Open-Systems-Pharmacology Forum Discussions

Discussions

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  How to obtain CV% in PK-sim or Mobi

  zjh112 asked Jun 3, 2023 in Questions & Problems · Unanswered

  

  

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  Enterohepatic Recirculation

  pburkat1 asked May 30, 2023 in Questions & Problems · Unanswered

  

  

  

  

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  Number of small and large pores on Mobi ?

  Salih-Benamara asked May 30, 2023 in Questions & Problems · Unanswered

  

  

  

  

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  Where is PK analysis button in MoBi ?

  Microbiotman asked May 30, 2023 in Questions & Problems · Answered

  

  

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  how to check the implementation of particle dissolution method of PKSIM

  hainiwen asked May 15, 2023 in Questions & Problems · Answered

  

  

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  probenecid PBPK model and conversion reference concentration v9- v11 PKsim

  paolamian01 asked May 25, 2023 in Questions & Problems · Unanswered

  

  

  

  

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  How does the model estimate Kprot

  rreissexp asked May 26, 2023 in Questions & Problems · Unanswered

  

  

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  Problem with ospsuite

  Sawy25 asked May 26, 2023 in Questions & Problems · Unanswered

  

  

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  How to set up the population with hepatic impairment version 11

  gapa84 asked May 24, 2023 in Questions & Problems · Unanswered

  

  

  

  

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  📢

  Quinidine PBPK model for CYP2D6, CYP3A4 and P-gp drug-drug(-gene) interaction predictions

  DeniTue started May 25, 2023 in Announcement

  

  

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  Building Block Explorer and Simulation Explorer are not shown in MoBi Portable V11.2

  GhazalMontaseri asked May 22, 2023 in Questions & Problems · Answered

  

  

  

  

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  About sensitivity analysis output

  Sawy25 asked May 24, 2023 in Questions & Problems · Answered

  

  

  

  

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  use PKsim or Mobi to establish PBPK model, with the purpose of predicting brain tissue concentration through blood concentration of the two drugs to optimize the drug administration plan

  pearlzhuzhu asked May 24, 2023 in Questions & Problems · Unanswered

  

  

  

  

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  Installation problem PK-Sim on Windows 11 on Mac (with Parallels)

  MillaKerpenkath asked May 24, 2023 in Questions & Problems · Unanswered

  

  

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  How dose Intrinsic clearance – First order method caculate the hepatic clearance?

  margotqiu asked May 24, 2023 in Questions & Problems · Unanswered

  

  

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  Upload of Physiology parameter for a Cat and Cattle model

  KirstenBoerngen asked Aug 18, 2021 in Models · Unanswered

  

  

  

  

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  #️⃣

  MDCKII-MDR1 transporter Papp

  RajFer asked Feb 27, 2023 in How-Tos · Unanswered

  

  

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  How to combine the different simulation into one model?

  Atekton asked May 22, 2023 in Questions & Problems · Unanswered

  

  

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  Recovering projects and avoiding software crashes with large amount of data

  AyaSaleh90 asked May 19, 2023 in Questions & Problems · Unanswered

  

  

  

  

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  Mobi Display

  Salih-Benamara asked Feb 24, 2022 in Questions & Problems · Answered

  

  

  

  

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  How the results of the simulation in MOBI are used for PK analysis？

  ytg922 asked Apr 15, 2022 in Questions & Problems · Unanswered

  

  

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  How to define subcompartmental water distribution of each organ in the MoBi interface

  tjj870520 asked May 19, 2023 in Questions & Problems · Unanswered

  

  

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  what dose Time < T_lag ? 0 : k_a*A_ET mean (Expression in Mobi or PKSIM)

  hainiwen asked May 17, 2023 in Questions & Problems · Answered

  

  

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  How to add new administration route, such as: Intra-articular injection ?

  lynnieyang asked May 12, 2023 in Questions & Problems · Unanswered

  

  

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  Generate Compounds from SMILES/InChi

  yoni03 asked May 15, 2023 in Questions & Problems · Unanswered

  

  

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