diff --git a/sdc/__init__.py b/sdc/__init__.py
index 3f2183345..5647ebd7d 100644
--- a/sdc/__init__.py
+++ b/sdc/__init__.py
@@ -62,6 +62,7 @@
     # sdc.datatypes.hpat_pandas_dataframe_pass.sdc_nopython_pipeline_lite_register
 
     import sdc.rewrites.dataframe_constructor
+    import sdc.rewrites.dataframe_getitem_attribute
     import sdc.datatypes.hpat_pandas_functions
     import sdc.datatypes.hpat_pandas_dataframe_functions
 else:
diff --git a/sdc/rewrites/dataframe_getitem_attribute.py b/sdc/rewrites/dataframe_getitem_attribute.py
new file mode 100644
index 000000000..e0e102839
--- /dev/null
+++ b/sdc/rewrites/dataframe_getitem_attribute.py
@@ -0,0 +1,97 @@
+# *****************************************************************************
+# Copyright (c) 2020, Intel Corporation All rights reserved.
+#
+# Redistribution and use in source and binary forms, with or without
+# modification, are permitted provided that the following conditions are met:
+#
+#     Redistributions of source code must retain the above copyright notice,
+#     this list of conditions and the following disclaimer.
+#
+#     Redistributions in binary form must reproduce the above copyright notice,
+#     this list of conditions and the following disclaimer in the documentation
+#     and/or other materials provided with the distribution.
+#
+# THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
+# AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO,
+# THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR
+# PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR
+# CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL,
+# EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO,
+# PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS;
+# OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY,
+# WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR
+# OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE,
+# EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+# *****************************************************************************
+
+from numba.ir import Assign, Const, Expr, Var
+from numba.ir_utils import mk_unique_var
+from numba.rewrites import register_rewrite, Rewrite
+from numba.types import StringLiteral
+from numba.typing import signature
+
+from sdc.config import config_pipeline_hpat_default
+from sdc.hiframes.pd_dataframe_type import DataFrameType
+
+
+if not config_pipeline_hpat_default:
+    @register_rewrite('after-inference')
+    class RewriteDataFrameGetItemAttr(Rewrite):
+        """
+        Search for calls of df.attr and replace it with calls of df['attr']:
+        $0.2 = getattr(value=df, attr=A) -> $const0.0 = const(str, A)
+                                            $0.2 = static_getitem(value=df, index=A, index_var=$const0.0)
+        """
+
+        def match(self, func_ir, block, typemap, calltypes):
+            self.func_ir = func_ir
+            self.block = block
+            self.typemap = typemap
+            self.calltypes = calltypes
+            self.getattrs = getattrs = set()
+            for expr in block.find_exprs(op='getattr'):
+                obj = typemap[expr.value.name]
+                if not isinstance(obj, DataFrameType):
+                    continue
+                if expr.attr in obj.columns:
+                    getattrs.add(expr)
+
+            return len(getattrs) > 0
+
+        def apply(self):
+            new_block = self.block.copy()
+            new_block.clear()
+            for inst in self.block.body:
+                if isinstance(inst, Assign) and inst.value in self.getattrs:
+                    const_assign = self._assign_const(inst)
+                    new_block.append(const_assign)
+
+                    inst = self._assign_getitem(inst, index=const_assign.target)
+
+                new_block.append(inst)
+
+            return new_block
+
+        def _assign_const(self, inst, prefix='$const0'):
+            """Create constant from attribute of the instruction."""
+            const_node = Const(inst.value.attr, inst.loc)
+            const_var = Var(inst.target.scope, mk_unique_var(prefix), inst.loc)
+
+            self.func_ir._definitions[const_var.name] = [const_node]
+            self.typemap[const_var.name] = StringLiteral(inst.value.attr)
+
+            return Assign(const_node, const_var, inst.loc)
+
+        def _assign_getitem(self, inst, index):
+            """Create getitem instruction from the getattr instruction."""
+            new_expr = Expr.getitem(inst.value.value, index, inst.loc)
+            new_inst = Assign(value=new_expr, target=inst.target, loc=inst.loc)
+
+            self.func_ir._definitions[inst.target] = [new_expr]
+            self.calltypes[new_expr] = signature(
+                self.typemap[inst.target.name],
+                self.typemap[new_expr.value.name],
+                self.typemap[new_expr.index.name]
+            )
+
+            return new_inst
diff --git a/sdc/tests/test_dataframe.py b/sdc/tests/test_dataframe.py
index a28eacf7b..63599df5a 100644
--- a/sdc/tests/test_dataframe.py
+++ b/sdc/tests/test_dataframe.py
@@ -1367,6 +1367,15 @@ def test_impl(df):
 
         pd.testing.assert_series_equal(sdc_func(df), test_impl(df))
 
+    def test_df_getitem_attr(self):
+        def test_impl(df):
+            return df.A
+
+        sdc_func = self.jit(test_impl)
+        df = gen_df(test_global_input_data_float64)
+
+        pd.testing.assert_series_equal(sdc_func(df), test_impl(df))
+
     @skip_numba_jit
     def test_isin_df1(self):
         def test_impl(df, df2):