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Unable to capture Absorption & elimination phase #81
Sorry it is a bit hard for me to answere your question from the info provided.
I am dealing with Extended Release formulation (Animal study: Beagle) having,
I can't share all details as it is Confidential.
I am not at all able to capture absorption and elimination. This is my first attempt of M&S, So I don't have any idea which parameters need to be adjusted/modified.
Do you have IV data? Then start with this model first to understand distribution and clearance processes. Once you have a good understanding and the IV model describes your data, It's time to look at absorption and PO models.