diff --git a/lighthouse-extension/app/manifest.json b/lighthouse-extension/app/manifest.json
index 3d0a0e680a1a..83c213c4b8e6 100644
--- a/lighthouse-extension/app/manifest.json
+++ b/lighthouse-extension/app/manifest.json
@@ -19,6 +19,7 @@
   "permissions": [
     "activeTab",
     "debugger",
+    "management",
     "storage"
   ],
   "browser_action": {
diff --git a/lighthouse-extension/app/src/lighthouse-background.js b/lighthouse-extension/app/src/lighthouse-background.js
index d747d23cb44a..7f2ad4c29711 100644
--- a/lighthouse-extension/app/src/lighthouse-background.js
+++ b/lighthouse-extension/app/src/lighthouse-background.js
@@ -26,11 +26,36 @@ const log = require('../../../lighthouse-core/lib/log');
 const ReportGenerator = require('../../../lighthouse-core/report/report-generator');
 
 const STORAGE_KEY = 'lighthouse_audits';
-const _flatten = arr => [].concat(...arr);
 
+let installedExtensions = [];
 let lighthouseIsRunning = false;
 let latestStatusLog = [];
 
+const _flatten = arr => [].concat(...arr);
+
+/**
+ * Enables or disables all other installed chrome extensions. The initial list
+ * of the user's extension is created when the background page is started.
+ * @param {!boolean} enable If true, enables all other installed extensions.
+ *     False disables them.
+ * @param {!Promise}
+ */
+function enableOtherChromeExtensions(enable) {
+  const str = enable ? 'enabling' : 'disabling';
+  log.log('Chrome', `${str} ${installedExtensions.length} extensions.`);
+
+  return Promise.all(installedExtensions.map(info => {
+    return new Promise((resolve, reject) => {
+      chrome.management.setEnabled(info.id, enable, _ => {
+        if (chrome.runtime.lastError) {
+          reject(chrome.runtime.lastError);
+        }
+        resolve();
+      });
+    });
+  }));
+}
+
 /**
  * Filter out any unrequested aggregations from the config. If any audits are
  * no longer needed by any remaining aggregations, filter out those as well.
@@ -124,8 +149,7 @@ window.runLighthouseForConnection = function(connection, url, options, requested
   lighthouseIsRunning = true;
   updateBadgeUI(url);
 
-  // Run Lighthouse.
-  return Runner.run(connection, runOptions)
+  return Runner.run(connection, runOptions) // Run Lighthouse.
     .then(result => {
       lighthouseIsRunning = false;
       updateBadgeUI();
@@ -148,11 +172,18 @@ window.runLighthouseInExtension = function(options, requestedAggregations) {
   // Default to 'info' logging level.
   log.setLevel('info');
   const connection = new ExtensionProtocol();
-  return connection.getCurrentTabURL()
+  return enableOtherChromeExtensions(false)
+    .then(_ => connection.getCurrentTabURL())
     .then(url => window.runLighthouseForConnection(connection, url, options, requestedAggregations))
     .then(results => {
-      const blobURL = window.createReportPageAsBlob(results, 'extension');
-      chrome.tabs.create({url: blobURL});
+      return enableOtherChromeExtensions(true).then(_ => {
+        const blobURL = window.createReportPageAsBlob(results, 'extension');
+        chrome.tabs.create({url: blobURL});
+      });
+    }).catch(err => {
+      return enableOtherChromeExtensions(true).then(_ => {
+        throw err;
+      });
     });
 };
 
@@ -277,7 +308,19 @@ window.isRunning = function() {
   return lighthouseIsRunning;
 };
 
+// Run when in extension context, but not in devtools.
 if (window.chrome && chrome.runtime) {
+  // Get list of installed extensions that are enabled and can be disabled.
+  // Extensions are not allowed to be disabled if they are under an admin policy.
+  chrome.management.getAll(installs => {
+    chrome.management.getSelf(lighthouseCrxInfo => {
+      installedExtensions = installs.filter(info => {
+        return info.id !== lighthouseCrxInfo.id && info.type === 'extension' &&
+               info.enabled && info.mayDisable;
+      });
+    });
+  });
+
   chrome.runtime.onInstalled.addListener(details => {
     if (details.previousVersion) {
       // eslint-disable-next-line no-console