Open Systems Pharmacology

Repositories

• OSP-PBPK-Model-Library

  Library of released PBPK substance models and evaluation reports
  3 1 1 0 Updated May 29, 2020

• OSPSuite-R

  R package for the OSPSuite
  R 0 0 27 1 Updated May 29, 2020

• OSPSuite.Core

  Core functionalities of the Open Systems Pharmacology Suite

  suite-components
  C# 6 2 61 0 Updated May 29, 2020

• Midazolam-Model

  Whole-body PBPK model of midazolam as CYP3A4 DDI victim drug

  ddi pbpk osp-model pk-sim
  MATLAB 4 0 0 0 Updated May 29, 2020

• OSPSuite.ReportingEngine

  R implementation of the reporting engine
  R 2 0 61 2 Updated May 28, 2020

• Qualification-DDI-CYP3A4

  Qualification of OSP platform for CYP3A4-mediated DDI
  MATLAB 5 0 0 0 Updated May 27, 2020

• Qualification-DDI-UGT

  Qualification of UGT-mediated drug-drug interactions

  ddi osp-qualification
  MATLAB 1 0 0 0 Updated May 27, 2020

• Database-for-observed-data

  Forked from NinaHanke/Database-for-observed-data

  Database for published pharmacokinetic data
  R 2 0 1 0 Updated May 26, 2020

• Qualification-text-modules
  3 0 0 0 Updated May 26, 2020

• Alfentanil-Model

  Whole-body PBPK model of alfentanil as CYP3A4 DDI victim drug

  ddi pbpk osp-model pk-sim
  MATLAB 3 0 2 0 Updated May 26, 2020

• MoBi

  MoBi® is a software tool for multiscale physiological modeling and simulation

  mobi suite-components
  C# 5 12 126 0 Updated May 25, 2020

• PK-Sim

  PK-Sim® is a comprehensive software tool for whole-body physiologically based pharmacokinetic modeling

  suite-components pk-sim
  C# 29 40 260 0 Updated May 25, 2020

• Efavirenz-Alfentanil-DDI

  Modeling of published clinical Efavirenz-Alfentanil-DDI studies for model evaluation

  osp-model
  1 0 0 0 Updated May 25, 2020

• Efavirenz-Midazolam-DDI

  Modeling of published clinical Efavirenz-Midazolam-DDI studies for model evaluation

  osp-model
  1 0 0 0 Updated May 25, 2020

• Pediatric_Qualification_Package_CYP3A4_Ontogeny

  Pediatric Qualification Package for CYP3A4 Ontogeny

  osp-qualification
  MATLAB 1 0 3 0 Updated May 25, 2020

• Pediatric_Qualification_Package_CYP2C8_Ontogeny

  Pediatric Qualification Package for CYP2C8 Ontogeny

  osp-qualification
  MATLAB 1 1 3 0 Updated May 25, 2020

• Efavirenz-Model

  Whole-body PBPK model of efavirenz as CYP3A4 perpetrator drug

  osp-model
  MATLAB 1 0 0 0 Updated May 25, 2020

• Verapamil-Model

  Verapamil PBPK model (parent only)
  MATLAB 3 0 0 0 Updated May 25, 2020

• Fluvoxamine-Midazolam-DDI

  Modeling of published clinical Fluvoxamine-Midazolam-DDI studies for model evaluation

  ddi pbpk osp-model pk-sim
  1 0 0 0 Updated May 25, 2020

• Fluvoxamine-Alprazolam-DDI

  osp-model
  0 0 0 0 Updated May 25, 2020

• Clarithromycin-Triazolam-DDI

  Modeling of published clinical Clarithromycin-Triazolam-DDI studies for model evaluation

  osp-model
  1 0 0 0 Updated May 25, 2020

• Clarithromycin-Midazolam-DDI

  Modeling of published clinical Clarithromycin-Midazolam-DDI studies for model evaluation

  ddi pbpk osp-model pk-sim
  1 1 0 0 Updated May 25, 2020

• Erythromycin-Triazolam-DDI

  osp-model
  1 0 0 0 Updated May 25, 2020

• Verapamil-Midazolam-DDI

  Forked from sfrechen/Verapamil-Midazolam-DDI

  Modeling of published clinical Verapamil-Midazolam-DDI studies for model evaluation
  2 0 0 0 Updated May 25, 2020

• Erythromycin-Midazolam-DDI

  osp-model
  1 0 0 0 Updated May 25, 2020

• Erythromycin-Alprazolam-DDI

  osp-model
  1 0 0 0 Updated May 25, 2020

• Itraconazole-Triazolam-DDI

  Modeling of published clinical Itraconazole-Triazolam-DDI studies for model evaluation

  osp-model
  0 0 0 0 Updated May 25, 2020

• Pediatric_Qualification_Package_GFR_Ontogeny

  Pediatric Qualification Package for GFR Ontogeny

  osp-qualification
  MATLAB 2 0 0 0 Updated May 25, 2020

• Itraconazole-Alprazolam-DDI

  Modeling of published clinical Itraconazole-Alprazolam-DDI studies for model evaluation

  osp-model
  1 0 0 0 Updated May 25, 2020

• Rifampicin-Triazolam-DDI

  Modeling of published clinical Rifampicin-Triazolam-DDI studies for model evaluation

  osp-model
  0 0 0 0 Updated May 25, 2020