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<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.obolibrary.org/obo/doid/imports/hp_import.owl#"
xml:base="http://purl.obolibrary.org/obo/doid/imports/hp_import.owl"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:obo="http://purl.obolibrary.org/obo/">
<owl:Ontology rdf:about="http://purl.obolibrary.org/obo/doid/imports/hp_import.owl"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/IAO_0000115 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">definition</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#id -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
<!-- http://www.w3.org/2000/01/rdf-schema#label -->
<owl:AnnotationProperty rdf:about="http://www.w3.org/2000/01/rdf-schema#label"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/HP_0000002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000002">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001507"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Deviation from the norm of height with respect to that which is expected according to age and gender norms.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000002</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of body height</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004299"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Protrusion of the contents of the abdominal cavity through the inguinal canal.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000023</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Inguinal hernia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000032 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000032">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000811"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010461"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of male external genitalia.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000032</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of male external genitalia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000035">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000032"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An anomaly of the testicle (the male gonad).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000035</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the testis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000037">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000032"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hermaphroditism refers to a discrepancy between the morphology of the gonads and that of the external genitalia. In male pseudohermaphroditism, the genotype is male (XY) and the external genitalia are imcompletely virilized, ambiguous, or complete female. If gonads are present, they are testes.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000037</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Male pseudohermaphroditism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0003241"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Underdevelopment of part or all of the male external reproductive organs (which include the penis, the scrotum and the urethra).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000050</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hypoplastic male external genitalia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000077 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000077">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010935"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the kidney.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000077</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the kidney</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000078 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000078">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000119"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the genital system.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000078</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the genital system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000079 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000079">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000119"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the urinary system.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000079</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the urinary system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000083 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000083">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012211"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A reduction in the level of performance of the kidneys in areas of function comprising the concentration of urine, removal of wastes, the maintenance of electrolyte balance, homeostasis of blood pressure, and calcium metabolism.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000083</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Renal insufficiency</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000090 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000090">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0100957"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Presence of cysts at the corticomedullary junction of the kidney in combination with tubulointerstitial fibrosis.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000090</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Nephronophthisis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000095 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000095">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012575"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0031263"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A structural anomaly of the glomerulus.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000095</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of renal glomerulus morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000098 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000098">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000002"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A height above that which is expected according to age and gender norms.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000098</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tall stature</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000118 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000118">
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A phenotypic abnormality.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000118</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phenotypic abnormality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000119 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000119">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The presence of any abnormality of the genitourinary system.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000119</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the genitourinary system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000152 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000152">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of head and neck.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000152</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of head or neck</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000153 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000153">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000271"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the mouth.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000153</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the mouth</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000159 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000159">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000153"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the lip.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000159</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the lip</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000163 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000163">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000153"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the oral cavity, i.e., the opening or hollow part of the mouth.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000163</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the oral cavity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000164 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000164">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000163"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any abnormality of the teeth.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000164</oboInOwl:id>
<rdfs:label>Abnormality of the dentition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000177 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000177">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000159"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the upper lip.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000177</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of upper lip</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000219 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000219">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000233"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011339"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Height of the vermilion of the upper lip in the midline more than 2 SD below the mean. Alternatively, an apparently reduced height of the vermilion of the upper lip in the frontal view (subjective).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000219</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Thin upper lip vermilion</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000233 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000233">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000159"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reduced width of the skin of vermilion border region of upper lip.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000233</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Thin vermilion border</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000234 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000234">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000152"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the head.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000234</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the head</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000235 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000235">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002683"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any abnormality of the fontanelles (the regions covered by a thick membrane that normally ossify in the first two years of life) or the cranial sutures (the fibrous joints in which the articulating bones or cartilages of the skull are connected by sutural ligaments ).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000235</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the fontanelles or cranial sutures</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000240 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000240">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000929"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any abnormality of the size of the skull.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000240</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of skull size</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000252 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000252">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0007364"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0040195"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Occipito-frontal (head) circumference (OFC) less than -3 standard deviations compared to appropriate, age matched, normal standards (Ross JJ, Frias JL 1977, PMID:9683597). Alternatively, decreased size of the cranium.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000252</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Microcephaly</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000264 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000264">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000929"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the mastoid process, which is the conical prominence projecting from the undersurface of the mastoid portion of the temporal bone.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000264</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the mastoid</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000265 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000265">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000264"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000265</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mastoiditis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000271 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000271">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000234"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the face.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000271</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the face</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000272 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000272">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012369"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Underdevelopment of the malar prominence of the jugal bone (zygomatic bone in mammals), appreciated in profile, frontal view, and/or by palpation.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000272</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Malar flattening</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000274 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000274">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001999"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A face that is short (HP:0011219) and narrow (HP:0000275).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000274</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Small face</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000275 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000275">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000274"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bizygomatic (upper face) and bigonial (lower face) width are both more than 2 standard deviations below the mean (objective); or, an apparent reduction in the width of the upper and lower face (subjective).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000275</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Narrow face</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000277 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000277">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0030791"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any abnormality of the mandible, the bone of the lower jaw.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000277</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the mandible</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000278 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000278">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000277"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality in which the mandible is mislocalised posteriorly.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000278</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Retrognathia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000290 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000290">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000271"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An anomaly of the forehead.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000290</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the forehead</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000309 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000309">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000271"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An anomaly of the midface, which is a region and not an anatomical term. It extends, superiorly, from the inferior orbital margin to, inferiorly, the level of nasal base. It is formed by the maxilla (upper jaw) and zygoma and cheeks and malar region. Traditionally, the nose and premaxilla are not included in the midface.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000309</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the midface</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000347 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000347">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0009118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Developmental hypoplasia of the mandible.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000347</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Micrognathia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000359 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000359">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0031703"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the inner ear.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000359</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the inner ear</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000364 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000364">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0031704"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the sensory perception of sound.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000364</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hearing abnormality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000365 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000365">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000364"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A decreased magnitude of the sensory perception of sound.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000365</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hearing impairment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000366 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000366">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000271"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the nose.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000366</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the nose</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000370 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000370">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0031703"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the middle ear.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000370</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the middle ear</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000405 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000405">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000365"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011452"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of vibrational conductance of sound to the inner ear leading to impairment of sensory perception of sound.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000405</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Conductive hearing impairment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000407 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000407">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000365"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011389"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A type of hearing impairment in one or both ears related to an abnormal functionality of the cochlear nerve.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000407</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sensorineural hearing impairment</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000478 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000478">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any abnormality of the eye, including location, spacing, and intraocular abnormalities.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000478</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the eye</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000479 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000479">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001098"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A structural abnormality of the retina.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000479</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal retinal morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000504 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000504">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012373"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of eyesight (visual perception).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000504</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of vision</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000517 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000517">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004328"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the lens.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000517</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the lens</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000518 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000518">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000517"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A cataract is an opacity or clouding that develops in the crystalline lens of the eye or in its capsule.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000518</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Cataract</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000525 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000525">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000553"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004328"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the iris, which is the pigmented muscular tissue between the cornea and the lens, that is perforated by an opening called the pupil.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000525</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality iris morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000526 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000526">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0008053"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Congenital absence of the iris.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000526</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Aniridia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000532 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000532">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000479"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000610"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the choroid and retina.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000532</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal chorioretinal morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000546 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000546">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000479"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A nonspecific term denoting degeneration of the retinal pigment epithelium and/or retinal photoreceptor cells.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000546</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Retinal degeneration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000553 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000553">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012374"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the uvea, the vascular layer of the eyeball.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000553</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the uvea</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000554 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000554">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000553"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0100533"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Inflammation of one or all portions of the uveal tract.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000554</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Uveitis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000556 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000556">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000479"/>
<obo:IAO_0000115>Retinal dystrophy is an abnormality of the retina associated with a hereditary process. Retinal dystrophies are defined by their predominantly monogenic inheritance and they are frequently associated with loss or dysfunction of photoreceptor cells as a primary or secondary event.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000556</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Retinal dystrophy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000572 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000572">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000504"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Loss of visual acuity (implying that vision was better at a certain timepoint in life - otherwise the term reduced visual acuity should be used (or a subclass of that).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000572</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Visual loss</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000587 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000587">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001098"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the optic nerve.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000587</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the optic nerve</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000598 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000598">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the ear.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000598</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the ear</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000608 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000608">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000546"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001103"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A nonspecific term denoting degeneration of the retinal pigment epithelium and/or retinal photoreceptor cells of the macula lutea.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000608</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Macular degeneration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000610 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000610">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000553"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001098"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any structural abnormality of the choroid.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000610</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal choroid morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000622 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000622">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000504"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Lack of sharpness of vision resulting in the inability to see fine detail.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000622</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Blurred vision</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000648 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000648">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012795"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Atrophy of the optic nerve. Optic atrophy results from the death of the retinal ganglion cell axons that comprise the optic nerve and manifesting as a pale optic nerve on fundoscopy.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000648</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Optic atrophy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000668 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000668">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0009804"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A developmental anomaly characterized by a reduced number of teeth, whereby up to 6 teeth are missing.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000668</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hypodontia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000707 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000707">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the nervous system.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000707</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the nervous system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000708 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000708">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012638"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of mental functioning including various affective, behavioural, cognitive and perceptual abnormalities.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000708</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Behavioral abnormality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000726 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000726">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001268"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A loss of global cognitive ability of sufficient amount to interfere with normal social or occupational function. Dementia represents a loss of previously present cognitive abilities, generally in adults, and can affect memory, thinking, language, judgment, and behavior.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000726</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Dementia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000741 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000741">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000745"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000741</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Apathy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000745 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000745">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0100851"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A reduction in goal-directed behavior, that is, motivation, the determinant of behavior and adaptation that allows individuals to get started, be energized to perform a sustained and directed action.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000745</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Diminished motivation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000750 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000750">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012758"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A degree of language development that is significantly below the norm for a child of a specified age.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000750</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Delayed speech and language development</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000759 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000759">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012639"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the peripheral nervous system, which is composed of the nerves that lead to or branch off from the central nervous system. This includes the cranial nerves (olfactory and optic nerves are technically part of the central nervous system).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000759</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal peripheral nervous system morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000765 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000765">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0009121"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any abnormality of the thorax (the region of the body formed by the sternum, the thoracic vertebrae and the ribs).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000765</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the thorax</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000766 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000766">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000765"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An anomaly of the sternum, also known as the breastbone.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000766</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the sternum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000768 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000768">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000766"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A deformity of the chest caused by overgrowth of the ribs and characterized by protrusion of the sternum.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000768</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pectus carinatum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000769 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000769">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the breast.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000769</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the breast</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000774 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000774">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0005257"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reduced width of the chest from side to side, associated with a reduced distance from the sternal notch to the tip of the shoulder.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000774</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Narrow chest</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000777 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000777">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000818"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0100763"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the thymus, an organ located in the upper anterior portion of the chest cavity just behind the sternum and whose main function is to provide an environment for T lymphocyte maturation.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000777</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the thymus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000811 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000811">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012243"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000811</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal external genitalia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000818 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000818">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the endocrine system.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000818</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the endocrine system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000819 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000819">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000818"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011014"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A group of abnormalities characterized by hyperglycemia and glucose intolerance.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000819</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Diabetes mellitus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000820 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000820">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000818"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the thyroid gland.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000820</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the thyroid gland</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000828 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000828">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000818"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the parathyroid gland.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000828</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the parathyroid gland</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000843 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000843">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011767"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Excessive production of parathyroid hormone (PTH) by the parathyroid glands.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000843</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hyperparathyroidism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000853 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000853">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011772"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An enlargement of the thyroid gland.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000853</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Goiter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000924 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000924">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the skeletal system.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000924</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the skeletal system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000925 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000925">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0009121"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any abnormality of the vertebral column.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000925</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the vertebral column</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000926 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000926">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0003312"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A flattened vertebral body shape with reduced distance between the vertebral endplates.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000926</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Platyspondyly</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000927 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000927">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011843"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The bones of the skeleton undergo a series of characteristic changes in size, shape, and calcification from fetal life until puberty. An abnormality of this process can include delayed or accelerated skeletal maturation, or deviation of some, but not all bones from the expected patterns of maturation.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000927</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of skeletal maturation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000929 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000929">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000234"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0009121"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the skull, the bony framework of the head which is comprised of eight cranial and fourteen facial bones.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000929</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the skull</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000940 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000940">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011314"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the structure or form of the diaphysis, i.e., of the main or mid-section (shaft) of a long bone.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000940</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal diaphysis morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000944 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000944">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002813"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011314"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of one or more metaphysis, i.e., of the somewhat wider portion of a long bone that is adjacent to the epiphyseal growth plate and grows during childhood.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000944</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the metaphysis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000951 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000951">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001574"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the skin.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000951</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the skin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000962 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000962">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011368"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hyperkeratosis is thickening of the outer layer of the skin, the stratum corneum, which is composed of large, polyhedral, plate-like envelopes filled with keratin which are the dead cells that have migrated up from the stratum granulosum.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000962</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hyperkeratosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000964 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000964">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011123"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Eczema is a form of dermatitis. The term eczema is broadly applied to a range of persistent skin conditions and can be related to a number of underlying conditions. Manifestations of eczema can include dryness and recurring skin rashes with redness, skin edema, itching and dryness, crusting, flaking, blistering, cracking, oozing, or bleeding.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000964</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Eczema</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000969 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000969">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011032"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormal accumulation of fluid beneath the skin, or in one or more cavities of the body.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000969</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Edema</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000972 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000972">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0007556"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010765"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hyperkeratosis affecting the palm of the hand and the sole of the foot.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000972</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Palmoplantar hyperkeratosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000975 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000975">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0007550"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal excessive perspiration (sweating) despite the lack of appropriate stimuli like hot and humid weather.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000975</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hyperhidrosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000978 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000978">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001933"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An ecchymosis (bruise) refers to the skin discoloration caused by the escape of blood into the tissues from ruptured blood vessels. This term refers to an abnormally increased susceptibility to bruising. The corresponding phenotypic abnormality is generally elicited on medical history as a report of frequent ecchymoses or bruising without adequate trauma.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000978</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bruising susceptibility</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000992 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000992">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011354"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An increased sensitivity of the skin to light. Photosensitivity may result in a rash upon exposure to the sun (which is known as photodermatosis). Photosensitivity can be diagnosed by phototests in which light is shone on small areas of skin.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000992</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Cutaneous photosensitivity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0000999 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0000999">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0005406"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any manifestation of a skin disease associated with the production of pus.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0000999</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pyoderma</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011121"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the pigmentation of the skin.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001000</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of skin pigmentation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001010">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001000"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A reduction of skin color related to a decrease in melanin production and deposition.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001010</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hypopigmentation of the skin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001022 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001022">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0005599"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0007513"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormal reduction in the amount of pigmentation (reduced or absent) of skin, hair and eye (iris and retina).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001022</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Albinism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000964"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Seborrheic dermatitis is a form of eczema which is closely related to dandruff. It causes dry or greasy peeling of the scalp, eyebrows, and face, and sometimes trunk.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001051</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Seborrheic dermatitis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001072 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001072">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011121"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Laminar thickening of skin.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001072</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Thickened skin</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001098 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001098">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004329"/>
<obo:IAO_0000115>Any structural abnormality of the fundus of the eye.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001098</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal fundus morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001103 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001103">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000479"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A structural abnormality of the macula lutea, which is an oval-shaped highly pigmented yellow spot near the center of the retina.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001103</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal macular morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001155 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001155">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002817"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality affecting one or both hands.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001155</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the hand</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001159 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001159">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011297"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Webbing or fusion of the fingers or toes, involving soft parts only or including bone structure. Bony fusions are revered to as &quot;bony&quot; syndactyly if the fusion occurs in a radio-ulnar axis. Fusions of bones of the fingers or toes in a proximo-distal axis are refered to as &quot;symphalangism&quot;.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001159</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Syndactyly</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001197 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001197">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the fetus or the birth of the fetus, excluding structural abnormalities.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001197</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of prenatal development or birth</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001249 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001249">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012759"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Subnormal intellectual functioning which originates during the developmental period. Intellectual disability, previously referred to as mental retardation, has been defined as an IQ score below 70.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001249</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Intellectual disability</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001250 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001250">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012638"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Seizures are an intermittent abnormality of the central nervous system due to a sudden, excessive, disorderly discharge of cerebral neurons and characterized clinically by some combination of disturbance of sensation, loss of consciousness, impairment of psychic function, or convulsive movements. The term epilepsy is used to describe chronic, recurrent seizures.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001250</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Seizures</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001252 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001252">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0003808"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Muscular hypotonia is an abnormally low muscle tone (the amount of tension or resistance to movement in a muscle), often involving reduced muscle strength. Hypotonia is characterized by a diminished resistance to passive stretching.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001252</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Muscular hypotonia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001262 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001262">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002360"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004372"/>
<obo:IAO_0000115>A state of abnormally strong desire for sleep during the daytime.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001262</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Excessive daytime somnolence</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001268 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001268">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0100543"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Loss of previously present mental abilities, generally in adults.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001268</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mental deterioration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001273 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001273">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002500"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the corpus callosum.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001273</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the corpus callosum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001274 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001274">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0007370"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Absence of the corpus callosum as a result of the failure of the corpus callosum to develop, which can be the result of a failure in any one of the multiple steps of callosal development including cellular proliferation and migration, axonal growth or glial patterning at the midline.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001274</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Agenesis of corpus callosum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001276 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001276">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002493"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0003808"/>
<obo:IAO_0000115>A condition in which there is increased muscle tone so that arms or legs, for example, are stiff and difficult to move.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001276</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hypertonia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001322 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001322">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012443"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001322</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Brain very small</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001336 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001336">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004305"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Very brief, involuntary random muscular contractions occurring at rest, in response to sensory stimuli, or accompanying voluntary movements.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001336</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Myoclonus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001363 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001363">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002648"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011329"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Craniosynostosis refers to the premature closure of the cranial sutures. Primary craniosynostosis refers to the closure of one or more sutures due to abnormalities in skull development, and secondary craniosynostosis results from failure of brain growth.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001363</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Craniosynostosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001367 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001367">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011842"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormal structure or form of the joints, i.e., one or more of the articulations where two bones join.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001367</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal joint morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001369 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001369">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001367"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Inflammation of a joint.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001369</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Arthritis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001373 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001373">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001367"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Displacement or malalignment of joints.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001373</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Joint dislocation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001392 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001392">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002012"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the liver.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001392</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the liver</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001394 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001394">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0410042"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A chronic disorder of the liver in which liver tissue becomes scarred and is partially replaced by regenerative nodules and fibrotic tissue resulting in loss of liver function.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001394</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Cirrhosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001396 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001396">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004297"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Impairment of bile flow due to obstruction in bile ducts.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001396</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Cholestasis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001480 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001480">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001000"/>
<obo:IAO_0000115>The presence of an increased number of freckles, small circular spots on the skin that are darker than the surrounding skin because of deposits of melanin.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001480</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Freckling</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001482 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001482">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0200036"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Slightly elevated lesions on or in the skin with a diameter of over 5 mm.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001482</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Subcutaneous nodule</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001507 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001507">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001507</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Growth abnormality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001510 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001510">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001507"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A deficiency or slowing down of growth pre- and postnatally.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001510</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Growth delay</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001513 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001513">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004324"/>
<obo:IAO_0000115>Accumulation of substantial excess body fat.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001513</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Obesity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001548 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001548">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000098"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Excessive postnatal growth which may comprise increased weight, increased length, and/or increased head circumference.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001548</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Overgrowth</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001574 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001574">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the integument, which consists of the skin and the superficial fascia.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001574</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the integument</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001581 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001581">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011123"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Infections of the skin that happen multiple times.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001581</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Recurrent skin infections</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001595 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001595">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011138"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the hair.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001595</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the hair</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001596 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001596">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011362"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Loss of hair from the head or body.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001596</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Alopecia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001597 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001597">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011138"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the nail.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001597</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the nail</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001626 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001626">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any abnormality of the cardiovascular system.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001626</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the cardiovascular system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001627 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001627">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0030680"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any structural anomaly of the heart.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001627</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal heart morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001650 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001650">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0031652"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The presence of a stenosis (narrowing) of the aortic valve.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001650</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Aortic valve stenosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001664 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001664">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004308"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A type of ventricular tachycardia characterized by polymorphioc QRS complexes that change in amplitue and cycle length, and thus have the appearance of oscillating around the baseline in the EKG.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001664</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Torsade de pointes</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001697 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001697">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001627"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the pericardium, i.e., of the fluid filled sac that surrounds the heart and the proximal ends of the aorta, vena cava, and the pulmonary artery.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001697</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal pericardium morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001718 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001718">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0031481"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Ab abnormal narrowing of the orifice of the mitral valve.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001718</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mitral stenosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001760 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001760">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002814"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the skeleton of foot.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001760</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the foot</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001762 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001762">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001883"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Talipes equinovarus (also called clubfoot) typically has four main components: inversion and adduction of the forefoot; inversion of the heel and hindfoot; equinus (limitation of extension) of the ankle and subtalar joint; and internal rotation of the leg.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001762</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Talipes equinovarus</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001789 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001789">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000969"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001197"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The abnormal accumulation of fluid in two or more fetal compartments, including ascites, pleural effusion, pericardial effusion, and skin edema.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001789</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hydrops fetalis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001871 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001871">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the hematopoietic system.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001871</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of blood and blood-forming tissues</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001872 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001872">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001871"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of platelets.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001872</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal thrombocyte morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001879 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001879">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001911"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An eosinophil abnormality.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001879</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of eosinophils</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001880 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001880">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001879"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001974"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Increased count of eosinophils in the blood.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001880</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Eosinophilia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001881 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001881">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001871"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010987"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of leukocytes.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001881</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal leukocyte morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001883 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001883">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0005656"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A deformity of foot and ankle that has different subtypes that are talipes equinovarus, talipes equinovalgus, talipes calcaneovarus and talipes calcaneovalgus.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001883</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Talipes</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001892 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001892">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001871"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormal susceptibility to bleeding, often referred to as a bleeding diathesis. A bleeding diathesis may be related to vascular, platelet and coagulation defects.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001892</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal bleeding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001894 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001894">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011873"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Increased numbers of platelets in the peripheral blood.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001894</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Thrombocytosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001911 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001911">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010974"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of granulocytes.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001911</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of granulocytes</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001913 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001913">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001911"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormally reduced number of granulocytes in the blood.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001913</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Granulocytopenia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001928 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001928">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001871"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the process of blood coagulation. That is, altered ability or inability of the blood to clot.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001928</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of coagulation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001933 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001933">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001892"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011276"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">This term refers to an abnormally increased susceptibility to bruising (purpura, petechiae, or ecchymoses).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001933</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Subcutaneous hemorrhage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001939 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001939">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001939</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of metabolism/homeostasis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001941 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001941">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004360"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal acid accumulation or depletion of base.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001941</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Acidosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001942 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001942">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001941"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Acid accumulation or depletion of base in the body due to buildup of metabolic acids.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001942</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Metabolic acidosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001943 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001943">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011015"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A decreased concentration of glucose in the blood.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001943</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hypoglycemia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001962 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001962">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011675"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A sensation that the heart is pounding or racing, which is a non-specific sign but may be a manifestation of arrhythmia.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001962</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Palpitations</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001965 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001965">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000234"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any anomaly of the scalp, the skin an subcutaneous tissue of the head on which head hair grows.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001965</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the scalp</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001966 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001966">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000095"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the mesangium, i.e., of the central part of the renal glomerulus between capillaries.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001966</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mesangial abnormality</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001967 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001967">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001966"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Diffuse sclerosis of the mesangium, as manifestated by diffuse mesangial matrix expansion.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001967</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Diffuse mesangial sclerosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001974 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001974">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011893"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormal increase in the number of leukocytes in the blood.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001974</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Leukocytosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001977 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001977">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001871"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Venous or arterial thrombosis (formation of blood clots) of spontaneous nature and which cannot be fully explained by acquired risk (e.g. atherosclerosis).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001977</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal thrombosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001997 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001997">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001369"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002149"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Recurrent attacks of acute inflammatory arthritis of a joint or set of joints caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001997</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Gout</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0001999 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0001999">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000271"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormal morphology (form) of the face or its components.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0001999</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal facial shape</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012639"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A structural abnormality of the central nervous system.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002011</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Morphological abnormality of the central nervous system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002012">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0025031"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the viscera of the abdomen.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002012</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the abdominal organs</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002024">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002242"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Impaired ability to absorb one or more nutrients from the intestine.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002024</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Malabsorption</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002060 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002060">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0100547"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the telencephalon, which is also known as the cerebrum.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002060</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the cerebrum</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002063 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002063">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011442"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Continuous involuntary sustained muscle contraction. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from muscle spasticity.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002063</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Rigidity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002069 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002069">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002197"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Generalized tonic-clonic seizures are generalized seizures with bilateral symmetrical tonic contraction then bilateral clonic contractions of somatic muscles usually associated with autonomic phenomena.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002069</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Generalized tonic-clonic seizures</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002086 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002086">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the respiratory system, which include the airways, lungs, and the respiratory muscles.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002086</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the respiratory system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002088 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002088">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012252"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Any structural anomaly of the lung.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002088</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal lung morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002093 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002093">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002795"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002093</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Respiratory insufficiency</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002094 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002094">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002795"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Difficult or labored breathing.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002094</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Dyspnea</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002098 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002098">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002094"/>
<obo:IAO_0000115>Difficulty in breathing. The physical presentation of respiratory distress is generally referred to as labored breathing, while the sensation of respiratory distress is called shortness of breath or dyspnea.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002098</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Respiratory distress</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002099 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002099">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002795"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0100326"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Asthma is characterized by increased responsiveness of the tracheobronchial tree to multiple stimuli, leading to narrowing of the air passages with resultant dyspnea, cough, and wheezing.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002099</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Asthma</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002102 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002102">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002103"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Inflammation of the pleura.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002102</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pleuritis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002103 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002103">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002088"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the pulmonary pleura, the thin, transparent membrane which covers the lungs and lines the inside of the chest walls.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002103</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the pleura</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002113 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002113">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002088"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002113</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pulmonary infiltrates</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002121 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002121">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002197"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011146"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Recurrent absence seizures are generalized seizures and are characterized by a loss of consciousness, thus, are a form of dialeptic seizures.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002121</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Absence seizures</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002143 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002143">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002011"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the spinal cord (myelon).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002143</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the spinal cord</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002149 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002149">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002157"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004368"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormally high level of uric acid in the blood.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002149</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hyperuricemia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002156 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002156">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0003355"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010919"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An increased concentration of homocystine in the urine.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002156</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Homocystinuria</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002157 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002157">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0004364"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An increased concentration of nitrogen compounds in the blood.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002157</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Azotemia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002164 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002164">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001597"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The presence of developmental dysplasia of the nail.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002164</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Nail dysplasia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002197 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002197">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001250"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Seizures of with initial involvement of both cerebral hemispheres.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002197</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Generalized seizures</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002209 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002209">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0008070"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0100037"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Decreased number of head hairs per unit area.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002209</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sparse scalp hair</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002239 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002239">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011029"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012719"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hemorrhage affecting the gastrointestinal tract.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002239</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Gastrointestinal hemorrhage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002242 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002242">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012718"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the intestine. The closely related term enteropathy is used to refer to any disease of the intestine.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002242</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal intestine morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002257 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002257">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012384"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Chronic inflammation of the nasal mucosa.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002257</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Chronic rhinitis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002344 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002344">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001268"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002344</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Progressive neurologic deterioration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002360 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002360">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000708"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of sleep including such phenomena as 1) insomnia/hypersomnia, 2) non-restorative sleep, 3) sleep schedule disorder, 4) excessive daytime somnolence, 5) sleep apnea, and 6) restlessness.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002360</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sleep disturbance</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002493 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002493">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011442"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A functional anomaly of the upper motor neuron. The upper motor neurons are neurons of the primary motor cortex which project to the brainstem and spinal chord via the corticonuclear, corticobulbar and corticospinal (pyramidal) tracts. They are involved in control of voluntary movements.
Dysfunction leads to weakness, impairment of fine motor movements, spasticity, hyperreflexia and abnormal pyramidal signs.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002493</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Upper motor neuron dysfunction</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002500 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002500">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010993"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the cerebral white matter.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002500</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the cerebral white matter</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002503 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002503">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0003133"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002503</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Spinocerebellar tract degeneration</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002584 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002584">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002239"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002242"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bleeding from the intestines.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002584</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Intestinal bleeding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002597 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002597">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0001626"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the vasculature.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002597</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the vasculature</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002607 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002607">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012700"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0031064"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Involuntary fecal soiling in adults and children who have usually already been toilet trained.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002607</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bowel incontinence</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002617 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002617">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0025015"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormal outpouching or sac-like dilatation in the wall of an atery, vein or the heart.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002617</oboInOwl:id>
<rdfs:label>Dilatation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002648 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002648">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002683"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The presence of an abnormal shape of the calvaria (skullcap), that is, of that part of the skull that is made up of the superior portions of the frontal bone, occipital bone, and parietal bones and covers the cranial cavity that contains the brain.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002648</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of calvarial morphology</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002650 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002650">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010674"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The presence of an abnormal lateral curvature of the spine.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002650</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Scoliosis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002651 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002651">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002652"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002651</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Spondyloepimetaphyseal dysplasia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002652 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002652">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011842"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A general term describing features characterized by abnormal development of bones and connective tissues.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002652</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Skeletal dysplasia</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002653 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002653">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011843"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0012531"/>
<obo:IAO_0000115>An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to bone.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002653</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bone pain</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002664 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002664">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumour).</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002664</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Neoplasm</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002683 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002683">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000929"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the calvaria, which is the roof of the skull formed by the frontal bone, parietal bones, and occipital bone.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002683</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the calvaria</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002715 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002715">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000118"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An abnormality of the immune system.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002715</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Abnormality of the immune system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002718 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002718">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002719"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Increased susceptibility to bacterial infections, as manifested by recurrent episodes of bacterial infection.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002718</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Recurrent bacterial infections</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002719 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002719">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010978"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Increased susceptibility to infections.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002719</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Recurrent infections</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002721 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002721">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0010978"/>
<obo:IAO_0000115>Failure of the immune system to protect the body adequately from infection, due to the absence or insufficiency of some component process or substance.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002721</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Immunodeficiency</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002750 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002750">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0000927"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A decreased rate of skeletal maturation. Delayed skeletal maturation can be diagnosed on the basis of an estimation of the bone age from radiographs of specific bones in the human body.</obo:IAO_0000115>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002750</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Delayed skeletal maturation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/HP_0002795 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/HP_0002795">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002086"/>
<oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HP:0002795</oboInOwl:id>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Functional respiratory abnormality</rdfs:label>
</owl:Class>