A new code base for the IME project.
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Ath_IME_k5_400_400_complete.params
Athaliana_IME_errors.txt
Athaliana_IME_exon.fa
Athaliana_IME_five_prime_UTR.fa
Athaliana_IME_intron.fa
Athaliana_IME_three_prime_UTR.fa
README.md
README_IMEter_v2.1.md
README_IMEter_v2.2.md
README_observations.md
db_IME_Rose_WT_introns.fa
ditrainer.pl
expression.txt
final_IME_scores_Rose_WT.tsv
ime_distance_info.pl
ime_explore_parameter_space.pl
ime_trainer.pl
imeter.pl
mean.pl
proc_phytozome.pl

README.md

Updates and improvements to the IMEter software

The IMEter is a tool that can help predict the effects of Intron-Mediated Enhancement (IME) on gene expression. After training from suitable input data, the IMEter can be used to score any desired intron sequence (with highers scores indicating a higher potential for enhancement).

Two papers have been published that describe the first two versions of the IMEter:

This GitHub repository will track development on the latest — as yet unpublished — version of the IMEter (v2.1) as well as the intitial work on the next generation of the software (IMEter v2.2). Please see the following two READMEs for more details: