diff --git a/pkgs/applications/graphics/meshlab/default.nix b/pkgs/applications/graphics/meshlab/default.nix
index bd5dea8014d6cd..9733f1e2efa07a 100644
--- a/pkgs/applications/graphics/meshlab/default.nix
+++ b/pkgs/applications/graphics/meshlab/default.nix
@@ -1,13 +1,53 @@
-{ fetchFromGitHub, libGLU, llvmPackages, qtbase, qtscript, qtxmlpatterns }:
+{ mkDerivation, lib, fetchFromGitHub
+, fetchpatch
+, libGLU
+, qtbase
+, qtscript
+, qtxmlpatterns
+, lib3ds
+, bzip2
+, muparser
+, levmar
+}:
 
 let
-  meshlabRev = "d596d7c086c51fbdfb56050f9c30b55dd0286d4c";
-  vcglibRev = "6c3c940e34327322507c703889f9f1cfa73ab183";
+  meshlabRev = "25f3d17b1d1d47ddc51179cb955f3027b7638745";
+  vcglibRev = "910da4c3e310f2e6557bd7a39c4f1529e61573e5";
   # ^ this should be the latest commit in the vcglib devel branch at the time of the meshlab revision
+  # We keep it separate here instead of using the `vcg` nix package because
+  # as of writing, meshlab upstream does not seem to follow a proper
+  # release process, and the other dependencies of `vcg` may no longer
+  # work when we upgrade it for the purpose of meshlab.
 
-  stdenv = llvmPackages.stdenv; # only building with clang seems to be tested upstream
-in stdenv.mkDerivation {
-  name = "meshlab-20180627-beta";
+  # Unfixed upstream compile error; see
+  #     https://github.com/cnr-isti-vclab/meshlab/issues/188#issuecomment-364785362
+  # that has with fixed line endings.
+  import_bundle_out_patch = fetchpatch {
+    name = "import_bundle_out.patch";
+    url = "https://aur.archlinux.org/cgit/aur.git/plain/import_bundle_out.patch?h=meshlab-git&id=f7250ea818470f07dc9b86726407091d39c0be6f";
+    sha256 = "1g6nli15i3fjd6jsgkxvb33kzbcv67xjkc3jv9r51lrwlm1ifzxi";
+  };
+
+  # Reduces amount of vendored libraries, fixes `/linux` vs `linux-g++`
+  # directory name linker errors.
+  external_patch = fetchpatch {
+    name = "external.patch";
+    url = "https://aur.archlinux.org/cgit/aur.git/plain/external.patch?h=meshlab-git&id=f7250ea818470f07dc9b86726407091d39c0be6f";
+    sha256 = "1rxwkxhmxis1420rc1w7dg89gkmym68lpszsq6snl6dzpl3ingsb";
+  };
+  _3ds_patch = fetchpatch {
+    name = "3ds.patch";
+    url = "https://aur.archlinux.org/cgit/aur.git/plain/3ds.patch?h=meshlab-git&id=f7250ea818470f07dc9b86726407091d39c0be6f";
+    sha256 = "1w435b7p1ggi2bzib4yyszmk54drjgpbn8n9mnsk1slsxnp2vmg8";
+  };
+  muparser_patch = fetchpatch {
+    name = "muparser.patch";
+    url = "https://aur.archlinux.org/cgit/aur.git/plain/muparser.patch?h=meshlab-git&id=f7250ea818470f07dc9b86726407091d39c0be6f";
+    sha256 = "1sf7xqwc2j8xxdx2yklwifii9qqgknvx6ahk2hq76mg78ry1nzhq";
+  };
+
+in mkDerivation {
+  name = "meshlab-20190129-beta";
 
   srcs =
     [
@@ -15,38 +55,54 @@ in stdenv.mkDerivation {
         owner = "cnr-isti-vclab";
         repo = "meshlab";
         rev = meshlabRev;
-        sha256 = "0xi7wiyy0yi545l5qvccbqahlcsf70mhx829gf7bq29640si4rax";
+        sha256 = "16d2i91hrxvrr5p0k33g3fzis9zp4gsy3n5y2nhafvsgdmaidiij";
         name = "meshlab-${meshlabRev}";
       })
       (fetchFromGitHub {
         owner = "cnr-isti-vclab";
         repo = "vcglib";
         rev = vcglibRev;
-        sha256 = "0jfgjvf21y9ncmyr7caipy3ardhig7hh9z8miy885c99b925hhwd";
+        sha256 = "0xpnjpwpj57hgai184rzyk9lbq6d9vbjzr477dvl5nplpwa420m1";
         name = "vcglib-${vcglibRev}";
       })
     ];
 
   sourceRoot = "meshlab-${meshlabRev}";
 
+  # Meshlab is not format-security clean; without disabling hardening, we get:
+  #     ../../external/qhull-2003.1/src/io.c:2169:3: error: format not a string literal and no format arguments [-Werror=format-security]
+  #        fprintf(fp, endfmt);
+  #        ^~~~~~~
   hardeningDisable = [ "format" ];
+
   enableParallelBuilding = true;
 
-  patches = [ ./fix-20180627-beta.patch ];
+  prePatch =
+    ''
+      # MeshLab has ../vcglib hardcoded everywhere, so move the source dir
+      mv ../vcglib-${vcglibRev} ../vcglib
 
-  buildPhase = ''
-    # MeshLab has ../vcglib hardcoded everywhere, so move the source dir
-    mv ../vcglib-${vcglibRev} ../vcglib
+      # Make all source files writable so that patches can be applied.
+      chmod -R u+w ..
+
+      patch -Np1 --directory=../vcglib -i ${import_bundle_out_patch}
 
+      patch -Np1 -i ${external_patch}
+      # Individual libraries
+      patch -Np1 -i ${_3ds_patch}
+      patch -Np1 -i ${muparser_patch}
+    ''
+    ;
+
+  buildPhase = ''
     cd src
     export NIX_LDFLAGS="-rpath $out/opt/meshlab $NIX_LDFLAGS"
-    export QMAKESPEC="linux-clang"
 
     pushd external
-    qmake -recursive external.pro
+    qmake -recursive $QMAKE_FLAGS external.pro
     buildPhase
     popd
-    qmake -recursive meshlab_full.pro
+    qmake -recursive $QMAKE_FLAGS meshlab_full.pro
     buildPhase
   '';
 
@@ -57,13 +113,22 @@ in stdenv.mkDerivation {
     ln -s $out/opt/meshlab/meshlabserver $out/bin/meshlabserver
   '';
 
-  buildInputs = [ libGLU llvmPackages.openmp qtbase qtscript qtxmlpatterns ];
+  buildInputs = [
+    libGLU
+    qtbase
+    qtscript
+    qtxmlpatterns
+    lib3ds
+    bzip2
+    muparser
+    levmar
+  ];
 
   meta = {
     description = "A system for processing and editing 3D triangular meshes.";
     homepage = http://www.meshlab.net/;
-    license = stdenv.lib.licenses.gpl3;
-    maintainers = with stdenv.lib.maintainers; [viric];
-    platforms = with stdenv.lib.platforms; linux;
+    license = lib.licenses.gpl3;
+    maintainers = with lib.maintainers; [viric];
+    platforms = with lib.platforms; linux;
   };
 }
diff --git a/pkgs/applications/graphics/meshlab/fix-20180627-beta.patch b/pkgs/applications/graphics/meshlab/fix-20180627-beta.patch
deleted file mode 100644
index 177b8e90c57430..00000000000000
--- a/pkgs/applications/graphics/meshlab/fix-20180627-beta.patch
+++ /dev/null
@@ -1,25 +0,0 @@
-diff --git a/src/meshlabplugins/edit_paint/paintbox.cpp b/src/meshlabplugins/edit_paint/paintbox.cpp
-index 2097a5b..6bcd1a4 100644
---- a/src/meshlabplugins/edit_paint/paintbox.cpp
-+++ b/src/meshlabplugins/edit_paint/paintbox.cpp
-@@ -23,6 +23,7 @@
- 
- #include "paintbox.h"
- #include <QFileDialog>
-+#include <QAction>
- 
- Paintbox::Paintbox(QWidget * parent, Qt::WindowFlags flags) : QWidget(parent, flags)
- {
-diff --git a/src/meshlabplugins/render_gdp/shaderDialog.h b/src/meshlabplugins/render_gdp/shaderDialog.h
-index a62d3b5..7eb1594 100644
---- a/src/meshlabplugins/render_gdp/shaderDialog.h
-+++ b/src/meshlabplugins/render_gdp/shaderDialog.h
-@@ -32,6 +32,8 @@
- #include "shaderStructs.h"
- #include "ui_shaderDialog.h"
- #include <QMap>
-+#include <QSlider>
-+#include <QLineEdit>
- 
- class QGLWidget;
-