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input of Clint measurement for blood and liver? #459

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PriKalra opened this issue Feb 12, 2020 · 0 comments
Open

input of Clint measurement for blood and liver? #459

PriKalra opened this issue Feb 12, 2020 · 0 comments

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@PriKalra
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@PriKalra PriKalra commented Feb 12, 2020

Dear All,

I have Clint measurements from liver microsomes (Unit: ml/min/mg) and also from blood incubation (Unit: ml/min)

I have incorporated the liver microsome clearance value as metabolising enzymes -> In vitro metabolic rate in the presence of liver microsomes First order

However, I am lost with how would I incorporate the value of blood incubation?

Best,
Pri

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