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BCS 2 weak base - precipitation kinetics in the lumen #309
Is it possible to handle precipitation kinetics in case of BCS 2 weak bases using PK-Sim, e.g. at least as a first order process? I am aware that by treating precipitated drug as "soluble", the precipitated drug amount is added to the solid drug mass, increasing Xsolid available to dissolution. But I was wondering whether it is possible to set/handle precipitation rate constant and supersaturation directly.
Thanks in advance
All the best
If you would like to change the kinetics itself (to first order or whatever), you can do it only via MoBi: