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This is the software for cryo-EM map processing and resolution estimation using FDR-FSC from the publication "Permutation testing of Fourier shell correlation for resolution estimation of cryo-EM maps" by Beckers et al., (2020) in Journal of Structural Biology

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MaximilianBeckers/SPOC

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SPOC - Statistical Processing of cryo-EM maps

SPOC, short for Statistical Processing of cryo-EM maps, is a software package which contains statistical tools for the analysis and processing of cryo-EM maps. Included are tools for Confidence Map generation, local map processing as well as resolution estimation (global and local) by permutation testing and false discovery rate control.

If you found SPoC useful for your work, please consider citing the following articles:

Beckers M., and Sachse C. (2020) Permutation testing of Fourier shell correlation for resolution estimation of cryo-EM maps. J Struct Biol 212, 107579

If you found the confidence maps useful, the following article is the main resource for reference:

Beckers, M., Jakobi, A. J., Sachse, C. (2019) Thresholding of cryo-EM density maps by false discovery rate control. IUCr Journal 6 (1)

For a detailed introduction, please see the file SPOC_tutorial.pdf

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This is the software for cryo-EM map processing and resolution estimation using FDR-FSC from the publication "Permutation testing of Fourier shell correlation for resolution estimation of cryo-EM maps" by Beckers et al., (2020) in Journal of Structural Biology

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