diff --git a/bin/resources/GameIndex.yaml b/bin/resources/GameIndex.yaml
index 8929aaa5c95da..340d074fb78d5 100644
--- a/bin/resources/GameIndex.yaml
+++ b/bin/resources/GameIndex.yaml
@@ -18328,6 +18328,11 @@ SLES-52563:
 SLES-52567:
   name: "Catwoman"
   region: "PAL-M7"
+  gsHWFixes:
+    recommendedBlendingLevel: 4 # Fixes bloom.
+    autoFlush: 1 # Fixes ghosting.
+    textureInsideRT: 1 # Required for offset RTs/textures for post-processing.
+    roundSprite: 2 # Fixes misaligned post-processing.
 SLES-52568:
   name: "Crash Twinsanity"
   region: "PAL-M5"
@@ -60461,6 +60466,11 @@ SLUS-20992:
   name: "Catwoman"
   region: "NTSC-U"
   compat: 5
+  gsHWFixes:
+    recommendedBlendingLevel: 4 # Fixes bloom.
+    autoFlush: 1 # Fixes ghosting.
+    textureInsideRT: 1 # Required for offset RTs/textures for post-processing.
+    roundSprite: 2 # Fixes misaligned post-processing.
 SLUS-20993:
   name: "Ghosthunter"
   region: "NTSC-U"
diff --git a/pcsx2/GS/Renderers/HW/GSRendererHW.cpp b/pcsx2/GS/Renderers/HW/GSRendererHW.cpp
index 08549831cc0fc..21b0dfb994f79 100644
--- a/pcsx2/GS/Renderers/HW/GSRendererHW.cpp
+++ b/pcsx2/GS/Renderers/HW/GSRendererHW.cpp
@@ -6592,6 +6592,24 @@ void GSRendererHW::ReplaceVerticesWithSprite(const GSVector4i& unscaled_rect, co
 	ReplaceVerticesWithSprite(unscaled_rect, unscaled_rect, unscaled_size, unscaled_rect);
 }
 
+void GSRendererHW::OffsetDraw(s32 fbp_offset, s32 zbp_offset, s32 xoffset, s32 yoffset)
+{
+	GL_INS("Offseting render target by %d pages [%x -> %x], Z by %d pages [%x -> %x]",
+		fbp_offset, m_cached_ctx.FRAME.FBP << 5, zbp_offset, (m_cached_ctx.FRAME.FBP + fbp_offset) << 5);
+	GL_INS("Offseting vertices by [%d, %d]", xoffset, yoffset);
+
+	m_cached_ctx.FRAME.FBP += fbp_offset;
+	m_cached_ctx.ZBUF.ZBP += zbp_offset;
+
+	const s32 fp_xoffset = xoffset << 4;
+	const s32 fp_yoffset = yoffset << 4;
+	for (u32 i = 0; i < m_vertex.next; i++)
+	{
+		m_vertex.buff[i].XYZ.X += fp_xoffset;
+		m_vertex.buff[i].XYZ.Y += fp_yoffset;
+	}
+}
+
 GSHWDrawConfig& GSRendererHW::BeginHLEHardwareDraw(
 	GSTexture* rt, GSTexture* ds, float rt_scale, GSTexture* tex, float tex_scale, const GSVector4i& unscaled_rect)
 {
diff --git a/pcsx2/GS/Renderers/HW/GSRendererHW.h b/pcsx2/GS/Renderers/HW/GSRendererHW.h
index 58ddeb3967c3f..f55cf38936f4b 100644
--- a/pcsx2/GS/Renderers/HW/GSRendererHW.h
+++ b/pcsx2/GS/Renderers/HW/GSRendererHW.h
@@ -217,6 +217,9 @@ class GSRendererHW : public GSRenderer
 	/// Returns true if the specified texture address matches the frame or Z buffer.
 	bool IsTBPFrameOrZ(u32 tbp) const;
 
+	/// Offsets the current draw, used for RT-in-RT. Offsets are relative to the *current* FBP, not the new FBP.
+	void OffsetDraw(s32 fbp_offset, s32 zbp_offset, s32 xoffset, s32 yoffset);
+
 	/// Replaces vertices with the specified fullscreen quad.
 	void ReplaceVerticesWithSprite(const GSVector4i& unscaled_rect, const GSVector4i& unscaled_uv_rect,
 		const GSVector2i& unscaled_size, const GSVector4i& scissor);
diff --git a/pcsx2/GS/Renderers/HW/GSTextureCache.cpp b/pcsx2/GS/Renderers/HW/GSTextureCache.cpp
index 315d4dc542561..b61f8a15a97f8 100644
--- a/pcsx2/GS/Renderers/HW/GSTextureCache.cpp
+++ b/pcsx2/GS/Renderers/HW/GSTextureCache.cpp
@@ -1541,6 +1541,18 @@ GSTextureCache::Source* GSTextureCache::LookupSource(const bool is_color, const
 							dst = t;
 							tex_merge_rt = false;
 							found_t = true;
+
+							// Catwoman offsets the RT as well as the texture.
+							if (GSRendererHW::GetInstance()->GetCachedCtx()->FRAME.Block() == TEX0.TBP0)
+							{
+								// Should be page aligned.
+								pxAssert(((t->m_TEX0.TBP0 - TEX0.TBP0) % 32) == 0);
+								const s32 page_offset = (t->m_TEX0.TBP0 - TEX0.TBP0) >> 5;
+								GL_CACHE("TC: RT also in front of TBP, offsetting draw by %d pages and [%d,%d].", page_offset, x_offset, y_offset);
+								GSRendererHW::GetInstance()->OffsetDraw(page_offset, page_offset, x_offset, y_offset);
+								break;
+							}
+
 							if (dst->m_TEX0.TBP0 == frame_fbp && possible_shuffle)
 								break;
 							else