diff --git a/src/bindings/python/constraints.txt b/src/bindings/python/constraints.txt
index 48c94a4cdabcae..a3ff0e94daa0f6 100644
--- a/src/bindings/python/constraints.txt
+++ b/src/bindings/python/constraints.txt
@@ -1,7 +1,7 @@
 # used in multiple components
 onnx==1.13.1  # Python bindings, ONNX Frontend
 numpy>=1.16.6,<1.26  # Python bindings, frontends
-protobuf>=3.18.1,<4.0.0  # Python bindings, frontends
+protobuf>=3.18.1,<6.0.0  # Python bindings, frontends
 
 # pytest
 pytest>=5.0,<7.4