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Create variability in Plasma Clearance #304
Hello OSP Forum !
I am trying to create a population of mice. I don't have any metabolizing enzymes information on my drug so I can't create a variability in term of these. However I would need to create a variability of the Total Hepatic Clearance -> "Plasma clearance"
Thank you !
Dear @RobinPharma RobinPharma,
Now in your population you can alter the expression level of the hepatic enzyme and create your clearance variability.
Does this help you?