Skip to content
PBPK Workshop at ACoP 10 2019
Branch: master
Clone or download
Fetching latest commit…
Cannot retrieve the latest commit at this time.
Type Name Latest commit message Commit time
Failed to load latest commit information. Update Jun 18, 2019

ACoP 10 PBPK Workshop 2019

PK-Sim® & MoBi® (OSP Suite) workshop on PBPK

esqLABS is running a one-day hands-on PK-Sim® & MoBi® workshop on basic concepts in PBPK on Thursday 24th of October in Orlando, US as a satellite meeting to ACoP 10. The workshop covers age-dependent PK, population simulations and drug-drug-interactions (DDI) in PBPK modeling using PK-Sim for DMPK, pediatric and geriatric investigations by leveraging physiological and mechanistic knowledge for translational modeling in your drug R&D program. During hands-on exercises you will learn how to:

  • Build a PBPK model in PK-Sim and compare to observed data
  • Learn how to consider age-dependency in drug PK in PK-Sim (Pediatrics and Geriatrics)
  • Conduct parameter identifications in PK-Sim and MoBi
  • Conduct population simulations in PK-Sim
  • Learn how to model drug-drug interactions in PK-Sim (DDI)

and, if time permits:

  • Simulate your PBPK model in R

This workshop will be held by consultants & scientists from esqlabs GmbH with extensive experience in the use of PK-Sim® & MoBi® in all application areas.

While the workshop does not require any prior experience with PK-Sim® & MoBi®, many topics will be of interest even for advanced users.


To register for the workshop, please visit EventBrite.

The workshop is currently restricted to 25 participants.

Registration includes coffee- and lunch breaks.


As a use-case for above learnings, we will develop PBPK models for different small molecule drugs as use-cases for modeling drug-drug interactions and the concepts of age-related PK, in detail:

Time (Thursday Oct 24) Topic
9:00 Welcome and getting everyone started (solving IT issues)
9:30 Lecture: Introduction to PBPK modeling and the OSP Suite (PK-Sim® & MoBi®)
10:00 Hands-On: Setting up a simple PBPK model
10:45 Coffee Break
11:00 Lecture: General concepts of PBPK modeling
11:30 Lecture: PBPK for drug-drug interactions (DDI) with PK-Sim®
12:00 Lunch Break
13:00 Hands-On: Modeling drug-drug interactions (DDI) with PK-Sim®
14:45 Lecture: Special populations – pediatrics and elderly
15:15 Coffee Break
15:30 Hands-On: Age Dependence of Pharmacokinetics (Population Simulations)
16:30 Wrap-up and Q & A
17:00 END


BRING YOUR OWN LAPTOPS! We will be doing hands-on work!

  • To download the software (WINDOWS ONLY!), please click here
  • Download & install the R distribution (Ver 3.5+; 64 Bit) from here
  • Download & install FREE RStudio Desktop (a GUI for R with additional functionalities for e.g. debugging and code visualization) from here
  • For starters, please check out the tutorial site (videos & hands-on) here


  • Please add this site to your watchlist (very top of page) to be informed of any changes.

Visit our News & Events Section for info on additional workshops in the future and news on our future developments in physiologically-based quantitative-systems-pharmacology.

Best Regards,

Stephan Schaller
(Managing Director, esqLABS GmbH)

You can’t perform that action at this time.