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Need instruction and advice for building a new PKSim population. #307

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regulus92 opened this Issue Apr 12, 2019 · 3 comments

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@regulus92
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regulus92 commented Apr 12, 2019

Hello. Here I intend to creat a new population for PKSim, i.e., Chinese Han population. Since I am still learning Mobi, may I get some advices from you guys? Any comment welcome. Thank you.

@Yuri05 Yuri05 added the help wanted label Apr 12, 2019

@AndreDlm

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AndreDlm commented Apr 12, 2019

Hi @regulus92 ,

in MoBi you can only simulate one individual, but not populations (which is what you want to do, I assume?). If you are interested in population simulations, you need to do this in PK-Sim.

You may use the ICRP Extended population as a kind of "dummy" population in which change the anatomical and physiological parameters so that they reflect those observed in, e.g. a Chinese Han population. You can find more info here

Maybe this helps.

@PavelBal

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PavelBal commented Apr 12, 2019

If I understood correctly, @regulus92 wants to contribute by developing new population, i.e., providing data on physiology etc?

@regulus92

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regulus92 commented Apr 13, 2019

@PavelBal Exactly

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