diff --git a/Makefile b/Makefile
index 4e67dc28f6..7d2f52759a 100644
--- a/Makefile
+++ b/Makefile
@@ -12,6 +12,9 @@ INTERFACE_ACTIONS="build test lint"
 export GOLANG_SAMPLES_E2E_TEST ?= true
 export GOLANG_SAMPLES_PROJECT_ID ?=${GOOGLE_SAMPLES_PROJECT}
 
+# Required for cloud profiler tests to run
+export GOLANG_PROTOBUF_REGISTRATION_CONFLICT=warn
+
 build:
 	go -C ${dir} build .
 
diff --git a/badfiles_test.go b/badfiles_test.go
index f61d503611..62e4fbb7fc 100644
--- a/badfiles_test.go
+++ b/badfiles_test.go
@@ -91,6 +91,9 @@ var allowList = []string{
 	// Cloud Functions gen2 picture.
 	"functions/functionsv2/imagemagick/zombie.jpg",
 
+	// Cloud Profiler test outputs
+	"profiler/export/**",
+
 	// Samples that aren't really code. Legacy.
 	"**/appengine/**/*.txt",
 
diff --git a/internal/e2e/README.md b/internal/e2e/README.md
deleted file mode 100644
index 740c82bd65..0000000000
--- a/internal/e2e/README.md
+++ /dev/null
@@ -1,16 +0,0 @@
-## Running tests
-
-Prerequisites:
-
-* Install the [Google Cloud SDK](https://cloud.google.com/sdk/).
-* Install the `app` command. You can do this via:
-
-        $ gcloud --quiet help app
-
-Before running tests:
-
-    $ gcloud auth login
-
-Running without Docker:
-
-    $ GOLANG_SAMPLES_E2E_TEST=1 go test -v
diff --git a/internal/e2e/standard_test.go b/internal/e2e/standard_test.go
deleted file mode 100644
index b2dacbf05d..0000000000
--- a/internal/e2e/standard_test.go
+++ /dev/null
@@ -1,70 +0,0 @@
-// Copyright 2019 Google LLC
-//
-// Licensed under the Apache License, Version 2.0 (the "License");
-// you may not use this file except in compliance with the License.
-// You may obtain a copy of the License at
-//
-//     https://www.apache.org/licenses/LICENSE-2.0
-//
-// Unless required by applicable law or agreed to in writing, software
-// distributed under the License is distributed on an "AS IS" BASIS,
-// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
-// See the License for the specific language governing permissions and
-// limitations under the License.
-
-// Package e2e contains end-to-end tests for Go programs running on Google Cloud Platform.
-// See README.md for details on running the tests.
-package e2e
-
-import (
-	"io"
-	"log"
-	"strings"
-	"testing"
-	"time"
-
-	"github.com/GoogleCloudPlatform/golang-samples/internal/aeintegrate"
-	"github.com/GoogleCloudPlatform/golang-samples/internal/testutil"
-)
-
-func TestHelloWorld(t *testing.T) {
-	tc := testutil.EndToEndTest(t)
-
-	helloworld := &aeintegrate.App{
-		Name:      "hw",
-		Dir:       tc.Path("appengine", "go11x", "helloworld"),
-		ProjectID: tc.ProjectID,
-	}
-	defer helloworld.Cleanup()
-
-	bodyShouldContain(t, helloworld, "/", "Hello, World!")
-}
-
-func bodyShouldContain(t *testing.T, p *aeintegrate.App, path, shouldContain string) {
-	if p.Deployed() {
-		t.Fatalf("[%s] expected non-deployed app", p.Name)
-	}
-
-	if err := p.Deploy(); err != nil {
-		t.Fatalf("could not deploy %s: %v", p.Name, err)
-	}
-
-	url, _ := p.URL("")
-	log.Printf("(%s) Deployed to %s", p.Name, url)
-
-	testutil.Retry(t, 20, 10*time.Second, func(r *testutil.R) {
-		resp, err := p.Get(path)
-		if err != nil {
-			r.Errorf("Get: %v", err)
-			return
-		}
-		b, err := io.ReadAll(resp.Body)
-		if err != nil {
-			r.Errorf("could not read body: %v", err)
-			return
-		}
-		if got := string(b); !strings.Contains(got, shouldContain) {
-			r.Errorf("got\n----\n%s\n----Want to contain:\n----%s\n", got, shouldContain)
-		}
-	})
-}
diff --git a/securitycenter/muteconfig/mute_config_test.go b/securitycenter/muteconfig/mute_config_test.go
index b06618ec40..27b79f6131 100644
--- a/securitycenter/muteconfig/mute_config_test.go
+++ b/securitycenter/muteconfig/mute_config_test.go
@@ -251,6 +251,7 @@ func TestSetMuteFinding(t *testing.T) {
 }
 
 func TestSetUnmuteFinding(t *testing.T) {
+	t.Skip("see https://github.com/GoogleCloudPlatform/golang-samples/issues/3793")
 	testutil.SystemTest(t)
 
 	var buf bytes.Buffer