Discussions: Open-Systems-Pharmacology/Forum

Discussions

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  Code to input simulation into MoBi

  rachudso asked Feb 1, 2023 in Questions & Problems · Unanswered

  

  

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  Calculation surface areas not comprehensible

  davbus asked Jun 30, 2020 in Questions & Problems · Answered

  

  

  

  

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  Parameter identification Vmax and Km in PK-Sim 11

  Mwilaputa asked Jan 29, 2023 in Questions & Problems · Unanswered

  

  

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  Question about specific clearance calculation

  Sawy25 asked Jan 19, 2023 in Questions & Problems · Unanswered

  

  

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  Change Solver Settings via R

  Erik-Sjogren asked Jan 24, 2023 in Questions & Problems · Answered

  

  

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  How to express metabolizing enzymes in PK-SIM for Vmax, Km data by HLM

  Cheruvh asked Jan 11, 2023 in Questions & Problems · Unanswered

  

  

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  Formulas in "Molecule properties" are not copied over with Top container

  moPellowe asked Jan 18, 2023 in Questions & Problems · Unanswered

  

  

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  Location of "Partition coefficient (interstitial/water)"

  moPellowe asked Jan 18, 2023 in Questions & Problems · Answered

  

  

  

  

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  Metabolizing enzyme for an ADC model

  he-kadry asked Jan 13, 2023 in Questions & Problems · Unanswered

  

  

  

  

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  How to make the parent drug not inhibit its metabolite

  balamo98 asked Jan 16, 2023 in Questions & Problems · Answered

  

  

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  Hepatic impairment population

  SCZ1174 asked Oct 17, 2022 in Questions & Problems · Answered

  

  

  

  

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  Getting reaction diffusion rates from pbpk model

  sm1216 asked Jan 11, 2023 in Questions & Problems · Unanswered

  

  

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  Finding diffusion reaction rates.

  sm1216 asked Jan 11, 2023 in Questions & Problems · Unanswered

  

  

  

  

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  In MOBI, the "dialysis" constructed by the "event" module has no effect on the drug clearance rate and blood drug concentration

  JiaojiaoChen123 asked Dec 7, 2022 in Questions & Problems · Unanswered

  

  

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  How to estimate “mucosa permeability on basolateral side”

  balamo98 asked Jan 5, 2023 in Questions & Problems · Answered

  

  

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  Endosomal clearance of ligand-FcRn complex in the large molecule model

  moPellowe asked Jan 6, 2023 in Questions & Problems · Answered

  

  

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  Reaction building block for large molecule model

  moPellowe asked Jan 6, 2023 in Questions & Problems · Answered

  

  

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  Parameter values not getting shown in Simulation output

  Gautamvj asked Jul 22, 2022 in How-Tos · Unanswered

  

  

  

  

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  Gender Identification Following Export of Population Simulation Data

  SayeedMo asked Jan 4, 2023 in Questions & Problems · Unanswered

  

  

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  Transport Proteins Process Type selection

  miyayayayaa asked Jan 4, 2023 in Questions & Problems · Unanswered

  

  

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  Time profile analysis predicted line

  safgren asked Jan 2, 2023 in Questions & Problems · Answered

  

  

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  Questions about transfer protein and enzyme settings

  SCZ1174 asked Jan 3, 2023 in Questions & Problems · Unanswered

  

  

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  Pregnant PBPK

  AbilashReddybathini asked Jan 3, 2023 in Questions & Problems · Answered

  

  

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  About diltiazem PBPK model

  balamo98 asked Dec 27, 2022 in Questions & Problems · Answered

  

  

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  cancer popolation and demography

  WTY-tt asked Nov 16, 2022 in Questions & Problems · Unanswered

  

  

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