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NTR: mucin #93

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nataled opened this issue Dec 2, 2013 · 1 comment
Open

NTR: mucin #93

nataled opened this issue Dec 2, 2013 · 1 comment
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@nataled nataled commented Dec 2, 2013

def: "Large glycoprotein with a high content of serine, threonine, and proline residues and numerous O-GalNAc-linked saccharides, often occurring in clusters on the polypeptide."[http://www.ncbi.nlm.nih.gov/books/NBK1932/]

See also: http://en.wikipedia.org/wiki/Mucin

Should all proteins in PRO like mucin-X be classified under here? Or only modified form? I think people would expect them to be classified here, maybe family grouping should be defined dispositionally?

Reported by: cmungall

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@nataled nataled commented Dec 11, 2013

This is an interesting case, complicated enough to warrant some discussion during our curators meeting. At first glance, it seems that mucins should indeed be defined dispositionally.

Original comment by: nataled

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