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Experience with PBPK modells for aminoglykoside antibiotics? #85
Dear all, I wonder If you had came across of examples of PBPK modells for aminoglykoside antibiotics using PK-sim and /or MoBi? Are ther more than these?
Of special interest maybe: could tissue concentrations be predicted succesfully in e.g. kidney, ZNS or else. Did special issues / problems arouse? What data were critical to inform the model?
Please let me know your suggestions.