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The following entries for CD45 isoforms in the Protein Ontology need to be related due to automated import of recent UniProt sequence entries related to CD45:
Although PR:0000001015 was initially created to represent the human CD45RA isoform, as there is evidence for a CD45RA isoform in chimpanzee and perhaps other species, it should remain as the parent term for this isoform. However, an inferred (or asserted) is_a relationship of PR:P08575-8 to PR:0000001015 needs to be created to reflect that PR:P08575-8 is the human specific form of PR:0000001015.
Also http://purl.obolibrary.org/obo/PR_P08575-8 should receive the exact synonym "CD45RA (human)" in line with the "CD45RA" synonym of the parent.
need to have a parent-child relationship for similar reasons. Currently PRO lists http://purl.obolibrary.org/obo/PR_P08575-2 as the human specific child of http://purl.obolibrary.org/obo/PR_000001017 but the UniProt entry for P08575 no longer includes a P08575-2 isoform.
This should be corrected in PRO.
Also http://purl.obolibrary.org/obo/PR_000001017 should receive the exact synonym "CD45RO" and http://purl.obolibrary.org/obo/PR_P08575-4 should receive the exact synonym "CD45RO (human)" in line with the "CD45RO" synonym of the parent.