Skip to content
QSPC2020 satellite workshops: PK-Sim® & MoBi® hands-on training for PBPK and PBPK-based QSP in Leiden, Netherlands (April 21st and 25th) (www.esqlabs.com/news-events)
Branch: master
Clone or download
Fetching latest commit…
Cannot retrieve the latest commit at this time.
Permalink
Type Name Latest commit message Commit time
Failed to load latest commit information.
README.md

README.md

OSP Suite Workshops at QSP Conference in Leiden, Netherlands (April 21st and 25th, 2020)

Two 1-Day PK-Sim® & MoBi® workshops on PBPK and PBPK-based QSP

esqLABS is running two hands-on PK-Sim® & MoBi® workshops on PBPK and PBPK-based QSP on Tuesday and Saturday 21st and 25th of April 2020 as (pre & post) satellite meetings to the QSPC 2020 Meeting in Leiden, Netherlands.

The workshops cover the basics of PBPK and concepts and application of combining PK-Sim, MoBi and R to build your very own digital platforms for the prediction of clinical trial outcomes by leveraging physiological and mechanistic knowledge to translate early in-vitro and preclinical outcomes to the clinic.

Within the two workshops, you will learn how to:

Workshop 1 / Day 1:

  • Build a PBPK model in PK-Sim and compare to observed data
  • Learn how to model drug-drug interactions in PK-Sim (DDI)
  • Learn how to consider age-dependency in drug PK in PK-Sim (Pediatric Analyses)
  • Conduct population simulations in PK-Sim and MoBi

Workshop 2 /Day 2:

  • Integrate mechanism-based pharmacodynamics in MoBi
  • Conduct parameter identifications in PK-Sim and MoBi
  • Simulate and analyze your PBPK-QSP model in R

The two workshops will be held by the consultants and scientists from esqlabs GmbH with extensive experience in the use of PK-Sim® & MoBi® in all application areas.

While the workshop does not require any prior experience with PK-Sim® & MoBi®, many topics will be of interest even for advanced users.

LOCATION

Workshop 1 PBPK (April 21, 2020)

Golden Tulip Hotel Schipholweg 3 2316 XB Leiden, Netherlands

Workshop 2 PB-QSP (April 25, 2020)

Fletcher Wellness-Hotel Leiden Bargelaan 180 2333 CW Leiden, Netherlands

REGISTRATION

You can register for each workshop separately or for both at a reduced price.

You can Register on Eventbrite:

  • Register and select either: DAY 1 only, DAY 2 only, or BOTH days.

Each workshop day is currently restricted to 15 participants.

Registration includes coffee- and lunch breaks.

AGENDA

The use-cases within the workshops will be based on published examples.

We will develop PBPK models for small molecules for DDI and pediatric populations and PBPK models for biologics (antibody-drug conjugates (AsDC)), which we develop into a PB-QSP model for treatment of tumor growth.

The two workshop days are scheduled as follows:

Day 1 (21st April, 2020)

Agenda Day 1

Day 2 (25th April, 2020)

Agenda Day 2

PREPARATION

  • BRING YOUR OWN LAPTOPS, pre-installed with the software! We will be doing hands-on work!

  • To download the software, please click here

  • Download & install the R distribution (Ver 3.5+) from here

  • Download & install FREE RStudio Desktop (a GUI for R with additional functionalities for e.g. debugging and code visualization) from here

  • For starters, please check out the tutorial site (videos & hands-on) here

NOTES

  • Please add this site to your watchlist (very top of page) to be informed of any changes.

Visit our News & Events Section for info on additional workshops in the future and news on our future developments in physiologically-based quantitative-systems-pharmacology.



Best Regards,

Stephan Schaller
(Managing Director, esqLABS GmbH)

You can’t perform that action at this time.