diff --git a/CHANGELOG.md b/CHANGELOG.md
index 93a2858ed5d4..198300bf2c07 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -12,6 +12,7 @@ These changes are available in the [master branch](https://github.com/PrefectHQ/
 
 - Add a `save`/`load` interface to Flows - [#1685](https://github.com/PrefectHQ/prefect/pull/1685)
 - Add option to specify `aws_session_token` for the `FargateTaskEnvironment` - [#1688](https://github.com/PrefectHQ/prefect/pull/1688)
+- Add an informative version header to all Cloud client requests - [#1690](https://github.com/PrefectHQ/prefect/pull/1690)
 
 ### Task Library
 
diff --git a/src/prefect/client/client.py b/src/prefect/client/client.py
index 6b592c21d1cc..4a02ea09c419 100644
--- a/src/prefect/client/client.py
+++ b/src/prefect/client/client.py
@@ -265,6 +265,7 @@ def _request(
         headers = headers or {}
         if token:
             headers["Authorization"] = "Bearer {}".format(token)
+        headers["X-PREFECT-CORE-VERSION"] = str(prefect.__version__)
 
         session = requests.Session()
         retries = Retry(
diff --git a/tests/client/test_client.py b/tests/client/test_client.py
index 73b5baad5689..9ec88974ad12 100644
--- a/tests/client/test_client.py
+++ b/tests/client/test_client.py
@@ -31,6 +31,36 @@ def test_client_posts_to_api_server(patch_post):
     assert post.call_args[0][0] == "http://my-cloud.foo/foo/bar"
 
 
+def test_version_header(monkeypatch):
+    get = MagicMock()
+    session = MagicMock()
+    session.return_value.get = get
+    monkeypatch.setattr("requests.Session", session)
+    with set_temporary_config(
+        {"cloud.graphql": "http://my-cloud.foo", "cloud.auth_token": "secret_token"}
+    ):
+        client = Client()
+    client.get("/foo/bar")
+    assert get.call_args[1]["headers"]["X-PREFECT-CORE-VERSION"] == str(
+        prefect.__version__
+    )
+
+
+def test_version_header_cant_be_overridden(monkeypatch):
+    get = MagicMock()
+    session = MagicMock()
+    session.return_value.get = get
+    monkeypatch.setattr("requests.Session", session)
+    with set_temporary_config(
+        {"cloud.graphql": "http://my-cloud.foo", "cloud.auth_token": "secret_token"}
+    ):
+        client = Client()
+    client.get("/foo/bar", headers={"X-PREFECT-CORE-VERSION": "-1",})
+    assert get.call_args[1]["headers"]["X-PREFECT-CORE-VERSION"] == str(
+        prefect.__version__
+    )
+
+
 def test_client_posts_graphql_to_api_server(patch_post):
     post = patch_post(dict(data=dict(success=True)))
 
diff --git a/tests/client/test_client_auth.py b/tests/client/test_client_auth.py
index 0bb288b32170..c77f11460cc2 100644
--- a/tests/client/test_client_auth.py
+++ b/tests/client/test_client_auth.py
@@ -180,7 +180,10 @@ def test_login_uses_api_token(self, patch_post):
         )
         client = Client(api_token="api")
         client.login_to_tenant(tenant_id=tenant_id)
-        assert post.call_args[1]["headers"] == dict(Authorization="Bearer api")
+        assert post.call_args[1]["headers"] == {
+            "Authorization": "Bearer api",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
+        }
 
     def test_login_uses_api_token_when_access_token_is_set(self, patch_post):
         tenant_id = str(uuid.uuid4())
@@ -200,7 +203,10 @@ def test_login_uses_api_token_when_access_token_is_set(self, patch_post):
         client._access_token = "access"
         client.login_to_tenant(tenant_id=tenant_id)
         assert client.get_auth_token() == "ACCESS_TOKEN"
-        assert post.call_args[1]["headers"] == dict(Authorization="Bearer api")
+        assert post.call_args[1]["headers"] == {
+            "Authorization": "Bearer api",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
+        }
 
     def test_graphql_uses_access_token_after_login(self, patch_post):
         tenant_id = str(uuid.uuid4())
@@ -219,12 +225,18 @@ def test_graphql_uses_access_token_after_login(self, patch_post):
         client = Client(api_token="api")
         client.graphql({})
         assert client.get_auth_token() == "api"
-        assert post.call_args[1]["headers"] == dict(Authorization="Bearer api")
+        assert post.call_args[1]["headers"] == {
+            "Authorization": "Bearer api",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
+        }
 
         client.login_to_tenant(tenant_id=tenant_id)
         client.graphql({})
         assert client.get_auth_token() == "ACCESS_TOKEN"
-        assert post.call_args[1]["headers"] == dict(Authorization="Bearer ACCESS_TOKEN")
+        assert post.call_args[1]["headers"] == {
+            "Authorization": "Bearer ACCESS_TOKEN",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
+        }
 
     def test_login_to_tenant_writes_tenant_and_reloads_it_when_token_is_reloaded(
         self, patch_post
@@ -364,7 +376,10 @@ def test_refresh_token_passes_refresh_token_as_header(self, patch_post):
         client = Client()
         client._refresh_token = "refresh"
         client._refresh_access_token()
-        assert post.call_args[1]["headers"] == dict(Authorization="Bearer refresh")
+        assert post.call_args[1]["headers"] == {
+            "Authorization": "Bearer refresh",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
+        }
 
     def test_get_available_tenants(self, patch_post):
         tenants = [
@@ -466,6 +481,7 @@ def test_headers_are_passed_to_get(self, monkeypatch):
         assert get.call_args[1]["headers"] == {
             "x": "y",
             "Authorization": "Bearer secret_token",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
         }
 
     def test_headers_are_passed_to_post(self, monkeypatch):
@@ -482,6 +498,7 @@ def test_headers_are_passed_to_post(self, monkeypatch):
         assert post.call_args[1]["headers"] == {
             "x": "y",
             "Authorization": "Bearer secret_token",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
         }
 
     def test_headers_are_passed_to_graphql(self, monkeypatch):
@@ -498,6 +515,7 @@ def test_headers_are_passed_to_graphql(self, monkeypatch):
         assert post.call_args[1]["headers"] == {
             "x": "y",
             "Authorization": "Bearer secret_token",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
         }
 
     def test_tokens_are_passed_to_get(self, monkeypatch):
@@ -509,7 +527,10 @@ def test_tokens_are_passed_to_get(self, monkeypatch):
             client = Client()
         client.get("/foo/bar", token="secret_token")
         assert get.called
-        assert get.call_args[1]["headers"] == {"Authorization": "Bearer secret_token"}
+        assert get.call_args[1]["headers"] == {
+            "Authorization": "Bearer secret_token",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
+        }
 
     def test_tokens_are_passed_to_post(self, monkeypatch):
         post = MagicMock()
@@ -520,7 +541,10 @@ def test_tokens_are_passed_to_post(self, monkeypatch):
             client = Client()
         client.post("/foo/bar", token="secret_token")
         assert post.called
-        assert post.call_args[1]["headers"] == {"Authorization": "Bearer secret_token"}
+        assert post.call_args[1]["headers"] == {
+            "Authorization": "Bearer secret_token",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
+        }
 
     def test_tokens_are_passed_to_graphql(self, monkeypatch):
         post = MagicMock()
@@ -531,4 +555,7 @@ def test_tokens_are_passed_to_graphql(self, monkeypatch):
             client = Client()
         client.graphql("query {}", token="secret_token")
         assert post.called
-        assert post.call_args[1]["headers"] == {"Authorization": "Bearer secret_token"}
+        assert post.call_args[1]["headers"] == {
+            "Authorization": "Bearer secret_token",
+            "X-PREFECT-CORE-VERSION": str(prefect.__version__),
+        }