Set fu as a function of two proteins

[itroconiz]

The equation I would like to use in my PKsim model is:

fu=Kd1 x Kd2/(L1 x AAG x Kd2+L2 x Alb x Kd1+Kd1+Kd2)
Where AAG and ALB stand for concentrations of alpha1-acid glycoprotein, and albumin, respectively.
L1 and L2 are scaling factor (known), and Kd2 equilibrium constants (known)

[StephanSchaller]

You would have to move to MoBi to do this. Is this an option for you?
There, you could define "Fraction unbound (plasma, reference value)" (a Parameter of your molecule) as a formula.
NOTE: this will also have an effect on your partitioning coefficient calculations!

Best,
Stephan