Skip to content

/ Forum

📢
Announcement Published: Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials @Yuri05 Yuri05
📢
Announcement Published: A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions @sfrechen sfrechen
New
Top: All
Today
Past week
Past month
Past year
All
Answered Unanswered
Label
Filter by label

Use alt + click/return to exclude labels.
You must be logged in to vote
1
❓
Exchanging observed data files between projects
wilbertdew asked Jul 15, 2021 in Questions & Problems · Answered
@wilbertdew @Yuri05 @PavelBal
@wilbertdew @Yuri05 @PavelBal
5
You must be logged in to vote
1
❓
why the uncompetitve inhibiton seem to be wrong, when i change the Ki of uncompetitive inhibition, there is no change of AUC of viticim?
dongji1982 asked Jul 1, 2021 in Questions & Problems · Unanswered
@dongji1982 @prvmalik
@dongji1982 @prvmalik
1
You must be logged in to vote
1
❓
What are your approaches for modeling oral absorption with late Tmax?
prvmalik asked Jul 24, 2021 in Questions & Problems · Unanswered
@prvmalik
@prvmalik
0
You must be logged in to vote
1
❓
ELF concentrations of large molecules using MoBi?
RobinM92 asked Jul 1, 2021 in Questions & Problems · Unanswered
@RobinM92 @Erik-Sjogren
@RobinM92 @Erik-Sjogren
1
You must be logged in to vote
1
❓
MoBi- Adding compartment to the model and connecting it to the molecule
Sanjana2697 asked Jul 12, 2021 in Questions & Problems · Unanswered
@Sanjana2697 @wilbertdew
@Sanjana2697 @wilbertdew
2
You must be logged in to vote
1
❓
The Fraction absorbed value was exceed 1 when it was simulated using EHC parameters.
hjhj112233 asked Jul 12, 2021 in Questions & Problems · Unanswered
@hjhj112233 @tobiasK2001
@hjhj112233 @tobiasK2001
1
You must be logged in to vote
1
❓
question of building a new population
tztz117 asked Jul 13, 2021 in Questions & Problems · Unanswered
@tztz117
@tztz117
0
You must be logged in to vote
1
❓
OSPSuite-R ERROR in R4.1.0
yangpluszhu asked Jul 8, 2021 in Questions & Problems · Unanswered
@yangpluszhu @Yuri05
@yangpluszhu @Yuri05
7
You must be logged in to vote
1
❓
Accessing Expression DB expression values outside of PKSim
mlinakisREH asked Jul 7, 2021 in Questions & Problems · Unanswered
@mlinakisREH
@mlinakisREH
0
You must be logged in to vote
1
📢
Published: A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions
sfrechen started Jul 7, 2021 in Announcement
@sfrechen
@sfrechen
0
You must be logged in to vote
2
📢
Published: Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials
Yuri05 started Jul 1, 2021 in Announcement
@Yuri05
@Yuri05
0
You must be logged in to vote
2
🚀
Saturable plasma protein binding model
AlejandraSchiavo asked Jun 2, 2021 in Models · Answered
@AlejandraSchiavo @msevestre @StephanSchaller
@AlejandraSchiavo @msevestre @StephanSchaller
10
You must be logged in to vote
1
❓
Inhalation of a macromolecule in preclinical species
RobinM92 asked Jun 18, 2021 in Questions & Problems · Unanswered
@RobinM92 @moPellowe
@RobinM92 @moPellowe
3
You must be logged in to vote
1
#️⃣
How to create 1 observer 'total fraction of dose' for multiple molecules/enzymes
nina-nauwelaerts asked Jun 22, 2021 in How-Tos · Answered
@nina-nauwelaerts @Yuri05
@nina-nauwelaerts @Yuri05
1
You must be logged in to vote
1
❓
OSP-suite compatible with R4.1?
RobinM92 asked Jun 21, 2021 in Questions & Problems · Answered
@RobinM92 @PavelBal
@RobinM92 @PavelBal
2
You must be logged in to vote
1
❓
Run a simulation from command shell Window or Linux
jonathanlsn asked Jun 16, 2021 in Questions & Problems · Answered
@jonathanlsn @Yuri05
@jonathanlsn @Yuri05
3
You must be logged in to vote
1
❓
Observer for Fraction available after intestinal metabolism
teutonicod asked Mar 10, 2021 in Questions & Problems · Unanswered
@teutonicod @wilbertdew
@teutonicod @wilbertdew
1
You must be logged in to vote
1
❓
import data
fcobarahona asked Jun 15, 2021 in Questions & Problems · Unanswered
@fcobarahona @tobiasK2001
@fcobarahona @tobiasK2001
1
You must be logged in to vote
1
❓
Food effect overestimated
MSmodeler asked Jun 15, 2021 in Questions & Problems · Unanswered
@MSmodeler
@MSmodeler
0
You must be logged in to vote
1
❓
Protein binding to other protein than Albumin or alpha1-glycoprotein
MSmodeler asked Jun 8, 2021 in Questions & Problems · Unanswered
@MSmodeler @StephanSchaller
@MSmodeler @StephanSchaller
3
You must be logged in to vote
1
❓
Particle Dissolution/ Use as suspension
sariiiiii83 asked Jun 10, 2021 in Questions & Problems · Unanswered
@sariiiiii83 @AndreDlm
@sariiiiii83 @AndreDlm
1
You must be logged in to vote
1
❓
Help with validating new model structure/set-up after addition of new organ compartment?
eburg007 asked May 21, 2021 in Questions & Problems · Unanswered
@eburg007 @StephanSchaller
@eburg007 @StephanSchaller
1
You must be logged in to vote
1
#️⃣
drug-drug interaction by protein displacement in plasma in PK-Sim
mmalsmadi asked Jun 7, 2021 in How-Tos · Answered
@mmalsmadi @StephanSchaller
@mmalsmadi @StephanSchaller
2
You must be logged in to vote
1
❓
AUC ratio calculation in PK-Sim after multiple doses
teutonicod asked Jun 4, 2021 in Questions & Problems · Unanswered
@teutonicod
@teutonicod
0
You must be logged in to vote
1
❓
Link the skin compartment to the Venous blood compartment in whole body system
jonathanlsn asked Jun 3, 2021 in Questions & Problems · Unanswered
@jonathanlsn @abdullahhamadeh
@jonathanlsn @abdullahhamadeh
2