Open-Systems-Pharmacology / Forum Public

Discussions

• 1

  ❓

  VSS,MRT , pharmacokinetic steady state

  ranamjz asked Jan 24, 2022 in Questions & Problems · Unanswered

  

  

  1
• 1

  🚀

  What is the difference between the PKsim and Mobi?

  xiangetang asked Jan 24, 2022 in Models · Unanswered

  

  

  1
• 1

  ❓

  Incomplete Absorption

  ranamjz asked Jan 16, 2022 in Questions & Problems · Unanswered

  

  

  

  

  6
• 1

  ❓

  What are your approaches for modeling oral absorption with late Tmax?

  prvmalik asked Jul 24, 2021 in Questions & Problems · Unanswered

  

  

  

  

  5
• 1

  ❓

  Create individuals (and generate ontogeny factors) with custom ontogeny

  moPellowe asked Jan 13, 2022 in Questions & Problems · Answered

  

  

  

  

  22
• 1

  ❓

  Seeking General Method for Updating Transporter Concentration from 9.1 to 10

  prvmalik asked Jan 14, 2022 in Questions & Problems · Unanswered

  

  

  

  

  2
• 1

  ❓

  query about data export

  fcobarahona asked Jan 20, 2022 in Questions & Problems · Unanswered

  

  

  1
• 2

  📢

  New version of CYP3A4-DDI qualification report released

  sfrechen started Jan 16, 2022 in Announcement

  

  

  0
• 3

  📢

  Published: Development and Evaluation of an In Silico Dermal Absorption Model Relevant for Children

  abdullahhamadeh started Jan 12, 2022 in Announcement

  

  

  1
• 1

  ❓

  Evaporation after removal dose

  MelanieMartha26 asked Jan 12, 2022 in Questions & Problems · Unanswered

  

  

  1
• 1

  ❓

  Vehicle composition skin permeation model

  MelanieMartha26 asked Jan 11, 2022 in Questions & Problems · Unanswered

  

  

  1
• 2

  📢

  Carbamazepine PBPK model

  LMFuhr started Mar 30, 2021 in Announcement

  

  

  1
• 1

  ❓

  About the open sourse ?

  Carrie-nothing asked Jan 8, 2022 in Questions & Problems · Unanswered

  

  

  

  

  3
• 1

  ❓

  Expression database for rat?

  Carrie-nothing asked Jan 7, 2022 in Questions & Problems · Unanswered

  

  

  

  

  2
• 1

  ❓

  Finite dose

  MelanieMartha26 asked Jan 4, 2022 in Questions & Problems · Unanswered

  

  

  4
• 1

  #️⃣

  how to use the model to predict AUC, Cmax and Tmax

  LiuYX1998 asked Jan 5, 2022 in How-Tos · Unanswered

  

  

  1
• 1

  ❓

  PK-Parameter in Time Profile Analysis - multiple questions

  PavelBal asked Dec 17, 2021 in Questions & Problems · Unanswered

  

  

  

  

  15
• 1

  ❓

  File Format and CTD module for Regulatory Submission of PBPK report to US-FDA

  arketkar asked Dec 28, 2021 in Questions & Problems · Answered

  

  

  

  

  6
• 2

  ❓

  What are the factors that affect population simulation?

  Achineseman asked Dec 25, 2021 in Questions & Problems · Unanswered

  

  

  1
• 1

  ❓

  Plasma stability

  JennyLeeeee asked Dec 22, 2021 in Questions & Problems · Unanswered

  

  

  3
• 1

  ❓

  Log4j vulnerability

  rgullinibi asked Dec 20, 2021 in Questions & Problems · Answered

  

  

  1
• 1

  ❓

  Hello,

  OZaher asked Dec 14, 2021 in Questions & Problems · Answered

  

  

  2
• 1

  ❓

  In PK-Sim, can we rely on Vss to explain the overprediction of MRT in IV and Oral simulations?

  sajabzughoul asked Dec 13, 2021 in Questions & Problems · Unanswered

  

  

  3
• 1

  ❓

  Total fraction metabolized by CYPs with large molecule model

  teutonicod asked Dec 3, 2021 in Questions & Problems · Unanswered

  

  

  

  

  3
• 1

  ❓

  Support for project file of version 4.2 and older has ended

  DamoiseauxD asked Dec 10, 2021 in Questions & Problems · Unanswered

  

  

  

  

  2