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If you intend to open a discussion in the Open Systems Pharmacology Forum, you need to visit the "issues" (https://github.com/Open-Systems-Pharmacology/Forum/issues). In the upper right, you find a green button "New issue", which you need to press in order to get to a window, that allows you to describe your discussion topic. You can mark it with certain labels to classify it and make it easier to find for others.