diff --git a/Utilities/Maintenance/AddEmptyDefaultMemberInitializers.cxx b/Utilities/Maintenance/AddEmptyDefaultMemberInitializers.cxx
new file mode 100644
index 00000000000..796d2f8fc68
--- /dev/null
+++ b/Utilities/Maintenance/AddEmptyDefaultMemberInitializers.cxx
@@ -0,0 +1,211 @@
+/*=========================================================================
+ *
+ *  Copyright NumFOCUS
+ *
+ *  Licensed under the Apache License, Version 2.0 (the "License");
+ *  you may not use this file except in compliance with the License.
+ *  You may obtain a copy of the License at
+ *
+ *         https://www.apache.org/licenses/LICENSE-2.0.txt
+ *
+ *  Unless required by applicable law or agreed to in writing, software
+ *  distributed under the License is distributed on an "AS IS" BASIS,
+ *  WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ *  See the License for the specific language governing permissions and
+ *  limitations under the License.
+ *
+ *=========================================================================*/
+
+// Script to add in-class {} member initializers to ITK classes that have one or more virtual member function,
+// itkNewMacro, itkSimpleNewMacro, or itkCreateAnotherMacro calls.
+//
+// Tested with Visual Studio 2019 (C++14).
+//
+// Needs to have the directory path to the ITK sources as command-line argument, for example:
+//
+//     AddEmptyDefaultMemberInitializers.exe D:\src\ITK\Modules
+//
+// Initial version by Niels Dekker, LKEB, Leiden University Medical Center, 2023
+
+#define _SILENCE_EXPERIMENTAL_FILESYSTEM_DEPRECATION_WARNING
+
+#include <cassert>
+#include <cctype>
+#include <cstring>
+#include <deque>
+#include <experimental/filesystem>
+#include <fstream>
+#include <iostream>
+#include <regex>
+#include <sstream>
+#include <string>
+
+using namespace std::experimental::filesystem::v1;
+
+namespace
+{
+using Lines = std::deque<std::string>;
+
+auto
+ReadFile(const path & filePath)
+{
+  Lines result;
+
+  std::ifstream inputFileStream{ filePath };
+  std::string   line;
+  while (std::getline(inputFileStream, line))
+  {
+    result.push_back(line);
+  }
+  return result;
+}
+
+void
+WriteFile(const path & filePath, const Lines & lines)
+{
+  std::ofstream outputFileStream{ filePath };
+  for (const auto & line : lines)
+  {
+    outputFileStream << line << '\n';
+  }
+}
+
+template <unsigned int VLength>
+bool
+StringStartsWith(const std::string & str, const char (&substr)[VLength])
+{
+  assert(substr[VLength - 1] == '\0');
+  return str.compare(0, VLength - 1, substr) == 0;
+}
+
+template <unsigned int VLength>
+bool
+StringEndsWith(const std::string & str, const char (&substr)[VLength])
+{
+  assert(substr[VLength - 1] == '\0');
+  return str.size() >= VLength && str.compare(str.size() + 1 - VLength, VLength - 1, substr) == 0;
+}
+
+unsigned int
+AddInitializers(Lines & lines)
+{
+  auto numberOfAddedInitializers = 0u;
+
+  bool virtualMemberFunctionEncountered{ false };
+
+  for (auto & line : lines)
+  {
+    const auto lineStartsWith = [&line](const auto & substr) { return StringStartsWith(line, substr); };
+    const auto lineEndsWith = [&line](const auto & substr) { return StringEndsWith(line, substr); };
+
+    const auto numberOfChars = line.size();
+
+    if (numberOfChars > 0)
+    {
+      if (lineStartsWith("  itkNewMacro(") || lineStartsWith("  itkSimpleNewMacro(") ||
+          lineStartsWith("  itkCreateAnotherMacro(") || lineStartsWith("  virtual ") || lineEndsWith(" override") ||
+          lineEndsWith(" override;") || lineEndsWith(" override = default;"))
+      {
+        virtualMemberFunctionEncountered = true;
+      }
+      else
+      {
+        if (virtualMemberFunctionEncountered)
+        {
+          if (lineStartsWith("};"))
+          {
+            // Class definition ended here.
+            virtualMemberFunctionEncountered = false;
+          }
+          else
+          {
+            if (line.back() == ';' && lineStartsWith("  ") && line.find(" static ") == std::string::npos &&
+                line.find(" std::unique_ptr") == std::string::npos &&
+                line.find(" itk::SmartPointer") == std::string::npos)
+            {
+              // The regular expression explicitly skips lines of code that have a `)` at the end, like:
+              // itkSetVectorMacro(NumberOfIterations, unsigned int, m_NumberOfLevels);
+              const std::regex expression{ R"(  \w.* m_\w[^{}=]*[^{}=\)];)" };
+
+              // Regular expression that matches a C++ reference (`&`).
+              const std::regex expressionReference{ R"(  \w.* & m_\w[^{}=]+;)" };
+
+              if (std::regex_match(line, expression) && !std::regex_match(line, expressionReference))
+              {
+                line.pop_back();
+                line.append("{};");
+                std::cout << line << '\n';
+                ++numberOfAddedInitializers;
+              }
+            }
+          }
+        }
+      }
+    }
+  }
+  return numberOfAddedInitializers;
+}
+
+auto
+ProcessFile(const path & filePath)
+{
+  auto       lines = ReadFile(filePath);
+  const auto numberOfAddedInitializers = AddInitializers(lines);
+  if (numberOfAddedInitializers > 0)
+  {
+    std::cout << "Added " << numberOfAddedInitializers << " initializer(s) to " << filePath.string() << std::endl;
+    WriteFile(filePath, lines);
+  }
+  return numberOfAddedInitializers;
+}
+
+void
+ProcessDirectory(const path & directoryPath)
+{
+  auto numberOfAddedInitializers = 0u;
+
+  for (const auto & entry : recursive_directory_iterator{ directoryPath })
+  {
+    const auto & path = entry.path();
+    const auto & extension = path.extension();
+
+    if ((!extension.empty()) && extension.string() == ".h" && StringStartsWith(path.stem().string(), "itk") &&
+        is_regular_file(path))
+    {
+      numberOfAddedInitializers += ProcessFile(path);
+    }
+  }
+  std::cout << "Added in total " << numberOfAddedInitializers << " initializer(s) to " << directoryPath.string()
+            << std::endl;
+}
+} // namespace
+
+
+int
+main(int argc, char ** argv)
+{
+  if (argc != 2)
+  {
+    std::cout << "Please specify the source directory path as command-line argument."
+                 "\nNote: This program will modify the source files in-place!!!"
+              << std::endl;
+  }
+  else
+  {
+    if (argv == nullptr)
+    {
+      return EXIT_FAILURE;
+    }
+    const char * const arg = argv[1];
+
+    if (arg == nullptr)
+    {
+      return EXIT_FAILURE;
+    }
+    ProcessDirectory(arg);
+  }
+
+  std::cout << "Press anything to continue" << std::endl;
+  std::cin.get();
+  return EXIT_SUCCESS;
+}