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FastSMC is a method to quickly and accurately estimate pairwise identical-by-descent (IBD) regions in the genome. FastSMC estimates the age of IBD segments and scales to large biobank datasets. https://doi.org/10.1038/s41467-020-19588-x

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PalamaraLab/FastSMC

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FastSMC

⚠️ This repository is deprecated ⚠️

All FastSMC functionality can now be found in ASMC together with improvements and bug fixes.

This repository contains FastSMC development history, and v1.0 is the initial public release corresponding to this paper:

J. Nait Saada, G. Kalantzis, D. Shyr, F. Cooper, M. Robinson, A. Gusev, P. F. Palamara. Identity-by-descent detection across 487,409 British samples reveals fine-scale evolutionary history and trait associations. Nature Communications, 2020.

If you want to use this specific repository, please refer to the legacy readme.

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FastSMC is a method to quickly and accurately estimate pairwise identical-by-descent (IBD) regions in the genome. FastSMC estimates the age of IBD segments and scales to large biobank datasets. https://doi.org/10.1038/s41467-020-19588-x

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