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Propofol and (Nor-)Adrenaline PBPK Model #433
Hi, Stephen. I found two PBPK reports for propofol.
Hi Stephen, As you know I constructed the PBPK model in the first reference of Liang, it's in Simcyp. If you need any more information about the model or input parameters, feel free to ask me :) Kind regards, Robin Am 13.12.2019 um 04:22 schrieb Liang Zheng:…
Hi, Stephen. I found two PBPK reports for propofol. 1. Michelet R, Van Bocxlaer J, Allegaert K, Vermeulen A. The use of PBPK modeling across the pediatric age range using propofol as a case. J Pharmacokinet Phar. 2018;45(6):765-85. 2. Gill KL, Gertz M, Houston JB, Galetin A. Application of a physiologically based pharmacokinetic model to assess propofol hepatic and renal glucuronidation in isolation: utility of in vitro and in vivo data. Drug Metab Dispos. 2013;41(4):744-53. Regards, Liang — You are receiving this because you are subscribed to this thread. Reply to this email directly, view it on GitHub <#433?email_source=notifications&email_token=AHKFXQ7JXFT4DO3JGPG4TWLQYL5VXA5CNFSM4JZ7374KYY3PNVWWK3TUL52HS4DFVREXG43VMVBW63LNMVXHJKTDN5WW2ZLOORPWSZGOEGYY3GI#issuecomment-565284249>, or unsubscribe <https://github.com/notifications/unsubscribe-auth/AHKFXQZC5DHY6YJKJG3QTU3QYL5VXANCNFSM4JZ7374A>.