diff --git a/compute/encryption/requirements.txt b/compute/encryption/requirements.txt
index ca64bbbc0f4..85aa34a6acf 100644
--- a/compute/encryption/requirements.txt
+++ b/compute/encryption/requirements.txt
@@ -1,4 +1,4 @@
-cryptography==45.0.1
+cryptography==46.0.1
 requests==2.32.4
 google-api-python-client==2.131.0
 google-auth==2.38.0
diff --git a/iap/requirements.txt b/iap/requirements.txt
index 3c2961ba6a2..cf8c69ce70b 100644
--- a/iap/requirements.txt
+++ b/iap/requirements.txt
@@ -1,4 +1,4 @@
-cryptography==45.0.1
+cryptography==46.0.1
 Flask==3.0.3
 google-auth==2.38.0
 gunicorn==23.0.0
diff --git a/kms/attestations/requirements.txt b/kms/attestations/requirements.txt
index 21fdd0e1147..57f2d85282d 100644
--- a/kms/attestations/requirements.txt
+++ b/kms/attestations/requirements.txt
@@ -1,4 +1,4 @@
-cryptography==45.0.1
+cryptography==46.0.1
 pem==21.2.0; python_version < '3.8'
 pem==23.1.0; python_version > '3.7'
 requests==2.31.0
diff --git a/kms/snippets/requirements.txt b/kms/snippets/requirements.txt
index 6e15391cfd6..c194390ba9b 100644
--- a/kms/snippets/requirements.txt
+++ b/kms/snippets/requirements.txt
@@ -1,4 +1,4 @@
 google-cloud-kms==3.2.1
-cryptography==45.0.1
+cryptography==46.0.1
 crcmod==1.7
 jwcrypto==1.5.6
\ No newline at end of file
diff --git a/media_cdn/requirements.txt b/media_cdn/requirements.txt
index 46e87e778f4..bb78c80108b 100644
--- a/media_cdn/requirements.txt
+++ b/media_cdn/requirements.txt
@@ -1,2 +1,2 @@
 six==1.16.0
-cryptography==45.0.1
+cryptography==46.0.1
diff --git a/privateca/snippets/requirements-test.txt b/privateca/snippets/requirements-test.txt
index bfeffa644e9..3a52fc0a739 100644
--- a/privateca/snippets/requirements-test.txt
+++ b/privateca/snippets/requirements-test.txt
@@ -1,4 +1,4 @@
 pytest==8.2.0
 google-auth==2.38.0
-cryptography==45.0.1
+cryptography==46.0.1
 backoff==2.2.1
\ No newline at end of file