iviNSCLC is an R package that runs the Innovation and Value Initiative's (IVI's) non-small cell lung cancer (NSCLC) simulation model (the IVI-NSCLC model). The model simulates the costs, health outcomes, and risks associated with sequences of treatment including EGFR Tyrosine Kinase Inhibitors (TKIs), platinum-based doublet chemotherapy (PBDC), anti–vascular endothelial growth factor (anti-VEGF) therapy, and immune checkpoint inhibitors for patients with epidermal growth factor receptor (EGFR) positive NSCLC.
# Install the development version from GitHub: # install.packages("devtools") devtools::install_github("InnovationValueInitiative/IVI-NSCLC")
The components of the package
iviNSCLC are distributed in eight directories:
R: contains all R related code for simulating disease progression, costs, and QALYs. The code relies heavily on the
Rscripts to generate tables used in the package which are saved into
data. The input used in the NMA are included in the subdrectory
mstate-nma-data. The output of the NMA is stored in the subdirectory
data: Contains tables created by the
data-raw. These are the parameter estimates that load with the package and can be viewed with
data(package = "iviNSCLC").
docs: Articles, references, and author information are stored here.
man: Manual and general documentation.
pkgdown: The package website.
tests: Unit tests for the package.
vignettes: Files for the package tutorial.