVICE, tracer=self.tracer).onto(client)
+
+            resp = client.create_secret(Name="/my/secrets", SecretBinary=b"supersecret-binary")
+            assert resp["ResponseMetadata"]["HTTPStatusCode"] == 200
+
+            spans = self.get_spans()
+            assert len(spans) == 1
+            span = spans[0]
+
+            assert span.name == "secretsmanager.command"
+            assert span.resource == "secretsmanager.createsecret"
+            assert span.get_tag("params.Name") == "/my/secrets"
+            assert span.get_tag("aws.operation") == "CreateSecret"
+            assert span.get_tag("aws.region") == "us-east-1"
+            assert span.get_tag("aws.agent") == "botocore"
+            assert span.get_tag("http.status_code") == "200"
+            assert span.get_tag("params.SecretString") is None
+            assert span.get_tag("params.SecretBinary") is None