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OSP Suite 7.2.1 released #105
New OSP Suite version 7.2.1 is released and can be downloaded here
Release Notes for the Open Systems Pharmacology Suite 7.2.1
Dosage per Body Surface Area
Body surface area-based dosing is now available in PK-Sim.
Based on a recent literature review on anatomical and physiological changes during pregnancy, a pregnancy population PBPK model was built (s. articles by André Dallmann et al.).
In the figure below, a summary of the pregnancy-induced changes in mean organ volumes (A) and maternal organ blood flows (B) from gestational week 2 to gestational week 40 where term pregnancy is reached are illustrated. The first 2 weeks preceding conception at the beginning of gestational week 3 are lightened.
Ready to use pregnancy models
Major improvement of chart performance
In some cases (e.g. adding large amount of observed data sets simultaneously) chart performance was not optimal. In the current version the overall chart performance was significantly increased.
Individuals within Populations
The population analysis plots were improved to:
Example: identify individuals in a Box-Whisker plot of a population simulation
Example: extract individuals from a Box-Whisker plot in a population simulation
Example: extract individuals from a population building block
Parameter Identification: Fixed parameters
It is now possible to fix parameter values during parameter identification
Draft watermark support
Now it is possible to clearly identify preliminary version of plots when using "Copy to clipboard" action.
(Experimental) Portable versions of PK-Sim and MoBi
Starting with 7.2 release of the OSP Suite it is possible to use PK-Sim and MoBi as portable versions without installation. These portable versions can also be used parallel to another versions of the OSP Suite.
How to use portable versions
and many more... (visit the 7.2.1 download page for the full list)