diff --git a/.github/workflows/testsuite.yml b/.github/workflows/testsuite.yml
index 79c5aaae57ff..3ca0511da291 100644
--- a/.github/workflows/testsuite.yml
+++ b/.github/workflows/testsuite.yml
@@ -263,6 +263,7 @@ jobs:
           - "-Duserelocatableinc"
           - "-Dcc='clang'"
           - "-Dcc='g++'"
+          - "-Accflags=-DSILENT_NO_TAINT_SUPPORT"
 
     steps:
       - name: Install System dependencies
diff --git a/lib/locale.t b/lib/locale.t
index 66dcf057932c..00cb43f15870 100644
--- a/lib/locale.t
+++ b/lib/locale.t
@@ -36,7 +36,9 @@ my $is_ebcdic = ord("A") == 193;
 my $os = lc $^O;
 
 # Configure now lets you build a perl that silently ignores taint features
-my $NoTaintSupport = exists($Config{taint_support}) && !$Config{taint_support};
+my $NoTaintSupport =
+    (exists($Config{taint_support}) && !$Config{taint_support}) ||
+    $Config{ccflags} =~ /-DSILENT_NO_TAINT_SUPPORT/;
 
 no warnings 'locale';  # We test even weird locales; and do some scary things
                        # in ok locales
diff --git a/lib/overload.t b/lib/overload.t
index adb57d3ee20d..ef10fa92ab2d 100644
--- a/lib/overload.t
+++ b/lib/overload.t
@@ -1,17 +1,18 @@
 #!./perl -T
 
+use Config;
 BEGIN {
     chdir 't' if -d 't';
     @INC = '../lib';
-    require Config;
-    if (($Config::Config{'extensions'} !~ m!\bList/Util\b!) ){
+    if (($Config{'extensions'} !~ m!\bList/Util\b!) ){
 	print "1..0 # Skip -- Perl configured without List::Util module\n";
 	exit 0;
     }
 }
 
-my $no_taint_support = exists($Config::Config{taint_support})
-                     && !$Config::Config{taint_support};
+my $NoTaintSupport =
+    (exists($Config{taint_support}) && !$Config{taint_support}) ||
+    $Config{ccflags} =~ /-DSILENT_NO_TAINT_SUPPORT/;
 
 my %skip_fetch_count_when_no_taint = (
     '<${$ts}> RT57012_OV' => 1,
@@ -24,7 +25,7 @@ my %skip_fetch_count_when_no_taint = (
 
 sub is_if_taint_supported {
     my ($got, $expected, $name, @mess) = @_;
-    if ($expected && $no_taint_support) {
+    if ($expected && $NoTaintSupport) {
         return skip("your perl was built without taint support");
     }
     else {
@@ -2052,7 +2053,7 @@ foreach my $op (qw(<=> == != < <= > >=)) {
 		    my $exp_fetch = ($var eq '$ts') ?
 			    $exp_fetch_s : $exp_fetch_a;
 		    SKIP: {
-			if ($skip_fetch_count_when_no_taint{$desc} && $no_taint_support) {
+			if ($skip_fetch_count_when_no_taint{$desc} && $NoTaintSupport) {
 			    skip("your perl was built without taint support");
 			}
 			else {
diff --git a/lib/perl5db.t b/lib/perl5db.t
index c38e9994bc3a..5acff938b7cd 100644
--- a/lib/perl5db.t
+++ b/lib/perl5db.t
@@ -687,8 +687,10 @@ sub _calc_trace_wrapper
 }
 
 # taint tests
-if (!exists($Config{taint_support}) || $Config{taint_support})
-{
+if (
+    (!exists($Config{taint_support}) || $Config{taint_support}) &&
+    $Config{ccflags} !~ /-DSILENT_NO_TAINT_SUPPORT/
+) {
     my $wrapper = _calc_trace_wrapper(
         {
             prog => '../lib/perl5db/t/taint',
diff --git a/t/lib/warnings/taint b/t/lib/warnings/taint
index 12bcc2597551..860869090720 100644
--- a/t/lib/warnings/taint
+++ b/t/lib/warnings/taint
@@ -10,7 +10,7 @@ def
 # taint.c
 use Config;
 BEGIN {
-    if ( exists($Config{taint_support}) && not $Config{taint_support}) {
+    if ( (exists($Config{taint_support}) && not $Config{taint_support}) || $Config{ccflags} =~ /-DSILENT_NO_TAINT_SUPPORT/) {
 	print "SKIPPED\n# your perl was built without taint support\n";
 	exit 0;
     }
@@ -30,7 +30,7 @@ def
 # taint.c
 use Config;
 BEGIN {
-    if ( exists($Config{taint_support}) && not $Config{taint_support}) {
+    if ( (exists($Config{taint_support}) && not $Config{taint_support}) || $Config{ccflags} =~ /-DSILENT_NO_TAINT_SUPPORT/) {
 	print "SKIPPED\n# your perl was built without taint support\n";
 	exit 0;
     }
@@ -58,7 +58,7 @@ def
 # taint.c
 use Config;
 BEGIN {
-    if ( exists($Config{taint_support}) && not $Config{taint_support}) {
+    if ( (exists($Config{taint_support}) && not $Config{taint_support}) || $Config{ccflags} =~ /-DSILENT_NO_TAINT_SUPPORT/) {
 	print "SKIPPED\n# your perl was built without taint support\n";
 	exit 0;
     }
diff --git a/t/op/taint.t b/t/op/taint.t
index daeb164efafe..b2c308b3d7c6 100644
--- a/t/op/taint.t
+++ b/t/op/taint.t
@@ -18,7 +18,9 @@ use strict;
 use warnings;
 use Config;
 
-my $NoTaintSupport = exists($Config{taint_support}) && !$Config{taint_support};
+my $NoTaintSupport = 
+    (exists($Config{taint_support}) && !$Config{taint_support}) ||
+    $Config{ccflags} =~ /-DSILENT_NO_TAINT_SUPPORT/;
 
 if ($NoTaintSupport) {
     skip_all("your perl was built without taint support");
diff --git a/t/perf/taint.t b/t/perf/taint.t
index 22a35608e2e4..7206184fefa3 100644
--- a/t/perf/taint.t
+++ b/t/perf/taint.t
@@ -20,7 +20,10 @@ BEGIN {
     require Config; import Config;
     require './test.pl';
     skip_all_if_miniperl("No Scalar::Util under miniperl");
-    if (exists($Config{taint_support}) && !$Config{taint_support}) {
+    if (
+        (exists($Config{taint_support}) && !$Config{taint_support}) ||
+        $Config{ccflags} =~ /-DSILENT_NO_TAINT_SUPPORT/
+    ) {
         skip_all("built without taint support");
     }
 }
diff --git a/t/run/runenv.t b/t/run/runenv.t
index b32b4f20a9e7..40d972a220bb 100644
--- a/t/run/runenv.t
+++ b/t/run/runenv.t
@@ -124,7 +124,10 @@ try({PERL5OPT => '-w -w'},
     '');
 
 SKIP: {
-    if (exists($Config{taint_support}) && !$Config{taint_support}) {
+    if (
+        (exists($Config{taint_support}) && !$Config{taint_support}) ||
+        $Config{ccflags} =~ /-DSILENT_NO_TAINT_SUPPORT/
+    ) {
         skip("built without taint support", 2);
     }
     try({PERL5OPT => '-t'},
diff --git a/t/run/switcht.t b/t/run/switcht.t
index 533d8be992fd..8b12bc33df5e 100644
--- a/t/run/switcht.t
+++ b/t/run/switcht.t
@@ -8,7 +8,10 @@ BEGIN {
 
 use Config;
 
-if (exists($Config{taint_support}) && !$Config{taint_support}) {
+if (
+    (exists($Config{taint_support}) && !$Config{taint_support}) ||
+    $Config{ccflags} =~ /-DSILENT_NO_TAINT_SUPPORT/
+) {
     skip_all("perl built without taint support");
 }