The National Cancer Institute’s (NCI) Comprehensive Data Resource (CDR) is a distributed web-based system that manages and maintains multi-dimensional data models on biospecimens. The CDR was developed and is currently utilized to collect biospecimen annotation and clinical data on biospecimens collected from cancer patient donors and post-mortem donors, for the NCI’s Biospecimen Pre-analytical Variables (BPV) and NIH Genotype-tissue Expression (GTEx) programs.
The CDR provides secure data access based on a user’s roles and privileges. Through dynamic content redaction, it protects private information in compliance with HIPAA regulations. Its graphic user interfaces streamline data entry workflow based on SOPs for sample collection and processing. The automated data checks and validations confirm data integrity and SOP adherence simultaneously.
More information can be found here:
The CDR-Lite is a Grails application. To get this standalone version up and running, please follow the steps below. Prerequisites:
Knowlege of Java and Git is assumed.
Install the latest JDK 7 per instructions for your environment. JDK 8 is not supported at this time.
Install PostgreSQL 9.3
Create a database called cdr. Create a user and password. By default, the cdrlite will try to connect to the database as “cdr/admin.” The cdr user will not need any special privileges. Through hibernate, it will create tables and sequences only. The database, user and password you create will need to be synchronized with DataSource.groovy which can be found in the conf folder under grails-app.
Install Grails 2.4.4 per instructions for your environment. Later versions of Grails are not supported at this time.
See here for more Grails installation information: http://grails.org/doc/latest/guide/gettingStarted.html
After cloning from GitHub, open a console window, navigate to the cdrlite folder and run the following commands:
set JAVA_OPTS=-XX:MaxPermSize=128m -XX:PermSize=512m -Xms1024m -Xmx2048m (This is a generous estimate. Default memory settings are not enough.)
This will download all project plug-ins, resolve dependencies and determine if your environment is set up properly. If all goes well, you should see the following message: Server running. Browse to http://localhost:8080/cdrlite
Open a browser if your choice and enter http://localhost:8080/cdrlite
You may log in with the following test accounts:
If you run into errors, try the following:
Grails upgrade (say yes)
The CDR was originally developed in the NetBeans IDE against Oracle XE. This version is using PostgreSQL 9.3.