using Plots
plt = plot([0,10], yflip=true)
plot!([1,2], [0,4], arrow=true)
draws a line at the right location and an additional line with arrow, placed as if the axis is not flipped.
I think it's a bug in GR, but haven't been able to figure out how to directly call GR.polyline and GR.drawarrow and view the results.